Circuit lifespan during continuous renal replacement therapy for combined liver and kidney failure

2012 ◽  
Vol 27 (6) ◽  
pp. 744.e7-744.e15 ◽  
Author(s):  
Horng-Ruey Chua ◽  
Ian Baldwin ◽  
Michael Bailey ◽  
Ashwin Subramaniam ◽  
Rinaldo Bellomo
2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Qi Zou ◽  
Cheng Liu ◽  
Gang Yu ◽  
Ximing Deng ◽  
Meiling Yu

One case of 54 years old female patient was admitted to hospital due to vomiting and diarrhea for 3 days and abnormal renal function for 1 day. The patient appeared repeatedly vomiting and watery stools 6 hours after eating 2 grain of raw carp fish bile and gradually appeared oliguresis, whole body skin yellow dye and fever symptoms. The condition of patient had no improvement after visiting the emergency department of local county hospital. She was checked in department of nephropathy in our hospital for further diagnosis and treatment. Because the patient's condition was serious and the function of liver and kidney was damaged, diagnosed as severe multiple organ dysfunction syndrome (MODS), she was transferred to ICU rescue to protect the liver, maintain water and electrolyte balance, control blood sugar, improve the circulation and give other drug treatments and actively carry out bedside continuous renal replacement therapy. Then the body temperature and hemogram of the patients became normal, liver and kidney function improved obviously, urinary production became normal, skin yellow dye faded and vital signs became stable. The successful treatment of this patient indicated that bedside continuous renal replacement therapy can not only have a good support for the kidneys but also reduce the waterfall effect of inflammatory of patients with severe MODS, which has great therapeutic effect on the multi organ dysfunction caused by fish bile poisoning.


2021 ◽  
Vol 9 (2) ◽  
pp. 159-162
Author(s):  
Younes Oujidi ◽  
Imane Melhaoui ◽  
Layla Kherroubi ◽  
Houssam Bkiyar ◽  
Brahim Housni

Introduction: Extracorporeal membrane oxygenation (ECMO) is a therapy that ameliorate the oxygenation of hypoxemia refractory patient it could be associated to a kidney failure that necessity a Continuous Renal Replacement Therapy. Case Report: We report the case of a 68-year-old patient, who presents ARDS due to covid infection, during his hospitalisation the patient presented a refractory hypoxemia with the need to set up ECMO, the case worsened with kidney failure with need for CRRT. Conclusion: The association between ECMO and CRRT might be a safe and effective technique. A variety of ECMO and CRRT combination methods can be chosen, this remains an association that should be investigated in order to improve the prognosis of kidney failure on ECMO.


2020 ◽  
Author(s):  
Peter Okholm ◽  
Jan Kampmann

Abstract Background: Coronavirus disease 2019 also known as COVID-19 has been recognized by WHO as a global pandemic and has spread to most of the world. The disease has a multitude of clinical presentations, and especially the development of acute kidney injury has been associated with increased mortality.Case Presentation: A 71-year old Caucasian male was admitted with fever and dyspnea to the emergency department. His medical history included type 2 diabetes and hypertension. Blood tests showed a normal kidney function before admission with a creatinine of 0,8 mg/dL. Clinical examination, blood tests and Chest X-ray suggested COVID-19. At admission the diagnose COVID-19 was confirmed, fluid therapy was commenced and Angiotensin-converting enzyme therapy discontinued. The patients was intubated due to respiratory failures and transferred to the intensive care ward where he developed acute anuric kidney failure and was started in continuous renal replacement therapy. After 6 days of dialysis treatment his kidney function slowly started to improve, and he was discharged after 26 days of admission. 42 days after admission his creatinine was measured to 1.3 mg/dLConclusion: We present the rare case of a Caucasian male, who not only survived COVID-19 induced kidney failure that required continuous renal replacement therapy, but returned to almost baseline creatinine. We discuss the role of Angiotensin-converting enzyme inhibitor treatment in COVID-19 and the potential pathophysiological mechanism surrounding AKI in COVID-19 patients in literature, and connect it to our case report.


2018 ◽  
Vol 8 (2) ◽  
pp. 130-137
Author(s):  
Vedran Premužić ◽  
Marija Santini ◽  
Mario Laganović ◽  
Marijana Ćorić ◽  
Bojan Jelaković

Background: Varicella zoster virus (VZV) is distributed worldwide and is highly contagious. In adults and immunosuppressed patients of any age, the clinical course is much more severe. The most severe complications are pneumonia (the main cause of lethal outcomes in this infection), encephalitis, and very rarely Reye syndrome and hepatitis. Case Presentation: We present a 59-year-old man who came to the emergency department due to varicella and diarrhea. During initial evaluation acute kidney failure (AKF) was diagnosed, and the patient was admitted to the intensive care unit. Continuous renal replacement therapy was applied, and the patient was treated with acyclovir in adjusted doses; renal biopsy revealed acute tubular necrosis. Complete renal function recovery was established after 12 days. Conclusion: VZV infection occurs in a range of clinical scenarios, sometimes presenting only with mild symptoms, but in some other setting it can result in severe AKF even in healthy kidneys. Acute VZV infection can lead to isolated, clinically significant kidney failure. The administration of continuous renal replacement therapy and adjusted doses of acyclovir has a favorable effect on the course of the infection, with complete recovery of kidney function.


2015 ◽  
Vol 41 (4) ◽  
pp. 254-263 ◽  
Author(s):  
Ling Zhang ◽  
Aiko Tanaka ◽  
Guijun Zhu ◽  
Ian Baldwin ◽  
Glenn M. Eastwood ◽  
...  

Background: We aimed to describe the previously unstudied relationship between circuit pressures and circuit clotting, here labeled as ‘artificial kidney failure' (AKF), in patients receiving continuous renal replacement therapy (CRRT). Methods: We performed an observational study of CRRT-treated critically ill patients to continuously record the multiple CRRT circuit pressures. Results: Three patterns of access outflow dysfunction (AOD) were also noted: severe, moderate and mild. Compared with circuits without AOD, circuits experiencing at least one AOD episode had shorter lifespans (14.2 ± 12.7 vs. 21.3 ± 16.5 h, p = 0.057). This effect was more obvious with moderate or severe AOD (8.7 ± 4.6 vs. 20.6 ± 15.7 h, p = 0.007). If any AOD events occurred within the first 4 h, the sensitivity and specificity in predicting early-immediate AKF were 53.4 and 94.4%, respectively. Conclusions: Early and intermediate AKF during CRRT is most likely dependent on AOD, which is a frequent event with variable severity.


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