Examining the impact of a penicillin allergy skin testing brochure on inpatient perceptions: a pre-post intervention study

Author(s):  
Mikaela Brown ◽  
Joy Uzoma ◽  
Ryan Vansice ◽  
Karlie Mahan ◽  
Kelly M. Conn ◽  
...  
2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S351-S351
Author(s):  
Mikaela Brown ◽  
Joy Uzoma ◽  
Ryan P VanSice ◽  
Kelly M Conn ◽  
Allison Ramsey ◽  
...  

Abstract Background Despite the negative implications associated with a penicillin (PCN) allergy label, less than 0.1% of ~25 million subjects with PCN allergy undergo a PCN skin testing (PST). There is a lack of data assessing patient knowledge and attitude about PCN allergy and PST. The purpose of this study was to evaluate the impact of an educational brochure on knowledge and perception of PST in adult inpatients with a PCN allergy label. Methods This was a pre-post intervention study conducted at a 528-bed community teaching hospital between June 2016 and March 2019. An electronic medical record was used to identify adult inpatients with an active PCN allergy. Participants completed a pre-brochure survey to assess demographic characteristics and baseline knowledge of PCN allergy and PST. Individuals then read an educational brochure, returned it to study personnel and were provided a post-brochure survey to complete. The primary and secondary outcomes of knowledge and perception were measured based on the level of agreement with statements about PCN allergies and PST using a 5-point Likert scale. McNemar’s test was used to compare responses for those who agreed vs. did not agree to knowledge statements. Results Among 125 patients approached, 101 completed the survey (80.8%). Patients were predominantly female (66.3%), >65 years of age (42.6%), Caucasian (78.2%) and completed high school or beyond (81.2%). The minority of patients (40.6%) previously heard about PST while 25.7% agreed they had previous discussions about PST with a healthcare provider. Only 24.8% agreed that people can outgrow a PCN allergy at baseline; however, after reading the brochure, this percent tripled (77.2%) (P < 0.01). Among 56 participants who disagreed that PST would be helpful for them at baseline, 30 subsequently agreed with this statement on the post-brochure survey (P < 0.001). Post-brochure, 86.1% indicated they felt better informed about PST. Despite this, 34.7% indicated they would be scared to use PCN again if future PST results were negative. Conclusion An educational brochure improved general knowledge of PCN allergy and PST, including subject report of feeling more informed. Although the brochure successfully educated patients, gaps remain regarding how individuals will personally apply this new information. Disclosures All authors: No reported disclosures.


2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S266-S267 ◽  
Author(s):  
Christopher Kovacs ◽  
Vasilios Athans ◽  
David Lang ◽  
Ronald Sobecks ◽  
Lisa Rybicki ◽  
...  

2007 ◽  
Vol 27 (4) ◽  
pp. 542-545 ◽  
Author(s):  
Jeremy A Schafer ◽  
Noe Mateo ◽  
Garry L Parlier ◽  
John C Rotschafer

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e027945
Author(s):  
Celina Lichtl ◽  
Kayvan Bozorgmehr

ObjectiveMeasuring the effect of introducing a walk-in clinic on ambulatory care sensitive (ACS) hospitalisations among asylum seekers in a large state reception- and registration centre.Design and settingPre–post intervention study using anonymous account data from a university hospital functioning as referral facility for a state reception- and registration centre in the third largest German federal state.ParticipantsWe included all asylum seekers residing in the reception centre and admitted to the referral hospital between 2015 to 2017.InterventionsEstablishment of an interdisciplinary walk-in clinic in the reception centre (02/2016).Main outcome measuresInternational lists for ACS conditions for both adults and children were adapted and used to calculate the prevalence of ACS conditions among the population (primary outcome measure). The impact of the intervention on the outcome was analysed using a segmented Poisson regression to calculate incidence-rate ratios with respective 95% CIs, adjusted for age, sex and admission.ResultsThe prevalence of ACS hospitalisations changed over time, as did the effect of age, sex and quarter of admission. Introducing the walk-in clinic reduced the prevalence of ACS hospitalisations among asylum seekers compared with the period before establishment of the clinic (incidence-rate ratios (IRR)=0.80 (0.65 to 1.00), p=0.054), but the effect was attenuated after adjustment for time trends. The average difference in prevalence of ACS hospitalisations compared with the period before establishment of the clinic, corrected for pre-existing time trends, age and sex of asylum seekers was IRR=1.03 ((0.69 to 1.55), p=0.876).ConclusionsA walk-in clinic in reception centres may be effective to reduce ACS hospitalisations, but our study could not prove evidence for a measurable effect after full adjustment for time trends. Further research, ideally with parallel control groups, is required to establish evidence for the effectiveness of walk-in clinics in reception centres on reducing ACS hospitalisations.


2018 ◽  
Vol 6 (6) ◽  
pp. 2033-2040 ◽  
Author(s):  
Mary L. Staicu ◽  
Anne Marie Holly ◽  
Kelly M. Conn ◽  
Allison Ramsey

1997 ◽  
Vol 27 (4) ◽  
pp. 199-202 ◽  
Author(s):  
Mubina Agboatwalla ◽  
Dure Samin Akram

A prospective community-based intervention study was conducted in a slum area of Karachi, Pakistan, with the objective of evaluating the impact of health education on the knowledge of mothers. One hundred and fifty households were studied in the intervention and the same in the non-intervention group. The post intervention knowledge scores of the mothers showed a significant difference of P < 0.05. Nearly 50.7% mothers in the intervention group knew of at least four diseases against which vaccination is given as compared to the non-intervention group ( P < 0.05). Similarly, mothers in the intervention group were more aware about the advantages of breast feeding, signs of dehydration, measures for prevention of measles and tuberculosis as compared to the non-intervention group ( P < 0.05). Finally, a comparison was made between the pre- and post-intervention scores between the two groups. The score in the non-intervention group changed from 11.5 to 16.1 ( P > 0.05) as compared to the intervention group in which it changed from 10.2 to 32.2 ( P < 0.05).


Author(s):  
Ameen M. Almohammadi ◽  
Huda M. Al-Dhahri ◽  
Shroug H. Al-Harbi

Aims: There are series of medical errors that can be prevented by taking precautions.             Therefore, the study evaluates the impact of the electronic prescribing system on prescription errors. Study Design:  A pre-post study design was conducted. Place and Duration of Study: The study was conducted at outpatient pharmacy services of a teaching hospital in Jeddah city. Methodology: Prescriptions were evaluated for the presence of the essential prescription elements such as patient information, drug name, dose, frequency, strength, and other prescription completeness parameters. Results: In the pre-intervention study, 1182 handwritten prescriptions were evaluated, and 6627 errors were detected from these prescriptions. The length of the pre-and post-intervention period was two weeks each. The most prevalent prescribing errors were that of medications written without defined dosage forms were recorded 1653 (55.90%) time followed by prescriptions written by trade names 1493 (22.5%), without route of administration 1266 (19.1%), and without specified duration 1009 (15.2%). However, 1512 prescriptions were evaluated in the post-intervention study, among which 339 errors were detected. The errors included prescriptions written without diagnosis (5.09%), or without doctor’s name or stamp (1.52%), written by trade names (4.49%), without defined dosage forms (4.29%), and without specified duration (2.84%). Conclusion: The study concluded that E-prescribing eliminated prescription errors that resulted from handwritten prescriptions.


2021 ◽  
pp. 001857872110468
Author(s):  
Hanna M. Harper ◽  
Michael Sanchez

Objective: To describe the impact of pharmacy driven penicillin allergy assessments on de-labeling penicillin allergies and antibiotic streamlining opportunities for hospitalized patients. Design: Multi-center, retrospective case-series study. Setting: A health system of 4 non-teaching hospitals. Participants: Patients aged 18 years and older with a physician order for a pharmacist penicillin allergy assessment. Exclusion criteria consisted of patients with anaphylaxis or a type II penicillin allergy, anaphylaxis of any cause within 4 weeks, refusal of penicillin allergy skin test (PAST), antihistamine use within 24 hours, penicillin intolerance, immunosuppression or immunosuppressive medications, or skin conditions that could interfere with PAST. Interventions: The primary endpoint evaluated the number of de-labeled penicillin allergies after pharmacists provided penicillin allergy assessments. Secondary endpoints evaluated the percent of patients with antibiotics deescalated to beta-lactam antibiotics and classification of notable interventions made by pharmacists. Measurements and Main Results: There were 35 patients who met inclusion criteria. Twenty-four patients underwent both penicillin allergy skin testing and oral (PO) amoxicillin challenge. Five patients had allergies de-labeled only after a pharmacist interview. Four patients received only the PO amoxicillin challenge and 2 patients received only PAST. Penicillin allergies were de-labeled from the electronic health record (EHR) in 31 (89%) patients despite all testing negative for a penicillin allergy from PAST or a PO amoxicillin challenge. Four patients had the allergy re-added to the chart on subsequent admissions. No patients experienced a reaction from PAST, PO amoxicillin challenge, or subsequent beta-lactam antibiotics. Twenty-eight (80%) patients had their antibiotic therapy changed as a result of the allergy assessment. Seventeen patients were de-escalated onto beta-lactam antibiotics and aztreonam was stopped in 6 patients. Conclusion: Results from this study suggests that pharmacists expanding their scope of practice with PAST is a safe and effective allergy de-labeling tool. Pharmacist-driven penicillin allergy assessments could provide antibiotic cost savings and avoid aztreonam use. The study supports the need to emphasize education for patients and caretakers regarding allergy testing results to avoid relabeling in future hospital visits.


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