[P3-562]: HIGH PREVALENCE OF VASCULAR AND METABOLIC RISK FACTORS AMONG DOWN SYNDROME PATIENTS WITH ALZHEIMER's DISEASE: A SURVEY REPORT OF THE NATIONAL DOWN SYNDROME REGISTRY (DS-CONNECT)

2017 ◽  
Vol 13 (7S_Part_24) ◽  
pp. P1193-P1194
Author(s):  
Jonathan M. Artal ◽  
Ayesha Z. Sherzai ◽  
Dean Sherzai
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Survey Report ◽  
High Prevalence

scholarly journals Metabolic risk factors, but not vascular lesions and β‐amyloid, are associated with functional connectivity across the Alzheimer’s disease spectrum

2020 ◽  
Vol 16 (S5) ◽  
Author(s):  
Theresa Köbe ◽  
Malo Gaubert ◽  
Catharina Lange ◽  
Antoine Garnier‐Crussard ◽  
Salma Bougacha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Functional Connectivity ◽  
Metabolic Risk Factors ◽  
Vascular Lesions ◽  
Metabolic Risk ◽  
Disease Spectrum ◽  
Β Amyloid

scholarly journals Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment

2015 ◽  
Vol 6 (4) ◽  
pp. 282 ◽  
Author(s):  
Sasanka Chakrabarti ◽  
Vineet Kumar Khemka ◽  
Anindita Banerjee ◽  
Gargi Chatterjee ◽  
Anirban Ganguly ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Sporadic Alzheimer’S Disease

scholarly journals High Prevalence of Cardio-Metabolic Risk Factors in a Young Urban Sri-Lankan Population

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e31309 ◽  
Author(s):  
Mahen Wijesuriya ◽  
Martin Gulliford ◽  
Judith Charlton ◽  
Laksha Vasantharaja ◽  
Giancarlo Viberti ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Risk Factors ◽  
Sri Lankan ◽  
Metabolic Risk ◽  
High Prevalence

The impact of risk factors of Alzheimer's disease in the Down syndrome

2003 ◽  
Author(s):  
Marcella Folin ◽  
Silvia Baiguera ◽  
Maria Conconi ◽  
Tecla Pati ◽  
Claudio Grandi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Down Syndrome ◽  
The Impact

scholarly journals Metabolic Risk Factors of Alzheimer’s Disease, Dementia with Lewy Bodies, and Normal Elderly: A Population-Based Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Chih-Kuang Cheng ◽  
Yu-Chien Tsao ◽  
Yuan-Chih Su ◽  
Fung-Chang Sung ◽  
Hsu-Chih Tai ◽  
...  
Keyword(s):  
Risk Factors ◽  
Alzheimer’S Disease ◽  
Ischemic Stroke ◽  
Lower Risk ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies ◽  
Population Based ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Population Based Study

Background. Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) share many risk factors. Evidence suggests that metabolic risk factors are important to AD; however, their association with DLB is unclear. The risk of cardiovascular diseases (CVD) associated with AD and DLB is also uncertain. Thus, this nationwide, population-based study was designed to evaluate the metabolic and CVD risks in AD and DLB. Materials and Methods. Data were obtained from the Taiwan National Health Insurance Research Database. AD patients, DLB patients, and normal control (NC) individuals from 1996 to 2013 were enrolled for risk assessment. Results. In total, 7544 NC individuals, 1324 AD patients, and 562 DLB patients were enrolled. Participants with one or more metabolic risk factors had significantly higher odds of AD or DLB. No significant differences in metabolic risk factors were observed between DLB and AD patients. AD patients had a lower risk of CVD (aHR = 0.67, 95% CI = 0.59–0.76, p value < 0.001) and coronary artery disease (CAD) (aHR = 0.59, 95% CI = 0.51–0.69, p value < 0.001) than NC. DLB patients had a higher risk of ischemic stroke (aHR = 2.27, 95% CI = 1.68–3.06, p value < 0.001) than NC. Conclusion. Metabolic risk factors are important in AD and DLB. Patients with AD might have a lower risk of CAD and ischemic strokes. Patients with DLB might have a higher risk of ischemic stroke.

High prevalence of cardio-metabolic risk factors among adolescents with intellectual disability

2009 ◽  
Vol 98 (5) ◽  
pp. 853-859 ◽  
Author(s):  
Eva Flygare Wallén ◽  
Maria Müllersdorf ◽  
Kyllike Christensson ◽  
Gunilla Malm ◽  
Örjan Ekblom ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intellectual Disability ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
High Prevalence

scholarly journals Physical activity, BMI and metabolic risk in Portuguese adolescents

2016 ◽  
Vol 18 (1) ◽  
pp. 103 ◽  
Author(s):  
Fernanda Karina dos Santos ◽  
Thayse Natacha Queiroz Ferreira Gomes ◽  
Michele Caroline de Souza ◽  
Raquel Nichele Chaves ◽  
Daniel Monteiro de Vilhena Santos ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Hdl Cholesterol ◽  
Normal Weight ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Positive Role ◽  
High Prevalence ◽  
Portuguese Adolescents

DOI: http://dx.doi.org/10.5007/1980-0037.2016v18n1p103 It has been reported, in the last decades, a significant decrease in physical activity (PA) levels, with a consequent increase in obesity and metabolic risk factors among youth. The aims of this study were to describe PA levels, the prevalence of overweight/obesity and metabolic risk factors, and to examine the association between PA and body mass index (BMI) with metabolic risk among Portuguese youth. The sample comprises 212 Portuguese adolescents (12-16 years old). Height and weight were measured. PA was estimated with the Bouchard questionnaire (3 days recall), as well as with the use of a pedometer (used for 5 consecutive days). Metabolic risk factors comprised fasting glucose, triglycerides, HDL-cholesterol, systolic blood pressure and waist circumference. Subjects were classified as normal weight, overweight or obese according to BMI; the maturational status was indirectly estimated with the maturity offset procedure. A continuous metabolic risk score was computed (zMR) and PA values were divided into tertiles. Qui-square test, t-test and ANOVA were used in statistical analyses. SPSS 18.0 and WinPepi softwares were used and p<0.05. A moderate to high prevalence of overweight/obesity and HDL-cholesterol was found, as well as a high prevalence of high blood pressure and low to moderate PA levels among Portuguese youth. The relationship between BMI and zMR showed that obese adolescents have higher zMR when compared to normal weight or overweight adolescents. This finding suggests that increased levels of PA and reduction in the prevalence of overweight/obesity may have a positive role against the development of metabolic risk factors.

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