Numerical analysis of pulsatile blood flow and vessel wall mechanics in different degrees of stenoses

2007 ◽  
Vol 40 (16) ◽  
pp. 3715-3724 ◽  
Author(s):  
M.X. Li ◽  
J.J. Beech-Brandt ◽  
L.R. John ◽  
P.R. Hoskins ◽  
W.J. Easson
2016 ◽  
Vol 2016 ◽  
pp. 1-16
Author(s):  
Qinghui Zhang ◽  
Yufeng Zhang ◽  
Yi Zhou ◽  
Kun Zhang ◽  
Kexin Zhang ◽  
...  

This paper presents an ultrasound simulation model for pulsatile blood flow, modulated by the motion of a stenosed vessel wall. It aims at generating more realistic ultrasonic signals to provide an environment for evaluating ultrasound signal processing and imaging and a framework for investigating the behaviors of blood flow field modulated by wall motion. This model takes into account fluid-structure interaction, blood pulsatility, stenosis of the vessel, and arterial wall movement caused by surrounding tissue’s motion. The axial and radial velocity distributions of blood and the displacement of vessel wall are calculated by solving coupled Navier-Stokes and wall equations. With these obtained values, we made several different phantoms by treating blood and the vessel wall as a group of point scatterers. Then, ultrasound echoed signals from oscillating wall and blood in the axisymmetric stenotic-carotid arteries were computed by ultrasound simulation software, Field II. The results show better consistency with corresponding theoretical values and clinical data and reflect the influence of wall movement on the flow field. It can serve as an effective tool not only for investigating the behavior of blood flow field modulated by wall motion but also for quantitative or qualitative evaluation of new ultrasound imaging technology and estimation method of blood velocity.


Author(s):  
Jing Wang ◽  
Suzie Brown ◽  
Stephen W. Tullis

The aorta is the largest artery in humans, stemming from the left ventricle of the heart and stretching down to the abdomen. It is responsible for distributing oxygenated blood to the rest of the body during each cardiac cycle. The pulsatile blood flow is complex in nature and has been previously modeled computationally in an effort to understand its effect on cardiovascular diseases and medical device design interaction [4,8–9]. However, the majority of these models either treat the vessel wall as rigid or have significantly simplified geometries, which from a physiological perspective are not true of large vessels such as the aorta. Here, the complex mechanical interaction between pulsatile blood flow and wall dynamics in the aortic arch is investigated using geometry adopted directly from CT images.


2012 ◽  
Vol 55 (13-14) ◽  
pp. 3763-3773 ◽  
Author(s):  
Tzu-Ching Shih ◽  
Tzyy-Leng Horng ◽  
Huang-Wen Huang ◽  
Kuen-Cheng Ju ◽  
Tzung-Chi Huang ◽  
...  

2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
W Schiller ◽  
K Spiegel ◽  
T Schmid ◽  
H Rudorf ◽  
S Flacke ◽  
...  

2005 ◽  
Vol 6 (2) ◽  
pp. 65 ◽  
Author(s):  
Marc Gerdisch ◽  
Thomas Hinkamp ◽  
Stephen D. Ainsworth

<P>Background: Use of the interrupted coronary anastomosis has largely been abandoned in favor of the more rapid continuous suturing technique. The Coalescent U-CLIP anastomotic device allows the surgeon to create an interrupted distal anastomosis in the same amount of time that it would take to create a continuous anastomosis. This acute bovine study examined the effect of the anastomotic technique on blood flow and vessel wall function. </P><P>Methods: End-to-side coronary anastomoses were created in an open chest bovine model using the left and right internal thoracic arteries and the left anterior descending coronary artery. All other variables except suturing technique were carefully controlled. In each animal, one anastomosis was completed using a continuous suturing technique and the other was performed in an interrupted fashion using the Coalescent U-CLIP anastomotic device. Volumetric flow curves through each graft were analyzed using key indicators of anastomotic quality, and anastomotic compliance was evaluated using intravascular ultrasound. Luminal castings were created of each vessel to examine the interior surface of each anastomosis for constrictions and deformities. </P><P>Results: The interrupted anastomoses created with the Coalescent U-CLIP anastomotic device showed significant differences with respect to anastomotic compliance, pulsatility index, peak flow, and percentage of diastolic flow. The cross-sectional area and degree of luminal deformity were also different for the two suturing techniques. </P><P>Conclusions: In this acute bovine model, interrupted coronary anastomoses demonstrated superior geometric consistency and greater physiologic compliance than did continuously sutured anastomoses. The interrupted anastomosis also caused fewer disturbances to the flow waveform, behaving similarly to a normal vessel wall. The combination of these effects may influence both acute and long-term patency of the coronary bypass grafts.</P>


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