Ischemic stroke and peripheral arterial thromboembolism in a patient with Crohn's disease: A case presentation

2008 ◽  
Vol 266 (1-2) ◽  
pp. 177-179 ◽  
Author(s):  
Tobias Freilinger ◽  
Eva Riedel ◽  
Markus Holtmannspötter ◽  
Martin Dichgans ◽  
Nils Peters
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Shin Emoto ◽  
Shigenori Homma ◽  
Tadashi Yoshida ◽  
Nobuki Ichikawa ◽  
Yoichi Miyaoka ◽  
...  

Abstract Background The improved prognosis of Crohn’s disease may increase the opportunities of surgical treatment for patients with Crohn’s disease and the risk of development of colorectal cancer. We herein describe a patient with Crohn’s disease and a history of multiple surgeries who developed rectal stump carcinoma that was treated laparoscopically and transperineally. Case presentation A 51-year-old man had been diagnosed with Crohn’s disease 35 years earlier and had undergone several operations for treatment of Crohn’s colitis. Colonoscopic examination was performed and revealed rectal cancer at the residual rectum. The patient was then referred to our department. The tumor was diagnosed as clinical T2N0M0, Stage I. We treated the tumor by combination of laparoscopic surgery and concomitant transperineal resection of the rectum. While the intra-abdominal adhesion was dissected laparoscopically, rectal dissection in the correct plane progressed by the transperineal approach. The rectal cancer was resected without involvement of the resection margin. The duration of the operation was 3 h 48 min, the blood loss volume was 50 mL, and no intraoperative complications occurred. The pathological diagnosis of the tumor was type 5 well- and moderately differentiated adenocarcinoma, pT2N0, Stage I. No recurrence was evident 3 months after the operation, and no adjuvant chemotherapy was performed. Conclusion The transperineal approach might be useful in patients with Crohn’s disease who develop rectal cancer after multiple abdominal surgeries.


2011 ◽  
Vol 5 (2) ◽  
pp. 169-170 ◽  
Author(s):  
Geraldine E. Murature Stordiau ◽  
Javier Suárez Alecha ◽  
Silvia Goñi ◽  
José Manuel Zozaya ◽  
Roberto Centeno ◽  
...  

1996 ◽  
Vol 22 (2) ◽  
pp. 141-143 ◽  
Author(s):  
Dror Mevorach ◽  
Yael Goldberg ◽  
J. Moshe Gomori ◽  
Daniel Rachmilewitz

2017 ◽  
Vol 41 (S1) ◽  
pp. S469-S469
Author(s):  
I. Christodoulou ◽  
F. Tsiompanou ◽  
N. Peitsidis ◽  
G. Dounias ◽  
I. Tsakiridis ◽  
...  

Aim of this study is to present the extraordinary case of a 45-year-old man with very short bowel syndrome and ileostomy, who is currently engaged in a long hospitalization module of life because of the constant need for parenteral nutrition which he has developed due to Crohn's disease treatments. Case presentation: A Russian young man, with low education, a borderline intellectual functioning and a low socio-economic status, was operated numerous times due to breakouts of Crohn's disease. For the last year, he stays mostly in the hospital. Practically he needs constant intravenous parenteral nutrition due to his very short bowel syndrome, otherwise he cannot live outside the hospital. The patient was advised by his surgeon to eat any kind of food but had the limitation to drink not more than 500 ml of water per day, (the rest of water was taken IV). During the first months, the patient seemed willing to do anything needed, but when he started to get tired, he started to drink more than 2 litres of water per day, ignoring his doctor's advice. One of his main problems was that he was able to see that eggs, meat and other food he was eating were very soon appearing in the ileostomy bag and this led him to think that he would die soon. Neither the patient himself nor his wife and relatives asked for help from supervisory bodies of the National Health System and are not at all aware of his need for transplantation.Disclosure of interestThe authors have not supplied their declaration of competing interest.


Author(s):  
Shohei Eto ◽  
Kozo Yoshikawa ◽  
Takashi Iwata ◽  
Jun Higashijima ◽  
Takuya Tokunaga ◽  
...  

Introduction: Crohn's disease (CD) is a chronic inflammatory bowel disease, which affect the entire gastrointestinal tract. Treatment basis for CD is medication to control the inflammation and relieve the symptoms. CD patients often require surgery at some points of their lifetime for complications, treatment-resistant, and side effects of medication. However, the postoperative recurrences are common. To reduce the anastomotic troubles, several types of anastomosis were investigated. Kono-S anastomosis, an antimesenteric functional end-to-end handsewn anastomosis, was introduced in order to prevent the restenosis caused by the recurrence of CD in 2010. Kono-S anastomosis is expected lower susceptibility to mechanical distortions due to the stability provided by the "supporting column". We herein report the two cases of CD which was performed Kono-S anastomosis. The important of these cases are that Kono-S anastomosis is useful to prevent the restenosis caused by the recurrence. Case presentation: The first patient was 26-year-old man, who had suffered from CD for 9 years. Computed tomography (CT) showed inflammation and stenosis at ileocecum, fistula between terminal ileum and sigmoid colon, and 3cm of intraperitoneal abscess. We performed ileocecal resection and Kono-S anastomosis. The second patient was 25-year-old woman who had suffered from CD for 8 years. CT showed inflammation and stenosis at ileocecum, and retroperitoneal abscess. We performed ileocecal resection and Kono-S anastomosis. Both patients don't have the recurrence after surgery. Conclusion: Kono-S anastomosis may be effective for preventing the recurrence at anastomotic site in CD patients.


2010 ◽  
Vol 68 (4) ◽  
pp. 651-652 ◽  
Author(s):  
Marcos C Lange ◽  
Laura N Zamproni ◽  
Vera Braatz ◽  
Artur F Fernandes ◽  
Viviane F Zetola ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Toshihiko Kakiuchi ◽  
Sakiko Kimura ◽  
Motohiro Esaki ◽  
Muneaki Matsuo

Background: Although the biological agent ustekinumab (UST) is reported to be effective for Crohn's disease (CD) in pediatric as well as adult patients, data on the efficacy and safety of UST in pediatric patients with CD are limited. Here, we describe the case of a pediatric patient who showed an allergic reaction to UST after subcutaneous (SC) maintenance injections but not immediately after initial intravenous (IV) injection.Case Presentation: A 9-year-old boy presented to our hospital with diarrhea lasting 2 years and weight loss, leading to the diagnosis of CD. After prednisolone (PSL) was tapered and discontinued, he promptly relapsed. According to our institution's protocol, we introduced the biological agent infliximab (IFX) with premedication. Coughing and vomiting was observed after the second dose of IFX and it was changed to adalimumab (ADA). However, the effect of ADA gradually disappeared after 18 months; therefore, it was discontinued and he was treated using UST. The first IV UST dose was given after administering hydrocortisone (HDC), an antiallergic and antipyretic analgesic, as premedication, and no obvious adverse reaction was observed. After 8 weeks, UST was subcutaneously injected without premedication. The patient then complained of nausea, dizziness, and headache within 15 min of UST administration. Therefore, for the third dose of UST, HDC was administered again as premedication. However, nausea, dizziness, and headache presented 10 min after UST administration, resulting in discontinuation of further UST treatment.Conclusion: Careful distinction between “true” infusion-related reactions (IRRs) and anaphylaxis or allergic reactions is necessary to determine whether biological agents can be continued after the development of “so-called” IRRs. For true IRRs, it may be possible to continue using the biological agent with appropriate premedication; however, in cases of anaphylaxis, the biological agent itself should be changed.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hawani Sasmaya Prameswari ◽  
Iswaree Devi Balakrishnan ◽  
Chun Yuan Khoo ◽  
Loon Yee Teo ◽  
Lihua Laura Chan ◽  
...  

Abstract Background Acute perimyocarditis is a rare extra-intestinal manifestation in Crohn’s disease which required multimodality imaging to confirm the diagnosis. Here we present a case of acute perimyocarditis as the first presentation of Crohn’s disease. To date, this is the first case presentation reporting the use of 18F-FDG PET/CT Scan for diagnosing such condition. Case presentation A 25-year-old male presented to our hospital with severe persistent pleuritic sharp left-sided chest pain. This was his second hospital admission in the past 4 months for chest pain and diarrhea. At the first hospitalization, he was diagnosed with viral perimyocarditis and irritable bowel syndrome. Laboratory findings, electrocardiogram, and cardiac magnetic resonance imaging results confirm the diagnostic of perimyocarditis. Virology, bacteriology, parasitology, and autoimmune evaluations were unremarkable. Colonoscopy, colorectal biopsy, and 18FGD PET findings confirmed manifestation of perimyocarditis, Crohn’s disease, and negative for sarcoidosis. Conclusions Looking at the overall clinical picture and investigation results of colonoscopy, colorectal biopsy findings, as well as multi-modality imaging with echocardiography, 18FDG PET—scan and CMRI, the patient was diagnosed to have perimyocarditis attending Chron’s disease flare up as a rare extra-intestinal manifestation.


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