Obstetric Outcome of Infertile Women Following IVF-ET after Hysteroscopic Surgical Correction of Incomplete Uterine Septum or Arcuate Uterus

Rates of caesarean section have increased over recent years and so too have associated complications, one of which is a caesarean scar defect (CSD). The defect may cause gynaecological symptoms, such as menometrorrhagia, infertility, chronic abdominal/pelvic pain or it may be asymptomatic. The presence of CSD may lead to obstetrical sequalae such as preterm delivery, uterine rupture, caesarean scar pregnancy or abnormal placenta implantation. Three cases of CSD are described here. In one case, surgical correction of the CSD was performed before a subsequent pregnancy with an uncomplicated obstetric outcome. In the other two cases, surgical correction of the CSD was not performed and the pregnancies were complicated by caesarean scar dehiscence and caesarean scar pregnancy. We suggest that women with a CSD may benefit from surgical correction of the defect before becoming pregnant to reduce the likelihood of serious complications.

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Serum Matrix Metalloproteinase and Tissue Inhibitor of Metalloproteinase Concentrations in Infertile Women Achieved Pregnancy Following IVF-ET

American Journal of Reproductive Immunology ◽

10.1111/j.1600-0897.2005.00297.x ◽

2005 ◽

Vol 54 (4) ◽

pp. 186-192 ◽

Cited By ~ 10

Author(s):

Hiroaki Shibahara ◽

Tatsuya Suzuki ◽

Kumiko Kikuchi ◽

Yuki Hirano ◽

Mitsuaki Suzuki

Keyword(s):

Matrix Metalloproteinase ◽

Tissue Inhibitor Of Metalloproteinase ◽

Tissue Inhibitor ◽

Infertile Women ◽

Ivf Et

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Inositol supplement improves clinical pregnancy rate in infertile women undergoing ovulation induction for ICSI or IVF-ET

Medicine ◽

10.1097/md.0000000000008842 ◽

2017 ◽

Vol 96 (49) ◽

pp. e8842 ◽

Cited By ~ 14

Author(s):

Xiangqin Zheng ◽

Danmei Lin ◽

Yulong Zhang ◽

Yuan Lin ◽

Jianrong Song ◽

...

Keyword(s):

Pregnancy Rate ◽

Ovulation Induction ◽

Clinical Pregnancy ◽

Clinical Pregnancy Rate ◽

Infertile Women ◽

Ivf Et

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Effects of Sperm Immobilizing Antibodies on Pregnancy Outcome in Infertile Women Treated With IVF-ET

American Journal of Reproductive Immunology ◽

10.1111/j.1600-0897.1996.tb00146.x ◽

1996 ◽

Vol 36 (2) ◽

pp. 96-100 ◽

Cited By ~ 19

Author(s):

Hiroaki Shibahara ◽

Mizumi Mitsuo ◽

Yoshikazu Ikeda ◽

Minoru Shigeta ◽

Koji Koyama

Keyword(s):

Pregnancy Outcome ◽

Infertile Women ◽

Ivf Et

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Coping Strategies Mediate the Association Between Stigma and Fertility Quality of Life in Infertile Women Undergoing in Vitro Fertilization-Embryo Transfer.

10.21203/rs.3.rs-198191/v2 ◽

2021 ◽

Author(s):

Xiaoyu JING ◽

Wei GU ◽

Lu ZHANG ◽

Runna MIAO ◽

Xiuli XU ◽

...

Keyword(s):

Quality Of Life ◽

In Vitro Fertilization ◽

Coping Strategies ◽

Embryo Transfer ◽

Indirect Effect ◽

Vitro Fertilization ◽

Infertile Women ◽

Ivf Et

Abstract Background The mediating role of coping strategies and its relationship with psychological well-being and quality of life has been considered in the literature. However, there is little research to explore the mechanism of coping strategies on stigma and fertility quality of life (FertiQoL) in infertile women undergoing In Vitro Fertilization Embryo Transfer (IVF-ET). The aim of this study was to examine the mediating effect of coping strategies on the relationship between stigma and fertility quality of life (FertiQoL) in Chinese infertile women undergoing In Vitro Fertilization Embryo Transfer (IVF-ET).Methods: In this cross-sectional study, a total of 768 infertile women undergoing IVF-ET were recruited from Assisted Reproductive Center of Shaanxi Province, China. The personal information, infertility stigma scale, coping strategy scale and FertiQoL scale were measured using a set of questionnaires. The multiple mediator model was performed using AMOS 21.0.Results: The model showed a significant negative direct effect between stigma on FertiQoL (direct effect= -2.375, BC 95% CI= -2.764, -1.987). There were significantly negative indirect effects of stigma on FertiQoL through active-avoidance (indirect effect = -0.706; BC 95% CI = -0.950, -0.497), active-confronting (indirect effect = -0.267; BC 95% CI= -0.414, -0.136) and passive-avoidance (indirect effect= -0.244; BC 95% CI = -0.368, -0.142), respectively. The meaning-based coping played a positive intermediary role (indirect effect=0.105; BC 95% CI = 0.046, 0.190). The model explained 69.4% of the variance in FertiQoL.Conclusion: Active-avoidance coping strategy is the most important mediator factor between stigma and FertiQoL in infertile women undergoing IVF-ET treatment. Meaning-based coping strategy plays a positive mediating role between stigma and FertiQoL.

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Impact of Positive Interferon-Gamma Release Assay on IVF-ET Pregnancy Outcomes in Infertile Patients With Untreated Prior Tuberculosis: A Prospective Cohort Study

Frontiers in Medicine ◽

10.3389/fmed.2021.749410 ◽

2021 ◽

Vol 8 ◽

Author(s):

Xiaoyan Gai ◽

Hongbin Chi ◽

Lin Zeng ◽

Wenli Cao ◽

Lixue Chen ◽

...

Keyword(s):

Cohort Study ◽

Interferon Gamma ◽

Pregnancy Outcomes ◽

Prospective Cohort ◽

Interferon Gamma Release Assay ◽

Infertile Women ◽

Tb Treatment ◽

Release Assay ◽

Infertile Patients ◽

Ivf Et

Introduction: Tuberculosis (TB) is a major infectious disease that seriously endangers human health and female reproduction. In our previous study, 10.4% of infertile patients preparing for In vitro fertilization and embryo transfer (IVF-ET) had prior pulmonary TB (PTB) as detected on chest X-ray (CXR) screening. Among them, 81.8% did not receive anti-TB treatment. It remains unclear whether infertile women with untreated prior PTB have latent TB infection (LTBI) and whether LTBI affects IVF-ET outcomes. In this study, we aim to analyze the relationship between LTBI and pregnancy outcomes following IVF-ET in patients with untreated prior PTB.Methods and Analysis: We designed a prospective cohort study of 1,200 infertile women with CXR findings suggestive of old-healed untreated TB, who are preparing for IVF-ET. Patients with a history of active TB and anti-TB treatment will be excluded. Interferon-gamma release assay (IGRA) will be used in patients with CXR findings suggestive of old-healed untreated TB to construct a cohort of IGRA-positive and IGRA-negative patients. Participants will undergo IVF-ET. General information, including age, body mass index, infertility causes, and controlled ovarian hyperstimulation protocol, will be recorded. Participants will be followed up during pregnancy. The primary outcome is live birth. Secondary outcomes include the numbers of retrieved oocytes, high-quality embryo rate, clinical pregnancy, number of active TB cases during pregnancy, and miscarriage.Ethics and Dissemination: The study was approved by the Ethics Committee of Peking University Third Hospital [approval number (2020)218-01; approval date: June 19, 2020]. The research results will be disseminated through scientific/medical conferences and published in academic journals.Trial Registration:ClinicalTrials.gov; identifier: NCT04443283.

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Analysis of the levels of hope and influencing factors in infertile women with first-time and repeated IVF-ET cycles

Reproductive Health ◽

10.1186/s12978-021-01248-y ◽

2021 ◽

Vol 18 (1) ◽

Author(s):

Ying Ni ◽

Limin Huang ◽

Chenye Tong ◽

Wen Qian ◽

Qiong Fang

Keyword(s):

Social Support ◽

Linear Regression ◽

Influencing Factors ◽

Repeated Cycle ◽

Infertile Women ◽

Time Cycle ◽

Cycle Group ◽

Adjustment Test ◽

First Time ◽

Ivf Et

Abstract Purpose To explore the hope levels and influencing factors in infertile women undergoing first-time and repeated in vitro fertilization-embryo transfer (IVF-ET) cycles. Methods This study was a cross-sectional and convenient sampling study conducted among patients undergoing IVF-ET from January to June 2019. Patients were divided into first-time and repeated groups by the number of IVF-ET cycles, and then a questionnaire survey was administered. The questionnaire included demographic information, Herth hope index (HHI) scale, Locke-Wallace short marital-adjustment test scale and social support rating scale. Multiple linear regression was used to analyse the influencing factors associated with hope levels. Results A total of 298 IVF-ET patients were recruited for the study, including 150 (50.3%) in the first-time cycle group and 148 (49.7%) in the repeated cycle group. The HHI score of the repeated cycle group was significantly lower than that of the first-time cycle group (34.4 ± 3.5 vs. 37.5 ± 3.7, P < 0.001). Multiple linear regression analysis indicated that repeated IVF-ET and age were independently negatively correlated with HHI, with standardized coefficient β values of − 0.895 and − 0.223, respectively (both P < 0.001). High education level (P = 0.002), high monthly income (P = 0.020), high degree of short marital-adjustment test (P < 0.001) and social support rating (P < 0.001) were independently positively correlated with HHI. Conclusion Infertile women undergoing repeated IVF-ET have low hope levels. Maintaining a good marriage adjustment and establishing a good social support and relationship network could effectively improve their hope levels.

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The Effect of Atosiban on Patients With Difficult Embryo Transfers Undergoing In Vitro Fertilization–Embryo Transfer

Reproductive Sciences ◽

10.1177/1933719119831791 ◽

2019 ◽

Vol 26 (12) ◽

pp. 1613-1617 ◽

Cited By ~ 1

Author(s):

Caixia Yuan ◽

Haixia Song ◽

Lingling Fan ◽

Shili Su ◽

Baihua Dong

Keyword(s):

In Vitro Fertilization ◽

Implantation Rate ◽

Clinical Pregnancy ◽

Double Blind Study ◽

Double Blind ◽

Vitro Fertilization ◽

Infertile Women ◽

Cryopreserved Embryos ◽

Ivf Et

The purpose of this study was to evaluate the effect of atosiban on the outcomes of infertile women undergoing in vitro fertilization (IVF) with difficult embryo transfers (ETs). This randomized double-blind study enrolled 204 infertile women with difficult ETs during IVF treatment between June 2014 and June 2018. According to a computer-generated randomization list, participants were randomized into placebo (n = 102) and atosiban (n = 102) groups. In atosiban group, atosiban with a total dose of 37.5 mg was administered. All of the patients underwent IVF-ET using cryopreserved embryos. The clinical pregnancy rate per cycle and implantation rate per transfer (45.1% and 26.5%) in atosiban group were significantly higher than those of placebo group (15.6% and 9.7%, respectively; P < .05). This study showed that administration of atosiban during ET was extraordinarily effective for patients with difficult transfers.

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