Self-Harm in Late Life and Subsequent Risk of Dementia

Abstract Background Late-life self-harm (SH) is often linked to depression. However, very few studies have explored the role of other factors and their interaction with depression in the occurrence of late-life SH. The objective of this research was to examine sociodemographic and gender factors associated with non-fatal SH, in older adults with and without antidepressant therapy. Methods We used national longitudinal register data from a total cohort of all Swedish residents aged ≥75 years between 2006-2014 (N=1,413,806). Using personal identity numbers, we linked individuals' data from numerous national registers. We identified all those with at least one episode of non-fatal self-harm (regardless of level of intent to die) and matched 50 controls to each case. A nested case–control design was used to investigate the sociodemographic factors associated with non-fatal SH in the total cohort and among antidepressant users and non-users. Risk factors were analysed in adjusted conditional logistic regression models for the entire cohort and by gender. Results In all, 2242 individuals had at least one episode of a non-fatal SH (980 men and 1262 women). In the total cohort, being married was a protective factor for non-fatal SH in men but not in women. A higher non-fatal SH risk was found in antidepressant users from outside Nordic countries (IRR: 1.44; 95% CI: 1.11-1.86), and in non-users of antidepressants from other Nordic countries (IRR: 1.58; 95% CI: 1.08-2.29). Antidepressant users with higher education had an increased risk of non-fatal SH (IRR: 1.34; 95% CI: 1.12-1.61), in both men and women. Conclusions Being married did not mitigate risk of self-harm in older women. Foreign country of birth and higher education were associated with increased risk of non-fatal SH. Healthcare professionals and social workers must be informed about high-risk groups for suicidal behaviour, and ensure they are adequately monitored both in term of antidepressant therapy and access to psychosocial support.

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What are sociodemographic and gender determinants of non-fatal self-harm in older adults users and non-users of antidepressants? A national population-based study

10.21203/rs.2.20076/v2 ◽

2020 ◽

Author(s):

Khedidja Hedna ◽

Johan Fastbom ◽

Ingmar Skoog ◽

Gunnel Hensing ◽

Margda Waern

Keyword(s):

Higher Education ◽

Older Adults ◽

Late Life ◽

Nordic Countries ◽

Antidepressant Therapy ◽

Factors Associated ◽

Total Cohort ◽

Increased Risk ◽

Self Harm ◽

And Gender

Abstract Background Late-life self-harm (SH) is often linked to depression. However, very few studies have explored the role of other factors and their interaction with depression in the occurrence of late-life SH. The objective of this research was to examine sociodemographic and gender factors associated with non-fatal SH, in older adults with and without antidepressant therapy. Methods We used national longitudinal register data from a total cohort of all Swedish residents aged ≥75 years between 2006-2014 (N=1,413,806). Using personal identity numbers, we linked individuals' data from numerous national registers. We identified all those with at least one episode of non-fatal self-harm (regardless of level of intent to die) and matched 50 controls to each case. A nested case–control design was used to investigate the sociodemographic factors associated with non-fatal SH in the total cohort and among antidepressant users and non-users. Risk factors were analysed in adjusted conditional logistic regression models for the entire cohort and by gender. Results In all, 2242 individuals had at least one episode of a non-fatal SH (980 men and 1262 women). In the total cohort, being married was a protective factor for non-fatal SH in men but not in women. A higher non-fatal SH risk was found in antidepressant users from outside Nordic countries (IRR: 1.44; 95% CI: 1.11-1.86), and in non-users of antidepressants from other Nordic countries (IRR: 1.58; 95% CI: 1.08-2.29). Antidepressant users with higher education had an increased risk of non-fatal SH (IRR: 1.34; 95% CI: 1.12-1.61), in both men and women. Conclusions Being married did not mitigate risk of self-harm in older women. Foreign country of birth and higher education were associated with increased risk of non-fatal SH. Healthcare professionals and social workers must be informed about high-risk groups for suicidal behaviour, and ensure they are adequately monitored both in term of antidepressant therapy and access to psychosocial support.

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Sleep duration trajectory during the transition to adolescence and subsequent risk of non-suicidal self-harm

European Child & Adolescent Psychiatry ◽

10.1007/s00787-021-01768-9 ◽

2021 ◽

Author(s):

Jiao Fang ◽

Yuhui Wan ◽

Xingyan Zhang ◽

Puyu Su ◽

Fangbiao Tao ◽

...

Keyword(s):

Sleep Duration ◽

Transition To Adolescence ◽

Self Harm ◽

Subsequent Risk

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Suicide in patients suffering from late-life anxiety disorders; a comparison with younger patients

International Psychogeriatrics ◽

10.1017/s1041610215000125 ◽

2015 ◽

Vol 27 (7) ◽

pp. 1197-1205 ◽

Cited By ~ 14

Author(s):

R. C. Oude Voshaar ◽

D. C. van der Veen ◽

N. Kapur ◽

I. Hunt ◽

A. Williams ◽

...

Keyword(s):

Anxiety Disorder ◽

Anxiety Disorders ◽

Older Patients ◽

Living Arrangement ◽

Late Life ◽

The Elderly ◽

Depressive Illness ◽

Younger Patients ◽

History Of ◽

Self Harm

ABSTRACTBackground:Anxiety disorders are assumed to increase suicide risk, although confounding by comorbid psychiatric disorders may be one explanation. This study describes the characteristics of older patients with an anxiety disorder who died by suicide in comparison to younger patients.Method:A 15-year national clinical survey of all suicides in the UK (n = 25,128). Among the 4,481 older patients who died by suicide (≥ 60 years), 209 (4.7%) suffered from a primary anxiety disorder, and 533 (11.9%) from a comorbid anxiety disorder. Characteristics of older (n = 209) and younger (n = 773) patients with a primary anxiety disorder were compared by logistic regression adjusted for sex and living arrangement.Results:Compared to younger patients, older patients with a primary anxiety disorder were more often males and more often lived alone. Although 60% of older patients had a history of psychiatric admissions and 50% of deliberate self-harm, a history of self-harm, violence, and substance misuse was significantly less frequent compared to younger patients, whereas physical health problems and comorbid depressive illness were more common. Older patients were prescribed significantly more psychotropic drugs and received less psychotherapy compared to younger patients.Conclusion:Anxiety disorders are involved in one of every six older patients who died by suicide. Characteristics among patients who died by suicide show severe psychopathology, with a more prominent role for physical decline and social isolation compared to their younger counterparts. Moreover, treatment was less optimal in the elderly, suggesting ageism. These results shed light on the phenomenon of suicide in late-life anxiety disorder and suggest areas where prevention efforts might be focused.

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What are the sociodemographic and gender determinants of non-fatal self-harm in older adult users and non-users of antidepressants? A national population-based study

10.21203/rs.2.20076/v3 ◽

2020 ◽

Author(s):

Khedidja Hedna ◽

Johan Fastbom ◽

Ingmar Skoog ◽

Gunnel Hensing ◽

Margda Waern

Keyword(s):

Older Adults ◽

Late Life ◽

Sociodemographic Factors ◽

Nordic Countries ◽

Men And Women ◽

Factors Associated ◽

Total Cohort ◽

Increased Risk ◽

Self Harm ◽

And Gender

Abstract Background Late-life self-harm (SH) is often linked to depression. However, very few studies have explored the role of other factors and their interaction with depression in the occurrence of late-life SH. The objective of this research was to examine sociodemographic and gender factors associated with non-fatal SH, in older adults with and without antidepressant therapy.Methods We used national longitudinal register data from a total cohort of all Swedish residents aged ≥75 years between 2006-2014 (N=1,413,806). Using personal identity numbers, we linked individuals' data from numerous national registers. We identified all those with at least one episode of non-fatal self-harm (regardless of level of intent to die) and matched 50 controls to each case. A nested case–control design was used to investigate sociodemographic factors associated with non-fatal SH in the total cohort and among antidepressant users and non-users. Risk factors were analysed in adjusted conditional logistic regression models for the entire cohort and by gender.Results In all, 2242 individuals had at least one episode of a non-fatal SH (980 men and 1262 women). Being unmarried was a risk factor for non-fatal SH in men but not in women. Among users of antidepressants, higher non-fatal SH risk was observed in those born outside the Nordic countries (IRR: 1.44; 95% CI: 1.11–1.86), whereas in AD non-users increased risk was seen in those from Nordic countries other than Sweden (IRR: 1.58; 95% CI: 1.08–2.29). Antidepressant users with higher education had an increased risk of non-fatal SH (IRR: 1.34; 95% CI: 1.12–1.61), in both men and women. Conclusions Foreign country of birth was associated with increased risk for non-fatal SH in older adults with and without AD therapies. Being married was a protective factor for non-fatal SH in men. The complex association between sociodemographic factors and use of antidepressants in the occurrence of self-harm in older men and women indicates the need for multifaceted tailored preventive strategies including healthcare and social services alike.

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