Cloud point extraction coupled with microwave-assisted back-extraction (CPE-MABE) for determination of Eszopiclone (Z-drug) using UV–Visible, HPLC and mass spectroscopic (MS) techniques: Spiked and in vivo analysis

2018 ◽  
Vol 1074-1075 ◽  
pp. 129-138 ◽  
Author(s):  
Shivpoojan Kori ◽  
Ankush Parmar ◽  
Jony Goyal ◽  
Shweta Sharma
Keyword(s):  
Cloud Point ◽  
Cloud Point Extraction ◽  
Back Extraction ◽  
Microwave Assisted ◽  
In Vivo Analysis ◽  
Uv Visible

Centrifugal microextraction tube-cloud point extraction coupled with gas chromatography for simultaneous determination of six phthalate esters in mineral water

2015 ◽  
Vol 7 (2) ◽  
pp. 560-565 ◽  
Author(s):  
Yun-Kai Lv ◽  
Wei Zhang ◽  
Meng-Meng Guo ◽  
Fang-Fang Zhao ◽  
Xiao-Xue Du
Keyword(s):  
Gas Chromatography ◽  
Simultaneous Determination ◽  
Cloud Point ◽  
Mineral Water ◽  
Cloud Point Extraction ◽  
Phthalate Esters ◽  
Back Extraction ◽  
Microwave Assisted

In this study, a centrifugal microextraction tube was first fabricated and used for CPE coupled microwave-assisted back-extraction of six phthalates from mineral water.

Determination of Pt from coke samples by ICP-MS after microwave assisted digestion and microwave assisted cloud point extraction

2009 ◽  
Vol 166 (3-4) ◽  
pp. 255-260 ◽  
Author(s):  
Matti Niemelä ◽  
Satu M. Huttunen ◽  
Stanislav S. Gornostayev ◽  
Paavo Perämäki
Keyword(s):  
Cloud Point ◽  
Cloud Point Extraction ◽  
Microwave Assisted ◽  
Icp Ms ◽  
Microwave Assisted Digestion

scholarly journals Preconcentration and determination of Metformine Hydrochloride in different samples by cloud point extraction coupling with uv-visible spectrophotometry

2016 ◽  
Vol 13 (2) ◽  
pp. 470-479
Author(s):  
Baghdad Science Journal
Keyword(s):  
Cloud Point ◽  
Calibration Curve ◽  
Cloud Point Extraction ◽  
Limit Of Detection ◽  
Molar Absorptivity ◽  
Basic Medium ◽  
Optimum Conditions ◽  
Visible Spectrophotometry ◽  
Uv Visible

This work was influenced the separation and preconcentration steps were carried out to determination of metformin (MET) in pharmaceutical preparations and human serum samples. Complex formation method and cloud-point extraction (CPE) coupling with UV-Visible spectrophotometry were used to investigated of study target.The results has showed the best optical characteristic for calibration curve and statistical data which were obtained under optimum conditions. The first method is based on the reaction of MET with nickel (II) in alkaline medium an absorption maximum ?)max) at 434nm. ''Beer's low'' is obeyed in the concentration range (10-100µg.ml-1) with molar absorptivity of 3.9x103 L.mol-1.cm-1.The limit of detection and quantitation values were 2.37 and7.11 µg.ml-1 respectively. The second method based on extraction of traces amounts of MET using the cloud-point extraction (CPE). This method implicated for using of a nonionic surfactant (Triton x-114) as an extraction medium which was entrap the hydrophobic complex formed between MET and nickel(ii) in basic medium as reaction system for designing the CPE procedure. The optimum conditions were similar the first method expect the amount of surfactant which was 0.5 ml. The concentrations range of calibration curve from 3.5to100 µg.ml-1 and molar absorptivity of 1.2x104 L.mol-1.cm-1. In this method was access to less of concentrations in Limit of detection and quantitation which were 0.74and 2.22 µg.ml-1 respectively. The precise (RSD %) and accuracy (recovery %) of both methods were ranged between 0.24-0.47, 97.86-98.68 respectively. The data of two methods were appeared high acceptable with standered of British Pharmacopoeia through using statistic methods (f-test and t-test), that they may be used in analysis of MET.

scholarly journals Cloud-Point Extraction Combined with Liquid Chromatography for the Determination of Ergosterol, a Natural Product with Diuretic Activity, in Rat Plasma, Urine, and Faeces

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Dan-Qian Chen ◽  
Jun-Min An ◽  
Ya-Long Feng ◽  
Ting Tian ◽  
Xiang-Yang Qin ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Cloud Point ◽  
Cloud Point Extraction ◽  
Rat Plasma ◽  
Ionic Surfactant ◽  
Pharmacokinetic Studies ◽  
Triton X

Ergosterol from many medicinal fungi has been demonstrated to possess a variety of pharmacological activitiesin vivoandin vitro. A new method based on cloud-point extraction has been developed, optimized and validated for the determination of ergosterol in rat plasma, urine and faeces by liquid chromatography. The non-ionic surfactant Triton X-114 was chosen as the extract solvent. The chromatographic separation was performed on an Inertsil ODS-3 analytical column with a mobile phase consisting of methanol and water (98 : 2, v/v) at a flow rate of 1 mL/min. The methodology was validated completely. The results indicated good performance in terms of specificity, linearity, detection and quantification limits, precision and accuracy. The method was successfully applied to the pharmacokinetic studies of ergosterol in rats. The results indicate that the ergosterol levels in feces are much higher than those in plasma and urine of the rat.

Sign in / Sign up

Export Citation Format

Share Document