scholarly journals Hydrogen sulfide toxicity in the gut environment: Meta-analysis of sulfate-reducing and lactic acid bacteria in inflammatory processes

2021 ◽  
Vol 27 ◽  
pp. 55-69 ◽  
Author(s):  
Dani Dordević ◽  
Simona Jančíková ◽  
Monika Vítězová ◽  
Ivan Kushkevych
Keyword(s):  
Hydrogen Sulfide ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Meta Analysis ◽  
Sulfate Reducing ◽  
Sulfide Toxicity ◽  
Inflammatory Processes

scholarly journals Possible methods for evaluation of hydrogen sulfide toxicity against lactic acid bacteria

2019 ◽  
Vol 9 (4) ◽  
pp. 4066-4069 ◽  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Hydrogen Sulfide ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Bowel Disease ◽  
Inhibitory Concentration ◽  
Agar Plate ◽  
Intestinal Microbiome ◽  
Sulfate Reducing ◽  
Inflammatory Bowel

An integral part of the intestinal microbiota is undoubtedly formed by lactic acid bacteria (LAB). Their presence in the digestive tract is essential for its proper functioning. During inflammatory bowel disease, such as ulcerative colitis (UC), LAB occurrence is reduced while sulfate-reducing bacteria (SRB) occur widely in the intestine resulting in an increase of their metabolite, hydrogen sulfide. Inhibitory concentration and mechanism of action of hydrogen sulfide on LAB are not fully known yet. The aim of this paper is to find the proper testing methods for evaluation of the interaction between hydrogen sulfide and lactic acid bacteria, including minimal inhibitory concentration (MIC) determination. Spectrophotometric, colorimetric, agar plate methods and combination of these methods were tested. Thousands of people from all over the world are affected by inflammatory bowel disease every year. The gained results could help to understand and improve the stability of intestinal microbiome, improve the treatment of bowel inflammation diseases, or prevent bowel disease altogether

scholarly journals Hydrogen Sulfide Effects on the Survival of Lactobacilli with Emphasis on the Development of Inflammatory Bowel Diseases

Biomolecules ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 752 ◽  
Author(s):  
Ivan Kushkevych ◽  
Věra Kotrsová ◽  
Dani Dordević ◽  
Leona Buňková ◽  
Monika Vítězová ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Growth Parameters ◽  
Sulfate Reducing Bacteria ◽  
Lactobacillus Species ◽  
Pcr Analysis ◽  
Isolation And Identification ◽  
Sulfate Reducing ◽  
Reducing Bacteria

The gut microbiota is a complex component of humans that depends on diet, host genome, and lifestyle. The background: The study purpose is to find relations between nutrition, intestinal lactic acid bacteria (LAB) from various environments (human, animal intestine, and yogurt) and sulfate-reducing microbial communities in the large intestine; to compare kinetic growth parameters of LAB; and to determine their sensitivity to different concentration of hydrogen sulfide produced by intestinal sulfate-reducing bacteria. Methods: Microbiological (isolation and identification), biochemical (electrophoresis), molecular biology methods (DNA isolation and PCR analysis), and statistical processing (average and standard error calculations) of the results were used. The results: The toxicity of hydrogen sulfide produced by sulfate-reducing bacteria, the survival of lactic acid bacteria, and minimal inhibitory concentrations (MIC) were determined. The measured hydrogen sulfide sensitivity values were the same for L. paracasei and L. reuteri (MIC > 1.1 mM). In addition, L. plantarum and L. fermentum showed also a similar sensitivity (MIC > 0.45 mM) but significantly (p < 0.05) lower than L. reuteri and L. paracasei (1.1 > 0.45 mM). L. paracasei and L. reuteri are more sensitive to hydrogen sulfide than L. fermentum and L. plantarum. L. pentosus was sensitive to the extremely low concentration of H2S (MIC > 0.15 mM). Conclusions: The Lactobacillus species were significantly sensitive to hydrogen sulfide, which is a final metabolite of intestinal sulfate-reducing bacteria. The results are definitely helpful for a better understanding of complicated interaction among intestinal microbiota and nutrition.

A meta‐analysis examining lactic acid bacteria inoculants for maize silage: Effects on fermentation, aerobic stability, nutritive value and livestock production

2019 ◽  
Vol 74 (4) ◽  
pp. 596-612 ◽  
Author(s):  
Alexandre Bernardi ◽  
Carla J. Härter ◽  
Antonio W. L. Silva ◽  
Ricardo A. Reis ◽  
Carlos H. S. Rabelo
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Nutritive Value ◽  
Meta Analysis ◽  
Livestock Production ◽  
Maize Silage ◽  
Aerobic Stability

A meta-analysis on the effectiveness of homofermentative and heterofermentative lactic acid bacteria for corn silage

2018 ◽  
Vol 125 (6) ◽  
pp. 1655-1669 ◽  
Author(s):  
J.E. Blajman ◽  
R.B. Páez ◽  
C.G. Vinderola ◽  
M.S. Lingua ◽  
M.L. Signorini
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Meta Analysis ◽  
Corn Silage

scholarly journals The effects of lactic acid bacteria and yeasts as probiotics on the growth performance, relative organ weight, blood parameters, and immune responses of broiler: A meta-analysis

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 183
Author(s):  
Osfar Sjofjan ◽  
Danung Nur Adli ◽  
Rakhmad Perkasa Harahap ◽  
Anuraga Jayanegara ◽  
Dicky Tri Utama ◽  
...  
Keyword(s):  
Immune Response ◽  
Body Weight ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Growth Performance ◽  
Meta Analysis ◽  
Blood Parameters ◽  
Organ Weight ◽  
Published Data ◽  
Relative Organ Weight

Introduction: The number of publications in Scopus on this topic increased from less than 50 in 1995 to more than 250 in 2015. In other hand, inconsistency in results about the correlation between yeast and lactic acid bacteria as probiotics has been evident since the early publications on use in broilers. Methods: A meta-analysis was conducted to determine relationship between lactic acid bacteria and yeast as probiotics to broiler diets on the growth performance, relative organ weight, blood parameters, and immune response of the broiler.  A database was designed based on published data that reported the use of probiotics on the broiler. The method used for selecting articles was based on the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) method. Articles selected were taken from PubMed, Web of science, Scopus, Google Scholar, and Science direct databases as well as individual. Results: The final database consists of 49 in vivo articles, 93 studies, and 225 treatments. The analysis statement in the system was a PROC MIXED procedure of SAS software. The level of probiotic increased (p <0.001) body weight, body weight gain, and feed intake of broiler. There was a reduction (p <0.01) on feed conversion ratio and mortality on the level probiotic given to broiler. Supplementation of probiotics in broiler diet increased (p <0.001) the weight of liver, spleen, gizzard, bursa of fabricius and carcass yield, while reduced (p<0.001) abdominal fat weight. The probiotic given increased the total of red and white blood cells (both at p < 0.001) but did not affect lymphocyte.  Discussion: It can be concluded the yeast act as supporting agent that serves lactic acid bacteria as probiotic increases the growth performance, relative organ weight, blood parameters, and immune response of the broiler.

scholarly journals Effect of Homofermentative and Heterofermentative Lactic Acid Bacteria on the Quality and Aerobic Stability of Silage : Meta-Analysis

2014 ◽  
Vol 34 (4) ◽  
pp. 247-253 ◽  
Author(s):  
Sangbuem Cho ◽  
Jung Sun Kang ◽  
Kyung Jin Cho ◽  
Kang Hee Lee ◽  
Chan Ho Kwon ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Meta Analysis ◽  
Aerobic Stability

scholarly journals Systematic review and meta-analysis: the effects of fermented milk with Bifidobacterium lactis CNCM I-2494 and lactic acid bacteria on gastrointestinal discomfort in the general adult population

2016 ◽  
Vol 10 (1) ◽  
pp. 74-88 ◽  
Author(s):  
Jacqui Eales ◽  
Peter Gibson ◽  
Peter Whorwell ◽  
John Kellow ◽  
Ann Yellowlees ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Meta Analysis ◽  
Adult Population ◽  
Fermented Milk ◽  
Sensitivity Analyses ◽  
Bifidobacterium Lactis ◽  
Gastrointestinal Discomfort ◽  
General Adult Population ◽  
Meta Analyses

Background: It has been suggested that probiotics may improve gastrointestinal discomfort. Not all probiotics exhibit the same effects and consequently meta-analyses on probiotics should be confined to well-defined strains or strain combinations. The aim of this study was to evaluate the effectiveness of a probiotic fermented milk (PFM) that includes Bifidobacterium lactis ( B. lactis) CNCM I-2494 and lactic acid bacteria on gastrointestinal discomfort in the general adult population. Methods: Double-blind randomized controlled trials in the general adult population comparing PFM with a control dairy product for at least 4 weeks were searched from multiple literature databases (up to February 2015). Meta-analyses using random-effects models, with individual participant data were undertaken to calculate an odds ratio (OR) or standard mean difference (SMD), with a 95% confidence interval (CI). Results: The search strategy identified 12,439 documents. Overall, three trials with a total of 598 adults (female = 96.5%) met the inclusion criteria. Consumption of the PFM product was associated with a significant improvement in overall gastrointestinal discomfort compared with the control product (OR = 1.48; 95% CI 1.07–2.05), with a number needed to treat (NNT) of 10.24 (95% CI 5.64–55.93). PFM was also superior to the control in reducing digestive symptoms, as measured using a composite score (SMD = −0.21; 95% CI −0.37 to −0.05). Sensitivity analyses produced similar results, and the heterogeneity between studies was minimal. Conclusions: This meta-analysis shows that the consumption of PFM with B. lactis CNCM I-2494 and lactic acid bacteria is associated with a modest but consistent and significant improvement of outcomes related to gastrointestinal discomfort in healthy adults.

scholarly journals The role of homofermentative and heterofermentative lactic acid bacteria for alfalfa silage: a meta-analysis

2020 ◽  
Vol 158 (1-2) ◽  
pp. 107-118
Author(s):  
J. E. Blajman ◽  
G. Vinderola ◽  
R. B. Páez ◽  
M. L. Signorini
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Nutritive Value ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Positive Effects ◽  
Aerobic Stability ◽  
Alfalfa Silage ◽  
Silage Inoculants

AbstractLactic acid bacteria (LAB) are usually employed as alfalfa silage inoculants to obtain high-quality feed for animal husbandry. However, the effects of these inoculants are still unclear and need to be studied extensively. Therefore, the objective of this meta-analysis was to quantitatively summarize published research studies that assess the effects of homofermentative (HoLAB) and heterofermentative lactic acid bacteria (HeLAB) on fermentation parameters, nutritive value, microbiological composition and aerobic stability of alfalfa silage. PubMed, ScienceDirect and Scopus have been screened for articles published from 1980 to 2018. The criteria for inclusion were: randomized and controlled trials using alfalfa silage and published in peer-reviewed journals. It was found that inoculation with LAB decreased silage pH, neutral detergent fibre, acid detergent fibre and ammoniacal nitrogen, while it increased dry matter and crude protein compared to control in the pooled raw mean difference random-effect model. Additionally, LAB inoculation decreased acetate, propionate, ethanol and butyrate concentrations, whereas it increased lactate. In addition, inoculants reduced the counts of yeasts and moulds. Lastly, LAB inoculation improved aerobic stability. To the best of our knowledge, this is the first meta-analysis that aims at comparing the application of HoLAB and HeLAB for alfalfa silage. In the pool estimate, positive effects attributable to the application of microbial silage inoculants were found in most of the evaluated parameters; supporting the importance of applying both types of inoculants to improve forage preservation for the livestock industry.

Effects of different lactic acid bacteria groups and fibrolytic enzymes as additives on silage quality: A meta-analysis

2021 ◽  
Vol 14 ◽  
pp. 100654
Author(s):  
Agung Irawan ◽  
Ahmad Sofyan ◽  
Roni Ridwan ◽  
Hasliza Abu Hassim ◽  
Adib Norma Respati ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Meta Analysis ◽  
Fibrolytic Enzymes ◽  
Silage Quality
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