A return to normal kidney function in a Caucasian male after COVID-19 induced dialysis-requiring kidney failure

Angiotensin Converting Enzyme ◽

Replacement Therapy ◽

Kidney Function ◽

Kidney Failure ◽

Converting Enzyme ◽

Normal Kidney ◽

Caucasian Male ◽

Blood Tests

Abstract Background: Coronavirus disease 2019 also known as COVID-19 has been recognized by WHO as a global pandemic and has spread to most of the world. The disease has a multitude of clinical presentations, and especially the development of acute kidney injury has been associated with increased mortality.Case Presentation: A 71-year old Caucasian male was admitted with fever and dyspnea to the emergency department. His medical history included type 2 diabetes and hypertension. Blood tests showed a normal kidney function before admission with a creatinine of 0,8 mg/dL. Clinical examination, blood tests and Chest X-ray suggested COVID-19. At admission the diagnose COVID-19 was confirmed, fluid therapy was commenced and Angiotensin-converting enzyme therapy discontinued. The patients was intubated due to respiratory failures and transferred to the intensive care ward where he developed acute anuric kidney failure and was started in continuous renal replacement therapy. After 6 days of dialysis treatment his kidney function slowly started to improve, and he was discharged after 26 days of admission. 42 days after admission his creatinine was measured to 1.3 mg/dLConclusion: We present the rare case of a Caucasian male, who not only survived COVID-19 induced kidney failure that required continuous renal replacement therapy, but returned to almost baseline creatinine. We discuss the role of Angiotensin-converting enzyme inhibitor treatment in COVID-19 and the potential pathophysiological mechanism surrounding AKI in COVID-19 patients in literature, and connect it to our case report.

Circuit lifespan during continuous renal replacement therapy for combined liver and kidney failure

Journal of Critical Care ◽

10.1016/j.jcrc.2012.08.016 ◽

2012 ◽

Vol 27 (6) ◽

pp. 744.e7-744.e15 ◽

Cited By ~ 12

Author(s):

Horng-Ruey Chua ◽

Ian Baldwin ◽

Michael Bailey ◽

Ashwin Subramaniam ◽

Rinaldo Bellomo

Keyword(s):

Replacement Therapy ◽

Kidney Failure ◽

Liver And Kidney

Kidney Replacement Therapy in COVID-19 Induced Kidney Failure and Septic Shock: A Pediatric Continuous Renal Replacement Therapy [PCRRT] Position on Emergency Preparedness With Resource Allocation

Frontiers in Pediatrics ◽

10.3389/fped.2020.00413 ◽

2020 ◽

Vol 8 ◽

Cited By ~ 1

Author(s):

Rupesh Raina ◽

Ronith Chakraborty ◽

Sidharth Kumar Sethi ◽

Timothy Bunchman

Keyword(s):

Septic Shock ◽

Resource Allocation ◽

Replacement Therapy ◽

Kidney Failure ◽

Emergency Preparedness ◽

Kidney Replacement Therapy

Continuous Renal Replacement Therapy: A Review

Journal of Anesthesiology and Clinical Research ◽

10.37275/jacr.v1i2.138 ◽

2021 ◽

Vol 1 (2) ◽

pp. 63-77

Author(s):

Mujahidin ◽

Yasir Teuku ◽

Dzaky. A. N

Keyword(s):

Acute Kidney Injury ◽

Renal Function ◽

Replacement Therapy ◽

Organ Failure ◽

Kidney Function ◽

Human Body ◽

Kidney Injury ◽

Hemodynamic Stability

Kidney is an important organ to maintain hemodynamic stability inside the human body. In patient with acute kidney injury (AKI) there was a decreased kidney function that could interfere hemodynamic stability which can lead to multi organ failure even death. Around 5-10% patients with AKI required renal replacement therapy (RRT) to support their decreased renal function. Continuous renal replacement therapy (CRRT) is one of RRT modality that commonly used for patients with AKI who are hemodynamically unstable or in critically ill conditions.CRRT could divided into 4 mode, slow continuous ultrafiltration (SCUF), continuous veno-venous hemofiltration (CVVH), continuous veno-venous hemodialysis (CVVHD) and continuous veno-venous hemodialfiltration (CVVHDF). CRRT used based on renal and nonrenal indication. Several studies are still trying to prove nonrenal indication of RRT, to ascertain whether CRRT could be used as therapy effectively. Therefore the indication, the mechanism and the comparison of renal replacement therapy are very important to be understood.

Continuous renal replacement therapy and ECMO in COVID patients, a Moroccan case report experience

World Journal of Advanced Research and Reviews ◽

10.30574/wjarr.2021.9.2.0059 ◽

2021 ◽

Vol 9 (2) ◽

pp. 159-162

Author(s):

Younes Oujidi ◽

Imane Melhaoui ◽

Layla Kherroubi ◽

Houssam Bkiyar ◽

Brahim Housni

Keyword(s):

Case Report ◽

Extracorporeal Membrane Oxygenation ◽

Replacement Therapy ◽

Kidney Failure ◽

Effective Technique ◽

Combination Methods ◽

Refractory Hypoxemia ◽

Set Up

Introduction: Extracorporeal membrane oxygenation (ECMO) is a therapy that ameliorate the oxygenation of hypoxemia refractory patient it could be associated to a kidney failure that necessity a Continuous Renal Replacement Therapy. Case Report: We report the case of a 68-year-old patient, who presents ARDS due to covid infection, during his hospitalisation the patient presented a refractory hypoxemia with the need to set up ECMO, the case worsened with kidney failure with need for CRRT. Conclusion: The association between ECMO and CRRT might be a safe and effective technique. A variety of ECMO and CRRT combination methods can be chosen, this remains an association that should be investigated in order to improve the prognosis of kidney failure on ECMO.

Continuous Renal Replacement Therapy: A Review

Journal of Anesthesiology and Clinical Research ◽

10.37275/jacr.v1i2.212 ◽

2020 ◽

Vol 1 (2) ◽

pp. 63-77

Author(s):

Muja Hidin ◽

Yasir Teuku ◽

Dzaky.A.N

Keyword(s):

Acute Kidney Injury ◽

Renal Function ◽

Replacement Therapy ◽

Organ Failure ◽

Kidney Function ◽

Human Body ◽

Kidney Injury ◽

Hemodynamic Stability

ABSTRACT Kidney is an important organ to maintain hemodynamic stability inside the human body. In patient with acute kidney injury (AKI) there was a decreased kidney function that could interfere hemodynamic stability which can lead to multi organ failure even death. Around 5-10% patients with AKI required renal replacement therapy (RRT) to support their decreased renal function. Continuous renal replacement therapy (CRRT) is one of RRT modality that commonly used for patients with AKI who are hemodynamically unstable or in critically ill conditions. CRRT could divided into 4 mode, slow continuous ultrafiltration (SCUF), continuous veno-venous hemofiltration (CVVH), continuous veno-venous hemodialysis (CVVHD) and continuous veno-venous hemodialfiltration (CVVHDF). CRRT used based on renal and nonrenal indication. Several studies are still trying to prove nonrenal indication of RRT, to ascertain whether CRRT could be used as therapy effectively. Therefore the indication, the mechanism and the comparison of renal replacement therapy are very important to be understood.

Baclofen self-poisoning: Is renal replacement therapy efficient in patient with normal kidney function?

Anaesthesia Critical Care & Pain Medicine ◽

10.1016/j.accpm.2020.07.021 ◽

2020 ◽

Vol 39 (6) ◽

pp. 813-817

Author(s):

Marion Brunet ◽

Maxime Léger ◽

Pierre-André Billat ◽

Bénédicte Lelièvre ◽

Nicolas Lerolle ◽

...

Keyword(s):

Replacement Therapy ◽

Kidney Function ◽

Normal Kidney ◽

Normal Kidney Function

Acute Kidney Failure as a Single Complication of Varicella Virus Infection in an Adult Patient

Case Reports in Nephrology and Dialysis ◽

10.1159/000491627 ◽

2018 ◽

Vol 8 (2) ◽

pp. 130-137

Author(s):

Vedran Premužić ◽

Marija Santini ◽

Mario Laganović ◽

Marijana Ćorić ◽

Bojan Jelaković

Keyword(s):

Replacement Therapy ◽

Kidney Failure ◽

Complete Recovery ◽

Acute Kidney Failure ◽

Favorable Effect ◽

Reye Syndrome ◽

Varicella Zoster ◽

Clinical Scenarios

Background: Varicella zoster virus (VZV) is distributed worldwide and is highly contagious. In adults and immunosuppressed patients of any age, the clinical course is much more severe. The most severe complications are pneumonia (the main cause of lethal outcomes in this infection), encephalitis, and very rarely Reye syndrome and hepatitis. Case Presentation: We present a 59-year-old man who came to the emergency department due to varicella and diarrhea. During initial evaluation acute kidney failure (AKF) was diagnosed, and the patient was admitted to the intensive care unit. Continuous renal replacement therapy was applied, and the patient was treated with acyclovir in adjusted doses; renal biopsy revealed acute tubular necrosis. Complete renal function recovery was established after 12 days. Conclusion: VZV infection occurs in a range of clinical scenarios, sometimes presenting only with mild symptoms, but in some other setting it can result in severe AKF even in healthy kidneys. Acute VZV infection can lead to isolated, clinically significant kidney failure. The administration of continuous renal replacement therapy and adjusted doses of acyclovir has a favorable effect on the course of the infection, with complete recovery of kidney function.

Patterns and Mechanisms of Artificial Kidney Failure during Continuous Renal Replacement Therapy

Blood Purification ◽

10.1159/000441968 ◽

2015 ◽

Vol 41 (4) ◽

pp. 254-263 ◽

Cited By ~ 5

Author(s):

Ling Zhang ◽

Aiko Tanaka ◽

Guijun Zhu ◽

Ian Baldwin ◽

Glenn M. Eastwood ◽

...

Keyword(s):

Observational Study ◽

Replacement Therapy ◽

Critically Ill ◽

Sensitivity And Specificity ◽

Kidney Failure ◽

Critically Ill Patients ◽

Artificial Kidney ◽

Frequent Event

Background: We aimed to describe the previously unstudied relationship between circuit pressures and circuit clotting, here labeled as ‘artificial kidney failure' (AKF), in patients receiving continuous renal replacement therapy (CRRT). Methods: We performed an observational study of CRRT-treated critically ill patients to continuously record the multiple CRRT circuit pressures. Results: Three patterns of access outflow dysfunction (AOD) were also noted: severe, moderate and mild. Compared with circuits without AOD, circuits experiencing at least one AOD episode had shorter lifespans (14.2 ± 12.7 vs. 21.3 ± 16.5 h, p = 0.057). This effect was more obvious with moderate or severe AOD (8.7 ± 4.6 vs. 20.6 ± 15.7 h, p = 0.007). If any AOD events occurred within the first 4 h, the sensitivity and specificity in predicting early-immediate AKF were 53.4 and 94.4%, respectively. Conclusions: Early and intermediate AKF during CRRT is most likely dependent on AOD, which is a frequent event with variable severity.