pH-sensitive OEI-poly(aspartic acid- b -lysine) as charge shielding system for gene delivery

2015 ◽  
Vol 213 ◽  
pp. e104 ◽  
Author(s):  
Tianshi Feng ◽  
Huayu Tian ◽  
Xuan Dong ◽  
Michael Hon-Wah Lam ◽  
Haojun Liang ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Aspartic Acid ◽  
Ph Sensitive ◽  
Shielding System

Sulfathiazole grafted PEG-PLL as pH-sensitive shielding system for cationic gene delivery

2016 ◽  
Vol 73 (12) ◽  
pp. 3503-3511 ◽  
Author(s):  
Jialiang Xia ◽  
Jie Chen ◽  
Lin Lin ◽  
Zhaopei Guo ◽  
Bing Han ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ph Sensitive ◽  
Shielding System

scholarly journals Hepatocellular targeted α-tocopherol based pH sensitive galactosylated lipids: design, synthesis and transfection studies

MedChemComm ◽  
2018 ◽  
Vol 9 (2) ◽  
pp. 264-274 ◽  
Author(s):  
Venkanna Muripiti ◽  
Brijesh Lohchania ◽  
Srujan Kumar Marepally ◽  
Srilakshmi V. Patri
Keyword(s):  
Gene Delivery ◽  
Genetic Disorders ◽  
Ph Sensitive ◽  
Type I ◽  
Design Synthesis ◽  
Tyrosinemia Type I ◽  
Hereditary Tyrosinemia

Receptor mediated gene delivery to the liver offers advantages in treating genetic disorders such as hemophilia and hereditary tyrosinemia type I (HTI).

pH-sensitive N,N-(dimethyl)-N-alkanamine-N-oxides as gene delivery vectors

2017 ◽  
Vol 71 (9) ◽  
pp. 1739-1748 ◽  
Author(s):  
Gilda Liskayová ◽  
Lukáš Hubčík ◽  
Katarína Šišková ◽  
Ingrid Pauliková ◽  
Dominika Galliková ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ph Sensitive ◽  
Gene Delivery Vectors

Charge-conversional zwitterionic copolymer as pH-sensitive shielding system for effective tumor treatment

2015 ◽  
Vol 26 ◽  
pp. 45-53 ◽  
Author(s):  
Jie Chen ◽  
Xuan Dong ◽  
Tianshi Feng ◽  
Lin Lin ◽  
Zhaopei Guo ◽  
...  
Keyword(s):  
Ph Sensitive ◽  
Tumor Treatment ◽  
Shielding System

Preparation of pH-sensitive CaP nanoparticles coated with a phosphate-based block copolymer for efficient gene delivery

Polymer ◽  
2012 ◽  
Vol 53 (21) ◽  
pp. 4678-4685 ◽  
Author(s):  
Sangmok Jang ◽  
Seonju Lee ◽  
Heejin Kim ◽  
Jiyeon Ham ◽  
Ji-Hun Seo ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Gene Delivery ◽  
Ph Sensitive ◽  
Efficient Gene

Cyclen-based cationic lipids containing a pH-sensitive moiety as gene delivery vectors

2015 ◽  
Vol 13 (2) ◽  
pp. 620-630 ◽  
Author(s):  
Zheng Huang ◽  
Yan-Hong Liu ◽  
Yi-Mei Zhang ◽  
Ji Zhang ◽  
Qiang Liu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Structure Activity Relationship ◽  
Ph Sensitive ◽  
Cationic Lipids ◽  
Activity Relationship ◽  
Structure Activity ◽  
Gene Delivery Vectors

Imidazole-functionalized cationic lipids with a cyclen headgroup were synthesized, and the structure–activity relationship in gene delivery mediated by these lipids was discussed.

scholarly journals Anionic Lipid, pH-Sensitive Liposome-Gold Nanoparticle Hybrids for Gene Delivery - Quantitative Research of the Mechanism

Small ◽  
2015 ◽  
Vol 11 (29) ◽  
pp. 3511-3511 ◽  
Author(s):  
Baoji Du ◽  
Li Tian ◽  
Xiaoxiao Gu ◽  
Dan Li ◽  
Erkang Wang ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Gold Nanoparticle ◽  
Quantitative Research ◽  
Ph Sensitive ◽  
Anionic Lipid

Defined pH-sensitive nanogels as gene delivery platform for siRNA mediated in vitro gene silencing

2017 ◽  
Vol 5 (11) ◽  
pp. 2328-2336 ◽  
Author(s):  
Mathias Dimde ◽  
Falko Neumann ◽  
Felix Reisbeck ◽  
Svenja Ehrmann ◽  
Jose Luis Cuellar-Camacho ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Gene Silencing ◽  
Transfection Efficiency ◽  
Genetic Material ◽  
Ph Sensitive ◽  
Carrier System ◽  
High Transfection Efficiency ◽  
Delivery Platform ◽  
Low Cytotoxicity

An advanced cationic carrier system which combines high transfection efficiency with low cytotoxicity and a control over the release of the encapsulated genetic material by the reduction of the multivalent architecture upon pH triggered degradation was developed.

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