scholarly journals Comorbid Depression and Treatment of Anxiety Disorders, OCD, and PTSD: Diagnosis versus Severity

Author(s):  
J. Klein Breteler ◽  
N. Ikani ◽  
E.S. Becker ◽  
J. Spijker ◽  
G. Hendriks
PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0166116 ◽  
Author(s):  
Lonneke A. van Tuijl ◽  
Klaske A. Glashouwer ◽  
Claudi L. H. Bockting ◽  
Jorge N. Tendeiro ◽  
Brenda W. J. H. Penninx ◽  
...  

2015 ◽  
Vol 23 (10) ◽  
pp. 1178-1187 ◽  
Author(s):  
Brian T. Wymbs ◽  
Anne E. Dawson

Objective: Researchers are increasingly using Amazon’s Mechanical Turk (MTurk; www.mturk.com ) to recruit study participants. However, the utility of MTurk for investigations of ADHD in adulthood is unknown. Method: A total of 6,526 MTurk workers (median age range = 26-35 years) completed an online screening survey assessing their diagnostic histories and symptoms of ADHD, as well as relevant demographic correlates and diagnostic comorbidity. Results: The prevalence of MTurk workers who reported being diagnosed as children and as adults, and the percentage of workers whose ADHD appeared to persist from childhood into adulthood, are consistent with those observed in “offline” samples. Relative to MTurk workers diagnosed with ADHD as adults, workers diagnosed with ADHD as children were more likely to be male and without college degrees, as well as less likely to have comorbid depression or anxiety disorders. Conclusion: Amazon’s MTurk holds promise as a recruitment tool for studying adults with ADHD.


Author(s):  
Mark A. Whisman ◽  
Daniel BE

Depression often co-occurs with other Axis I and Axis II psychiatric disorders. This chapter presents a model for how cognitive therapy (CT) of depression can be adapted in conceptualizing and treating the complex set of issues and problems that often accompany comorbid depression. It begins with a discussion of the prevalence of comorbidity in community and clinical samples, then review the research on comorbidity and outcome to CT for depression, followed by a model for adapting or modifying CT for patients who present with depression and a comorbid Axis I or Axis II disorder. The chapter concludes with specific clinical guidelines for treating depression that co-occurs with anxiety disorders, substance use disorders, and personality disorders.


2020 ◽  
Vol 63 (1) ◽  
Author(s):  
Maud De Venter ◽  
Bernet M. Elzinga ◽  
Filip Van Den Eede ◽  
Kristien Wouters ◽  
Guido F. Van Hal ◽  
...  

Abstract Background: To examine the association between childhood trauma and work functioning, and to elucidate to what extent this association can be accounted for by depression and/or anxiety. Methods: Data of 1,649 working participants were derived from the Netherlands Study of Depression and Anxiety (NESDA, n = 2,981). Childhood trauma (emotional neglect, psychological, physical, and sexual abuse before age 16) was assessed with a structured interview and work functioning, in terms of absenteeism and presenteeism, with the Health and Labor Questionnaire Short Form (SF-HLQ) and the World Health Organization Disability Assessment Schedule II (WHODAS-II), respectively. Depressive and/or anxiety disorders were assessed with the Composite Interview Diagnostic Instrument (CIDI). Mediation analyses were conducted. Results: At baseline, 44.8% reported to have experienced childhood trauma. Workers with the highest childhood trauma level showed significantly (p < 0.001) more absenteeism as well as more presenteeism. Mediation analyses revealed that indirect effects between the childhood trauma index and both work indices were significantly mediated by current depressive disorder (p = 0.023 and p < 0.001, respectively) and current comorbid depression-anxiety (p = 0.020 and p < 0.001, respectively), with the latter accounting for the largest effects (PM = 0.23 and PM = 0.29, respectively). No significant mediating role in this relationship was found for current anxiety disorder and remitted depressive and/or anxiety disorder. Conclusions: Persons with childhood trauma have significantly reduced work functioning in terms of absenteeism and presenteeism. This seems to be largely accounted for by current depressive disorders and current comorbid depression-anxiety.


Author(s):  
Louise F. Kimura ◽  
Leonardo S. Novaes ◽  
Gisele Picolo ◽  
Carolina D. Munhoz ◽  
Chi W. Cheung ◽  
...  

1995 ◽  
Vol 166 (3) ◽  
pp. 328-332 ◽  
Author(s):  
P. W. Burvill ◽  
G. A. Johnson ◽  
K. D. Jamrozik ◽  
C. S. Anderson ◽  
E. G. Stewart-Wynne ◽  
...  

BackgroundThe prevalence of anxiety disorders in 294 patients who survived to four months in the Perth Community Stroke Study (Perth, Australia), and a follow-up of these patients at 12 months, are presented.MethodDiagnoses are described both in the usual DSM hierarchic format and by a non-hierarchic approach. Adoption of the hierarchic approach alone greatly underestimates the prevalence of anxiety disorders.ResultsMost cases were of agoraphobia, and the remainder were generalised anxiety disorder. The prevalence of anxiety disorders alone was 5% in men and 19% in women; in community controls, it was 5% in men and 8% in women. Adopting a non-hierarchic approach to diagnosis gave a prevalence of 12% in men and 28% in women. When those who showed evidence of anxiety disorder before stroke were subtracted, the latter prevalence was 9% in men and 20% in women.ConclusionOne-third of the men and half of the women with post-stroke anxiety disorders showed evidence of either depression or an anxiety disorder at the time of the stroke. At 12 month follow-up of 49 patients with agoraphobia by a non-hierarchic approach, 51 % had recovered, and equal proportions of the remainder had died or still had agoraphobia. The only major difference in outcome between those with anxiety disorder alone and those with comorbid depression was the greater mortality in the latter.


2021 ◽  
pp. 1-11
Author(s):  
Sasha D'Arcy ◽  
Peter J. Norton

Abstract During psychotherapy some patients experience large symptom improvements between sessions, termed sudden gains. Most commonly, sudden gains are observed during treatment for depression (40–50% of participants), but these are occasionally also observed in treatment for anxiety (15–20%). This study investigated the impact of comorbid depression on sudden gains in a primary anxiety sample. It was hypothesised that sudden gains would occur more frequently in participants with anxiety and comorbid depression than anxiety-only participants. The sample consisted of 58 adults who participated in a 12-week transdiagnostic cognitive-behavioural therapy (tCBT) programme. Sudden gains were more frequent in the comorbid depression group than in the anxiety-only group. Sudden gains may be predominantly a function of depressive disorders, which supports the higher rates seen in depressive disorders compared with anxiety disorders. Future research should endeavour to replicate these findings, as this was the first study designed to specifically investigate comorbidity in sudden gains.


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