scholarly journals Integrated infection control strategy to minimize nosocomial infection of coronavirus disease 2019 among ENT healthcare workers

2020 ◽  
Vol 104 (4) ◽  
pp. 454-455 ◽  
Author(s):  
D. Lu ◽  
H. Wang ◽  
R. Yu ◽  
H. Yang ◽  
Y. Zhao
Keyword(s):  
Nosocomial Infection ◽  
Infection Control ◽  
Control Strategy ◽  
Healthcare Workers

scholarly journals Evaluation of a home-based 7-day infection control strategy for healthcare workers following high-risk exposure to severe acute respiratory coronavirus virus 2 (SARS-CoV-2): A cohort study

2020 ◽  
pp. 1-4
Author(s):  
Carla Benea ◽  
Laura Rendon ◽  
Jesse Papenburg ◽  
Charles Frenette ◽  
Ahmed Imacoudene ◽  
...  
Keyword(s):  
High Risk ◽  
Infection Control ◽  
Control Strategy ◽  
Healthcare Workers ◽  
Control Strategies ◽  
Risk Exposure ◽  
Nasopharyngeal Swab ◽  
Home Based ◽  
Respiratory Coronavirus ◽  
Second Wave

Abstract Objective: Evidence-based infection control strategies are needed for healthcare workers (HCWs) following high-risk exposure to severe acute respiratory coronavirus virus 2 (SARS-CoV-2). In this study, we evaluated the negative predictive value (NPV) of a home-based 7-day infection control strategy. Methods: HCWs advised by their infection control or occupational health officer to self-isolate due to a high-risk SARS-CoV-2 exposure were enrolled between May and October 2020. The strategy consisted of symptom-triggered nasopharyngeal SARS-CoV-2 RNA testing from day 0 to day 7 after exposure and standardized home-based nasopharyngeal swab and saliva testing on day 7. The NPV of this strategy was calculated for (1) clinical coronavirus disease 2019 (COVID-19) diagnosis from day 8–14 after exposure, and for (2) asymptomatic SARS-CoV-2 detected by standardized nasopharyngeal swab and saliva specimens collected at days 9, 10, and 14 after exposure. Interim results are reported in the context of a second wave threatening this essential workforce. Results: Among 30 HCWs enrolled, the mean age was 31 years (SD, ±9), and 24 (80%) were female. Moreover, 3 were diagnosed with COVID-19 by day 14 after exposure (secondary attack rate, 10.0%), and all cases were detected using the 7-day infection control strategy: the NPV for subsequent clinical COVID-19 or asymptomatic SARS-CoV-2 detection by day 14 was 100.0% (95% CI, 93.1%–100.0%). Conclusions: Among HCWs with high-risk exposure to SARS-CoV-2, a home-based 7-day infection control strategy may have a high NPV for subsequent COVID-19 and asymptomatic SARS-CoV-2 detection. Ongoing data collection and data sharing are needed to improve the precision of the estimated NPV, and here we report interim results to inform infection control strategies in light of a second wave threatening this essential workforce.

scholarly journals Evaluation of a home-based 7-day infection control strategy for healthcare workers following high-risk exposure to SARS-CoV-2: a cohort study

2020 ◽  
Author(s):  
Carla Benea ◽  
Laura Rendon ◽  
Jesse Papenburg ◽  
Charles Frenette ◽  
Ahmed Imcaoudene ◽  
...  
Keyword(s):  
High Risk ◽  
Infection Control ◽  
Control Strategy ◽  
Healthcare Workers ◽  
Control Strategies ◽  
Risk Exposure ◽  
Nasopharyngeal Swab ◽  
Post Exposure ◽  
Home Based ◽  
Second Wave

ABSTRACTBackgroundEvidence-based infection control strategies are needed for healthcare workers (HCWs) following high-risk exposure to SARS-CoV-2. This study evaluated the negative predictive value (NPV) of a home-based 7-day infection control strategy.MethodsHCWs advised by their Infection Control or Occupational Health officer to self-isolate due to a high-risk SARS-CoV-2 exposure were enrolled between May-September 2020. The strategy consisted of symptom-triggered nasopharyngeal SARS-CoV-2 RNA testing from day 0-6 post exposure, followed by standardized home-based nasopharyngeal swab and saliva testing on day 7. The NPV of this strategy was calculated for i) clinical COVID-19 diagnosis from day 8-14 post exposure, and for ii) asymptomatic SARS-CoV-2 detected by standardized nasopharyngeal swab and saliva specimens collected at days 9-10 and 14 post exposure. Interim results are reported in the context of a second wave threatening this essential workforce.ResultsAmong 30 HCWs enrolled to date (age 31±9 years, 24 [80.0%] female), 3 were diagnosed with COVID-19 by day 14 post exposure (secondary attack rate 10.0%), with all cases detected by the 7-day infection control strategy: NPV for subsequent clinical COVID-19 or asymptomatic SARS-CoV-2 detection by day 14 was 100.0% (95%CI: 93.1-100.0%).InterpretationAmong HCWs with high-risk exposure to SARS-CoV-2, a home-based 7-day infection control strategy may have a high NPV for subsequent COVID-19 and asymptomatic SARS-CoV-2 detection. While ongoing data collection and data sharing are needed to improve the precision of the estimated NPV, we report interim results to inform infection control strategies in light of a second wave threatening this essential workforce.

scholarly journals An Integrated Strategy for the Prevention of SARS-CoV-2 Infection in Healthcare Workers: A Prospective Observational Study

2020 ◽  
Vol 17 (16) ◽  
pp. 5785 ◽  
Author(s):  
Anna Maria Cattelan ◽  
Lolita Sasset ◽  
Eugenia Di Meco ◽  
Silvia Cocchio ◽  
Francesco Barbaro ◽  
...  
Keyword(s):  
Observational Study ◽  
Infection Control ◽  
Control Strategy ◽  
Healthcare Workers ◽  
Prospective Observational Study ◽  
Secondary Endpoint ◽  
University Hospital ◽  
Healthcare Personnel ◽  
North East ◽  
Hospital Infection Control

Background: Since the beginning of SARS-CoV-2 outbreak, a large number of infections have been reported among healthcare workers (HCWs). The aim of this study was to investigate the occurrence of SARS-CoV-2 infection among HCWs involved in the first management of infected patients and to describe the measures adopted to prevent the transmission in the hospital. Methods: This prospective observational study was conducted between February 21 and April 16, 2020, in the Padua University Hospital (north-east Italy). The infection control policy adopted consisted of the following: the creation of the “Advanced Triage” area for the evaluation of SARS-CoV-2 cases, and the implementation of an integrated infection control surveillance system directed to all the healthcare personnel involved in the Advance Triage area. HCWs were regularly tested with nasopharyngeal swabs for SARS-CoV-2; body temperature and suggestive symptoms were evaluated at each duty. Demographic and clinical data of both patients and HCWs were collected and analyzed; HCWs’ personal protective equipment (PPE) consumption was also recorded. The efficiency of the control strategy among HCWs was evaluated identifying symptomatic infection (primary endpoint) and asymptomatic infection (secondary endpoint) with confirmed detection of SARS-CoV-2. Results: 7595 patients were evaluated in the Advanced Triage area: 5.2% resulted positive and 72.4% was symptomatic. The HCW team was composed of 60 members. A total of 361 nasopharyngeal swabs were performed on HCWs. All the swabs resulted negative and none of the HCWs reached the primary or the secondary endpoint. Conclusions: An integrated hospital infection control strategy, consisting of dedicated areas for infected patients, strict measures for PPE use and mass surveillance, is successful to prevent infection among HCWs.

scholarly journals Multi-pronged infection control strategy to achieve zero nosocomial COVID-19 infection among Hong Kong healthcare workers in the first 300 days of combat

2021 ◽  
pp. 1-39
Author(s):  
Vincent Chi-Chung Cheng ◽  
Shuk-Ching Wong ◽  
Danny Wah-Kun Tong ◽  
Vivien Wai-Man Chuang ◽  
Jonathan Hon-Kwan Chen ◽  
...  
Keyword(s):  
Hong Kong ◽  
Infection Control ◽  
Control Strategy ◽  
Healthcare Service ◽  
Healthcare Workers ◽  
Professional Staff ◽  
Public Healthcare ◽  
Clinical Settings ◽  
Third Wave ◽  
Median Length

Abstract Background: Nosocomial outbreaks leading to healthcare workers (HCWs) infection and death have been increasingly reported during the coronavirus disease 2019 (COVID-19) pandemic. An effective intervention is urgently needed to reduce nosocomial acquisition. Methods: We summarized our experience of multi-pronged infection control (IC) strategy in the first 300 days (December 31, 2019 to October 25, 2020) of COVID-19 era under the governance of Hospital Authority in Hong Kong. Results: Of 5,296 COVID-19 patients, 4,808 (90.8%) were diagnosed in the first (142 cases), second (896 cases), and third wave (3,770 cases) of COVID-19 in Hong Kong. Except for one patient who died before admission, all COVID-19 patients were admitted to public healthcare system which culminated to 78,834 COVID-19 patient-days. The median length of stay was 13 days (ranged, 1-128). Of 81,955 HCWs, thirty-eight (0.05%) HCWs [13 professional (2 doctors, 11 nurses) and 25 non-professional staff], had COVID-19. Except for 5 of 38 (13.2%) infected by HCW-to-HCW transmission in the non-clinical settings, no HCW had documented transmission from COVID-19 patients in the hospitals. The incidence of COVID-19 among HCWs was significantly lower than that of our general population (0.46 per 1,000 HCWs vs 0.71 per 1,000 population, p=0.008). The incidence of COVID-19 among professional staff was significantly lower than that of non-professional staff (0.30 vs 0.66 per 1,000 FTE, p=0.022). Conclusion: Hospital-based approach spared our healthcare service from being overloaded. No nosocomial COVID-19 in HCWs was found in the first 300 days of COVID-19 era in Hong Kong with our multi-pronged IC strategy.

Knowledge of COVID-19 infection control among healthcare workers in radiology departments in Saudi Arabia

2020 ◽  
pp. 1-10
Author(s):  
Rowa Aljondi ◽  
Salem Saeed Alghamdi ◽  
Ikhlas Abdelaziz ◽  
Lubna Bushara ◽  
Somayah Alghamdi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Infection Control ◽  
Healthcare Workers

scholarly journals An analysis of infection control of varicella-zoster virus infections in Addenbrooke's Hospital Cambridge over a 5-year period, 1987–92

1996 ◽  
Vol 117 (1) ◽  
pp. 165-171 ◽  
Author(s):  
T. G. Wreghitt ◽  
J. Whipp ◽  
C. Redpath ◽  
W. Hollingworth
Keyword(s):  
Nosocomial Infection ◽  
Infection Control ◽  
Prospective Study ◽  
Varicella Zoster Virus ◽  
Virus Infections ◽  
Patient Case ◽  
Varicella Zoster ◽  
Staff Members ◽  
Spread Of Infection ◽  
The Cost

SummaryThis prospective study analyses infections with varicella-zoster virus (VZV) in Addenbrooke's Hospital, Cambridge during 1987–92 and examines the spread of infection. In total, 93 patients and staff experienced VZV infection. Twenty-one patients had varicella and 49 experienced zoster. None of 101 patients and 1 of 625 staff members in contact with varicella cases acquired infection. By contrast, 2 of 227 patients, and 5 of 1039 staff in contact with zoster cases acquired varicella. One out of 28 (3·6%) VZV antibody-negative patients and staff in contact with varicella acquired infection, compared with 5 out of 29 (17·2%) VZV antibody-negative patients and staff in contact with zoster. Thus, zoster was found to be a more frequent cause of nosocomial infection than varicella. Fourteen members of staff had VZV infection during the study period. One of 99 patients and none of 389 staff members in contact with these cases developed varicella. The cost of dealing with infection control for VZV infections in our hospital is estimated to be £714 per patient case and a total of £13204 per year.

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