Statistical modeling and optimization for enhanced whole-cell biotransformation synthesis of 2-O-α-d-glucopyranosyl-l-ascorbic acid from maltose and l-ascorbic acid by Aspergillus niger capable of producing α-glucosidase

A novel biocatalytic system for the synthesis of the industrially relevant C2 chemicals (e.g., ethylene glycol (3)) from formaldehyde (1) was established. The biocatalytic system consisted of a newly discovered...

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Session 1A: Statistical Modeling and Optimization Methodologies

IEEE/ACM International Conference on Computer Aided Design, 2004. ICCAD-2004. ◽

10.1109/iccad.2004.1382532 ◽

2004 ◽

Keyword(s):

Statistical Modeling ◽

Modeling And Optimization

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New fungi for whole-cell biotransformation of carvone enantiomers. Novel p-menthane-2,8,9-triols production

Applied Catalysis A General ◽

10.1016/j.apcata.2013.08.034 ◽

2013 ◽

Vol 468 ◽

pp. 88-94 ◽

Cited By ~ 10

Author(s):

Fátima M. Nunes ◽

Gabriel F. dos Santos ◽

Natália N. Saraiva ◽

Marília A. Trapp ◽

Marcos C. de Mattos ◽

...

Keyword(s):

Whole Cell ◽

Whole Cell Biotransformation

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Enhancing or Inhibitory Effect of Fruit or Vegetable Bioactive Compound on Aspergillus niger and A. oryzae

Journal of Fungi ◽

10.3390/jof8010012 ◽

2021 ◽

Vol 8 (1) ◽

pp. 12

Author(s):

Gülru Bulkan ◽

Sitaresmi Sitaresmi ◽

Gerarda Tania Yudhanti ◽

Ria Millati ◽

Rachma Wikandari ◽

...

Keyword(s):

Ascorbic Acid ◽

Aspergillus Niger ◽

Bioactive Compounds ◽

Ellagic Acid ◽

Microbial Growth ◽

Biomass Yield ◽

Antimicrobial Effect ◽

Bioactive Compound ◽

Inhibitory Effect ◽

Processing Wastes

Fruit and vegetable processing wastes are global challenges but also suitable sources with a variety of nutrients for different fermentative products using bacteria, yeast or fungi. The interaction of microorganisms with bioactive compounds in fruit waste can have inhibitory or enhancing effect on microbial growth. In this study, the antimicrobial effect of 10 bioactive compounds, including octanol, ellagic acid, (−)-epicatechin, quercetin, betanin, ascorbic acid, limonene, hexanal, car-3-ene, and myrcene in the range of 0–240 mg/L on filamentous fungi Aspergillus oryzae and Aspergillus niger were investigated. These fungi were both found to be resistant to all compounds except octanol, which can be used as a natural antifungal agent, specifically against A. oryzae and A. niger contamination. On the contrary, polyphenols (quercetin and ellagic acid), ascorbic acid, and hexanal enhanced A. niger biomass yield 28%, 7.8%, 16%, and 6%, respectively. Furthermore, 240 mg/L car-3-ene was found to increase A. oryzae biomass yield 8%, while a 9% decrease was observed at lower concentration, 24 mg/L. Similarly, up to 17% decrease of biomass yield was observed from betanin and myrcene. The resistant nature of the fungi against FPW bioactive compounds shows the potential of these fungi for further application in waste valorization.

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