Minor Impact of Multiple Psychiatric Symptoms on Quality of Life (EQ5D) in Psychogeriatric Patients: A Clinical-Empirical Structural Modeling Approach

Parkinson’s disease (PD) is a complex disorder characterized by a wide spectrum of symptoms. Depression and anxiety are common manifestations in PD and may be determinants of health-related quality of life (HRQoL). The objective of this study is to determine the association of depression and anxiety with the dimensions of HRQoL in subjects with PD enrolled in an association of patients. Ninety-five community-based patients with PD diagnosis at different disease stages were studied. HRQoL was assessed using the Parkinson’s Disease Questionnaire (PDQ-39); depression and anxiety were assessed using the Beck Depression Inventory (BDI-II) and the State-Trait Anxiety Inventory (STAI), respectively. Our results showed that depression and anxiety were negatively associated with HRQoL measured by PDSI. Higher motor dysfunction measured by Hoehn and Yahr (H&Y) staging was also associated with worse HRQoL. Depression was the most influential variable in the model. All PDQ-39 dimensions except social support and bodily discomfort were associated with depression. Anxiety was associated with the emotional well-being and bodily discomfort dimensions. These results suggest that physicians should pay attention to the presence of psychiatric symptoms and treat them appropriately.

Download Full-text

Management of Traumatic Ulcerations of Lips in a Case of Huntington’s Disease: A Novel Application of Essix Retainer

The Journal of Indian Orthodontic Society ◽

10.1177/03015742211023469 ◽

2021 ◽

pp. 030157422110234

Author(s):

Mohamed Iqbal J

Keyword(s):

Quality Of Life ◽

Characteristic Feature ◽

Neurodegenerative Disease ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Complete Resolution ◽

Psychiatric Symptoms

Huntington’s disease is a progressive neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms. Dystonia of muscles is a characteristic feature of this condition. A case of Huntington’s disease, with orofacial dystonia, leading to severe uncontrolled biting of the lips, was referred by the Department of Neurology. Deep traumatic ulcerations were found in both upper and lower lips. A simple Essix retainer was fabricated and inserted, which acted as a barrier for the teeth from injuring the lips. The ulcers showed complete resolution in 3 to 4 weeks. The vacuum-formed retainers resulted in a good fit and resisted removal by the uncontrolled contortions of the orofacial muscles. The Essix retainer can be effectively used in improving the quality of life of patients, with Huntington’s disease, having such dystonia-related injuries to lips.

Download Full-text

Affective Temperaments and Illness Severity in Patients with Bipolar Disorder

Medicina ◽

10.3390/medicina57010054 ◽

2021 ◽

Vol 57 (1) ◽

pp. 54

Author(s):

Mario Luciano ◽

Luca Steardo ◽

Gaia Sampogna ◽

Vito Caivano ◽

Carmen Ciampi ◽

...

Keyword(s):

Quality Of Life ◽

Bipolar Disorder ◽

Protective Factor ◽

Psychiatric Symptoms ◽

Control Group ◽

Term Outcome ◽

Long Term Outcome ◽

Affective Temperaments

Background and objectives: Bipolar disorder (BD) is one of the most burdensome psychiatric illnesses, being associated with a negative long-term outcome and the highest suicide rate. Although affective temperaments can impact on BD long-term outcome, their role remains poorly investigated. The aims of the present study are to describe the clinical characteristics of patients with BD more frequently associated with the different affective temperaments and to assess the relation between affective temperaments and severity of clinical picture in a sample of patients with BD. Materials and Methods: A total of 199 patients have been recruited in the outpatients units of two university sites. Patients’ psychiatric symptoms, affective temperaments, and quality of life were investigated through validated assessment instruments. Results: Predominant cyclothymic and irritable temperaments are associated to higher number of relapses, poorer quality of life, higher rates of aggressive behaviors, and suicide attempts. Conversely, the predominant hyperthymic disposition was a protective factor for several outcome measures, including relapse rate, severity of anxiety, depressive and manic symptoms, suicidality, and earlier age at onset. One limitationo of the present study is that the recruitment took place in two university sites; therefore, our findings cannot be fully generalized to the whole community of BD patients. Other limitations are the lack of a control group and the cross-sectional design of the study. Conclusions: The early identification of affective temperaments can help clinicians to identify those BD patients who are more likely to show a poor long-term outcome. An early screening of affective temperaments can be useful to develop targeted integrated pharmacological and psychosocial interventions.

Download Full-text

Quality of life, social support, and severity of psychiatric symptoms in Jordanian patients with schizophrenia

Journal of Psychiatric and Mental Health Nursing ◽

10.1111/jpm.12112 ◽

2013 ◽

Vol 21 (5) ◽

pp. 455-465 ◽

Cited By ~ 13

Author(s):

S. Hamaideh ◽

D. Al-Magaireh ◽

B. Abu-Farsakh ◽

H. Al-Omari

Keyword(s):

Quality Of Life ◽

Social Support ◽

Psychiatric Symptoms

Download Full-text

‘Teaching Me to Parent Myself’: The Feasibility of an In-Patient Group Schema Therapy Programme for Complex Trauma

Behavioural and Cognitive Psychotherapy ◽

10.1017/s1352465817000698 ◽

2017 ◽

Vol 46 (4) ◽

pp. 463-478

Author(s):

Rita Younan ◽

Joan Farrell ◽

Tamara May

Keyword(s):

Quality Of Life ◽

Complex Trauma ◽

Psychiatric Symptoms ◽

Self Esteem ◽

Post Treatment ◽

Drop Out ◽

Schema Therapy ◽

Schema Modes ◽

Therapy Programme

Background: Group schema therapy is an emerging treatment for personality and other psychiatric disorders. It may be particularly suited to individuals with complex trauma given that early abuse is likely to create maladaptive schemas. Aims: This pilot study explored the feasibility and effectiveness of a 4-week in-patient group schema therapy programme for adults with complex trauma in a psychiatric hospital setting. Method: Thirty-six participants with complex trauma syndrome participated in this open trial. Treatment consisted of 60 hours of group schema therapy and 4 hours of individual schema therapy administered over 4 weeks. Feasibility measures included drop-out rates, qualitative interviews with participants to determine programme acceptability and measures of psychiatric symptoms, self-esteem, quality of life and schema modes pre-, post- and 3 months following the intervention. Results: Drop-out rate for the 4-week program was 11%. Thematic analysis of interview transcripts revealed four major themes: connection, mode language explained emotional states, identifying the origin of the problem and the emotional activation of the programme. Measures of psychiatric symptoms, self-esteem and quality of life showed improvement post-treatment and at 3 months post-treatment. There was a reduction in most maladaptive schema modes pre-/post-treatment. Conclusions: A group schema therapy approach for complex trauma is feasible and demonstrates positive effects on psychiatric symptoms and maladaptive schemas.

Download Full-text

Therapeutic management of movement disorders present in Huntington’s Disease: a literature review

10.5327/1516-3180.430 ◽

2021 ◽

Author(s):

Camila Angelo Vidal de Figueiredo ◽

Kaline dos Santos Kishishita Castro ◽

Sílvia Raimunda Costa Leite

Keyword(s):

Quality Of Life ◽

Literature Review ◽

Adverse Effects ◽

Huntington's Disease ◽

Huntington’S Disease ◽

Psychiatric Symptoms ◽

Therapeutic Management ◽

Abnormal Gait ◽

Botulinum Toxin Injections

Background: Huntington’s Disease (HD) is a hereditary neurodegenerative genetic disease with motor, cognitive and behavioral repercussions that interferes in several areas of the patients’ lives. Therefore, to increase the quality of life for patients the therapeutic management of symptoms is necessary. Objective: to elucidate the main forms of treatment that reduces motor disorders present in HD. Methods: an integrative literature review was conducted using scientific articles published between 2016-2020 about this topic found in Pubmed and Google Scholar databases. Results: the chorea treatment in HD can be done using Tetrabenazine, deutetrabenazine or antipsychotics. During a study by the Huntington Study Group (HSG), tetrabenazine proved its efficacy, however, due to several adverse effects, its use was reduced. Thus, deutetrabenazine was created, which consists in a tetrabenazine deuterated version, with a longer half- life and less adverse effects. Studies by the HSG found that besides reducing chorea, it also improves motor function in general in patients. Antipsychotics are used when the patient has behavioral and psychiatric symptoms that prevent him from using the other drugs. The dystonia treatment involves physiotherapy and botulinum toxin injections, which are also used in the bruxism therapy, along with mouth protectors. Abnormal gait and balance problems can be reduced with psychomotor rehabilitation, physiotherapy, and using a walker. Conclusion: the control of HD motor symptoms is an important way to increase patients’ quality of life. Therefore, more studies are necessary to expand the effective therapeutic options.

Download Full-text

Poor quality of life in Australian men: Cross-sectional associations with obesity, mobility, lifestyle and psychiatric symptoms

Maturitas ◽

10.1016/j.maturitas.2017.06.024 ◽

2017 ◽

Vol 103 ◽

pp. 32-36 ◽

Cited By ~ 2

Author(s):

Sharon L. Brennan-Olsen ◽

Julie A. Pasco ◽

Sarah M. Hosking ◽

Amelia G. Dobbins ◽

Lana J. Williams

Keyword(s):

Quality Of Life ◽

Psychiatric Symptoms ◽

Poor Quality ◽

Cross Sectional

Download Full-text

Quality of life measures and psychiatric symptoms in adolescents with systemic lupus erythematosus and familial Mediterranean fever

International Journal of Adolescent Medicine and Health ◽

10.1515/ijamh-2013-0332 ◽

2014 ◽

Vol 26 (4) ◽

pp. 541-549 ◽

Cited By ~ 4

Author(s):

Yasemin Düzçeker ◽

Nuray Ö. Kanbur ◽

Erkan Demirkaya ◽

Orhan Derman ◽

Lakshmi N. Moorthy ◽

...

Keyword(s):

Quality Of Life ◽

Systemic Lupus Erythematosus ◽

Familial Mediterranean Fever ◽

Lupus Erythematosus ◽

Psychiatric Symptoms ◽

Brief Symptom Inventory ◽

Systemic Lupus ◽

Global Quality Of Life ◽

Mediterranean Fever

Abstract Purpose: To describe the relation between global Quality of Life (QL) and psychiatric symptoms in adolescents with systemic lupus erythematosus (SLE) and familial Mediterranean fever (FMF), and to analyze the perceptions of parents and adolescents. Methods: This study included 51 adolescents diagnosed with SLE (n=25) and FMF (n=26), and 51 healthy adolescents. The Health Related QL (HRQL) of SLE patients was rated by parents and adolescents using the Simple Measurement of Impact of Lupus Erythematosus in Youngsters© (SMILEY©). The global QL of FMF patients and healthy adolescents was rated by the response given to the first question of the SMILEY© by each parent and adolescent. All participants completed the Brief Symptom Inventory (BSI), which measures psychiatric symptoms. Results: In total, 92.3% with FMF, 56% with SLE and 76.5% of healthy adolescents reported their global QL as good and very good using the first question of the SMILEY©. The global QL perceptions of adolescents and their parents did not correlate (FMF, p=0.94; SLE, p=0.16). SLE patients had the highest rate of depression (54.2%), whereas hostility was detected among 54.9% of healthy adolescents. Significant relations were detected between BSI and SMILEY© scores. Conclusion: The global QL perceptions of adolescents with FMF were better than those of healthy adolescents, which may be explained by their perceived relief of anguish they suffer during their short-lived attacks. The global QL perceptions of adolescents with SLE were the worst, most probably due to the chronic course resulting in an awareness of limitations and intense treatment. Adolescents with SLE had similar psychopathological symptom scores when compared with FMF patients and healthy adolescents. This could be explained by developing resilience. Differences in the perception of adolescents versus their parents regarding global QL emphasized the importance of adolescent-specific interviews for chronic illnesses and multidisciplinary follow-up with adolescent medicine.

Download Full-text

A Clinical Trial of Cognitive Behavior Therapy for Psychiatric Comorbidity and Quality of Life with Cancer Patients during Chemotherapy (CPdC)

10.21203/rs.3.rs-864827/v1 ◽

2021 ◽

Author(s):

Qasir Abbas ◽

Nimra Arooj ◽

Khawer Bilal Baig ◽

Muhammad Umer Khan ◽

Muhammad Khalid ◽

...

Keyword(s):

Quality Of Life ◽

Clinical Trial ◽

Psychological Distress ◽

Cancer Patients ◽

Death Anxiety ◽

Satisfaction With Life ◽

Psychiatric Symptoms ◽

Self Esteem ◽

Mean Difference

Abstract BackgroundCancer is a worldwide common illness, it evokes psychological distress at different stages, during chemotherapy patient perceives a variety of psychiatric symptoms due to various medication side-effects and psychological distress. Studies have shown a significant impact of CBT in the management of psychiatric symptoms during chemotherapy. This study aims to investigate the effectiveness of CBT for depression, anxiety, stress, death anxiety, satisfaction with life, and self-esteem among cancer patients during chemotherapy (CPdC).MethodsPlace and duration of the study: Department of Applied Psychology, Government College University Faisalabad in collaboration with Department of Oncology, Allied Hospital Faisalabad from November 20, 2020 and July 31, 2021. A total of 90 cancer patients were enrolled. 70 out of 90 met the eligibility criteria and 60 participants fulfilled all requirements. Participants were randomly allocated to four different groups. The pre-assessment screening was started along with the first trial of chemotherapy. The CBT-based treatment plan was formulated and one session per week was given to each patient for 3 to 4months. Participants’ age range was 18–65 years (M ± SD = 47.51 ± 12.36. Demographic form, DASS, DAS, SWLS, and RSES measures were used. Descriptive, t-test, and repeated measure ANOVA statistics were used to investigate the findings.ResultsResults indicated significant mean difference on the variable of depression, anxiety and stress across four conditions (i.e. F (2, 56) = 39.55, p < .000, η2 = .679; F(2,56) = 73.32, p < .000, η2 = .797; F(2,56) = 119.77, p < .000, η2 = .865 respectively). On death anxiety significant difference across four conditions was found (F (2,56) = 22.71, p < .000, η2 = .549) with large effect size. Furthermore, findings indicated significant mean difference on the variable of satisfaction with life and self-esteem across four conditions was found (F(2,56) = 22.05, p < .000, η2 = .542; F(2,56) = 36.19, p < .000, η2 = .660) with large effect size.ConclusionIt is concluded that CBT played a very effective role to reduce depression, anxiety, and stress-related psychiatric symptoms. CBT reduces the level of death anxiety and improving the quality of life and level of self-esteem among CPdC.Trial Registration: The study trial was registered in the Thai Clinical Trial Registry-TCTR (TCTR20201113002).

Download Full-text