Prevalence and related factors of suicide attempts in first-episode and untreated Chinese Han outpatients with psychotic major depression

2020 ◽  
Vol 270 ◽  
pp. 108-113
Author(s):  
Hehua Li ◽  
Yuanyuan Huang ◽  
Fengchun Wu ◽  
XiaoE Lang ◽  
Xiang Yang Zhang
Keyword(s):  
Major Depression ◽  
Suicide Attempts ◽  
First Episode ◽  
Chinese Han ◽  
Related Factors ◽  
Psychotic Major Depression

scholarly journals The prevalence and related factors of metabolic syndrome in outpatients with first-episode drug-naive major depression comorbid with anxiety

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yinghua Zhong ◽  
Manji Hu ◽  
Qiang Wang ◽  
Zhendong Yang ◽  
Na Zhu ◽  
...  
Keyword(s):  
Attempted Suicide ◽  
Rating Scale ◽  
Suicide Attempts ◽  
Psychiatric Symptoms ◽  
First Episode ◽  
Chinese Han ◽  
Related Factors ◽  
History Of ◽  
Drug Naïve ◽  
Tsh Levels

AbstractMetabolic syndrome (MetS) is associated with depression, but its role in major depressive disorder comorbid with anxiety (AMD) is unclear. This study aimed to investigate the prevalence and clinical correlates of MetS in first-episode drug-naive (FEDN) patients with AMD in a Chinese Han population. In total, 1380 FEDN outpatients with AMD were recruited in this cross-sectional study. The sociodemographic features, clinical characteristics, history of suicide attempts, thyroid-stimulating hormone (TSH) levels, and MetS parameters of each subject were evaluated. All subjects were rated on the Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), and the Positive and Negative Syndrome Scale positive symptom subscale. The prevalence of MetS among AMD patients was 8.04%. Compared to the non-MetS group, age, age of onset, TSH level, HAM-A and HAM-D scores, history of attempted suicide, and comorbid psychiatric symptoms were higher in the MetS group. Those in this group were also more likely to be married, and they had a lower educational level. Furthermore, age, psychiatric symptoms, suicide attempts, and higher TSH levels were independently associated with MetS in AMD patients. This study suggests a lower prevalence of MetS in FEDN patients with AMD in a Chinese Han population. Older age, comorbid psychiatric symptoms, history of attempted suicide, and higher TSH levels are related factors for MetS in AMD patients.

scholarly journals Ten-year outcomes in first episode psychotic major depression patients compared with schizophrenia and bipolar patients

2016 ◽  
Vol 176 (2-3) ◽  
pp. 417-422 ◽  
Author(s):  
M. Heslin ◽  
J.M. Lappin ◽  
K. Donoghue ◽  
B. Lomas ◽  
U. Reininghaus ◽  
...  
Keyword(s):  
Major Depression ◽  
First Episode ◽  
Psychotic Major Depression ◽  
Bipolar Patients

scholarly journals Predictors of first lifetime episodes of major depression in midlife women

2008 ◽  
Vol 39 (1) ◽  
pp. 55-64 ◽  
Author(s):  
J. T. Bromberger ◽  
H. M. Kravitz ◽  
K. Matthews ◽  
A. Youk ◽  
C. Brown ◽  
...  
Keyword(s):  
Major Depression ◽  
Life Stress ◽  
White Women ◽  
Stressful Life Event ◽  
Reproductive Hormones ◽  
First Episode ◽  
Related Factors ◽  
Health Related ◽  
History Of ◽  
Axis I

BackgroundLittle is known about factors that predict first lifetime episodes of major depression in middle-aged women. It is not known whether health-related factors and life stress pose more or less of a risk to the onset of clinical depression than does the menopausal transition.MethodThe Structured Clinical Interview for DSM-IV Axis I Disorders (SCID) was used to assess diagnoses of lifetime, annual and current major depression in a community-based sample of premenopausal or early perimenopausal African American and White women. Menstrual cycle characteristics, psychosocial and health-related factors, and blood samples for assay of reproductive hormones were obtained annually. Two hundred and sixty-six women without a history of major depression at baseline constituted the cohort for the current analyses.ResultsOver 7 years of follow-up, 42 (15.8%) women met criteria for a diagnosis of major depression. Frequent vasomotor symptoms (VMS; hot flashes and/or night sweats) (HR 2.14, p=0.03) were a significant predictor of major depression in univariate analyses. After simultaneous adjustment for multiple predictors in Cox proportional hazards analyses, frequent VMS were no longer significant; lifetime history of an anxiety disorder (HR 2.20, p=0.02) and role limitations due to physical health (HR 1.88, p=0.07) at baseline and a very stressful life event (HR 2.25, p=0.04) prior to depression onset predicted a first episode of major depression.ConclusionsBoth earlier (e.g. history of anxiety disorders) and more proximal factors (e.g. life stress) may be more important than VMS in contributing to a first episode of major depression during midlife.

Kognitiontest können früh auf Depression hinweisen

2018 ◽  
Vol 86 (08) ◽  
pp. 460-461
Keyword(s):  
Major Depression ◽  
First Episode

Bei einer Major Depression lassen sich in vielen kognitiven Domänen Dysfunktionen nachweisen. Ob solche Defizite auch bei einer ersten Episode einer unipolaren Depression (first episode depression, FED) nachweisbar sind und wie sie sich im weiteren Verlauf entwickeln, prüften Muriel Vicent-Gil von der psychiatrischen Abteilung des Hospitals de la Santa Creu i Sant Pau in Barcelona und ihre Kollegen aus ganz Spanien.

scholarly journals Clinical characteristics and sociodemographic features of psychotic major depression

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Meng-qi Wang ◽  
Ran-ran Wang ◽  
Yu Hao ◽  
Wei-feng Xiong ◽  
Ling Han ◽  
...  
Keyword(s):  
Family History ◽  
Major Depression ◽  
Clinical Characteristics ◽  
Missing Values ◽  
Psychotic Disorders ◽  
Mental Health Center ◽  
Psychiatric Diseases ◽  
First Onset ◽  
History Of ◽  
Psychotic Major Depression

Abstract Background Psychotic major depression (PMD) is a subtype of depression with a poor prognosis. Previous studies have failed to find many differences between patients with PMD and those with non-psychotic major depression (NMD) or schizophrenia (SZ). We compared sociodemographic factors (including season of conception) and clinical characteristics between patients with PMD, NMD, and schizophrenia. Our aim was to provide data to help inform clinical diagnoses and future etiology research. Methods This study used data of all patients admitted to Shandong Mental Health Center from June 1, 2016 to December 31, 2017. We analyzed cases who had experienced an episode of PMD (International Classification of Diseases, Tenth Revision codes F32.3, F33.3), NMD (F32.0–2/9, F33.0–2/9), and SZ (F20–20.9). Data on sex, main discharge diagnosis, date of birth, ethnicity, family history of psychiatric diseases, marital status, age at first onset, education, allergy history, and presence of trigger events were collected. Odds ratios (OR) were calculated using logistic regression analyses. Missing values were filled using the k-nearest neighbor method. Results PMD patients were more likely to have a family history of psychiatric diseases in their first-, second-, and third-degree relatives ([OR] 1.701, 95% confidence interval [CI] 1.019–2.804) and to have obtained a higher level of education (OR 1.451, 95% CI 1.168–1.808) compared with depression patients without psychotic features. Compared to PMD patients, schizophrenia patients had lower education (OR 0.604, 95% CI 0.492–0.741), were more often divorced (OR 3.087, 95% CI 1.168–10.096), had a younger age of onset (OR 0.934, 95% CI 0.914–0.954), less likely to have a history of allergies (OR 0.604, 95% CI 0.492–0.741), and less likely to have experienced a trigger event 1 year before first onset (OR 0.420, 95% CI 0.267–0.661). Season of conception, ethnicity, and sex did not differ significantly between PMD and NMD or schizophrenia and PMD. Conclusions PMD patients have more similarities with NMD patients than SZ patients in terms of demographic and clinical characteristics. The differences found between PMD and SZ, and PMD and NMD correlated with specificity of the diseases. Furthermore, allergy history should be considered in future epidemiological studies of psychotic disorders.

scholarly journals Antidepressant and antipsychotic treatment of Psychotic Major Depression in a British mental healthcare setting

2021 ◽  
pp. 1-7
Author(s):  
Eshim S. Jami ◽  
Megan Pritchard ◽  
Hitesh Shetty ◽  
Robert Stewart ◽  
Allan H. Young ◽  
...  
Keyword(s):  
Major Depression ◽  
Mental Healthcare ◽  
Healthcare Setting ◽  
Antipsychotic Treatment ◽  
Psychotic Major Depression

Nightmares, suicide attempts, and melancholic features in patients with unipolar major depression

2007 ◽  
Vol 98 (3) ◽  
pp. 267-270 ◽  
Author(s):  
Mehmet Yucel Agargun ◽  
Lutfullah Besiroglu ◽  
Ali Savas Cilli ◽  
Mustafa Gulec ◽  
Adem Aydin ◽  
...  
Keyword(s):  
Major Depression ◽  
Suicide Attempts ◽  
Unipolar Major Depression

scholarly journals Neuropsychological deficits in past suicide attempters with varying levels of depression severity

2014 ◽  
Vol 44 (14) ◽  
pp. 2965-2974 ◽  
Author(s):  
J. G. Keilp ◽  
S. R. Beers ◽  
A. K. Burke ◽  
N. M. Melhem ◽  
M. A. Oquendo ◽  
...  
Keyword(s):  
Working Memory ◽  
Major Depression ◽  
Rating Scale ◽  
Suicide Attempts ◽  
Past History ◽  
Clinical State ◽  
Suicide Attempters ◽  
History Of ◽  
Attention Memory ◽  
Interference Processing

BackgroundOur previous work identified deficits in interference processing and learning/memory in past suicide attempters who were currently depressed and medication-free. In this study, we extend this work to an independent sample studied at various stages of illness and treatment (mild symptoms, on average) to determine if these deficits in past suicide attempters are evident during a less severe clinical state.MethodA total of 80 individuals with a past history of major depression and suicide attempt were compared with 81 individuals with a history of major depression and no lifetime suicide attempts on a battery of neurocognitive measures assessing attention, memory, abstract/contingent learning, working memory, language fluency and impulse control.ResultsPast attempters performed more poorly in attention, memory and working memory domains, but also in an estimate of pre-morbid intelligence. After correction for this estimate, tests that had previously distinguished past attempters – a computerized Stroop task and the Buschke Selective Reminding Test – remained significantly worse in attempters. In a secondary analysis, similar differences were found among those with the lowest levels of depression (Hamilton Depression Rating Scale score <10), suggesting that these deficits may be trait markers independent of current symptomatology.ConclusionsDeficits in interference processing and learning/memory constitute an enduring defect in information processing that may contribute to poor adaptation, other higher-order cognitive impairments and risk for suicidal behavior.

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