scholarly journals Prophalaxis of incidence of deep vein thrombosis (VTE) in lower limbs after total knee arthroplasty (TKA) in patients with knee osteoarthritis by eicosapentaenoic acid (EPA) administration – a case-control study

2018 ◽  
Vol 26 ◽  
pp. S282
Author(s):  
J. Shiozawa ◽  
M. Ishijima ◽  
H. Kaneko ◽  
M. Nagayama ◽  
M. Shimizu ◽  
...  
2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Dai Xiaoyu ◽  
Chen Kai ◽  
Huang Zhihui ◽  
Li Huan ◽  
Zhang Naidong ◽  
...  

Abstract Background Hemorheological parameters have been confirmed to be related with deep vein thrombosis (DVT). This study is aimed to verify whether preoperative erythrocyte electrophoresis exponent was associated with postoperative deep vein thrombosis (DVT) risk after total knee arthroplasty (TKA) in patients with primary knee osteoarthritis (KOA). Methods From March 2010 to May 2020, a total of 750 consecutive KOA patients who accepted unilateral TKA were enrolled. They were divided into DVT (176 patients) and non-DVT groups (574 patients) according to the examination results of the Doppler ultrasound of deep veins in both lower limbs on postoperative day 3. The Chi-square test, Student’s t test, and multivariate logistic regression analysis were performed to analyze the correlation of erythrocyte electrophoresis exponent and DVT risk in 2 groups. Receiver operating characteristic (ROC) analysis was used to assess predictive value of erythrocyte electrophoresis exponent for DVT. Results A low erythrocyte electrophoresis exponent was a significant risk factor for DVT in patients with primary KOA (p < 0.05), especially in females when stratified by gender (p < 0.05). Conclusions The findings suggest that lower erythrocyte electrophoresis before surgery may be independently associated with a higher post-surgery DVT risk in primary KOA patients. It is necessary to optimize prophylaxis strategies for DVT in these patients.


1996 ◽  
Vol 76 (06) ◽  
pp. 0883-0886 ◽  
Author(s):  
Paolo Simioni ◽  
Paolo Prandoni ◽  
Alberto Burlina ◽  
Daniela Tormene ◽  
Corrado Sardella ◽  
...  

SummaryIn a case-control study, fasting total homocysteinemia was determined in 208 consecutive outpatients who underwent phlebography because of the first episode of clinically suspected deep-vein thrombosis (DVT) of lower limbs. Contrast venography confirmed the clinical suspicion in 60 patients (28.8%). Hyperhomocysteinemia was detected in 15 of the 60 patients with DVT (25.0%), and in 17 of the 148 subjects without thrombosis (11.5%; p = 0.025). The OR for having an acute DVT in patients with hyperhomocysteinemia was 2.6 (95% Cl: 1.1-5.9). It is concluded that high plasma homocysteine levels are significantly associated with DVT in symptomatic patients. Further studies are needed to clarify the clinical implications of this association.


1996 ◽  
Vol 76 (02) ◽  
pp. 187-189 ◽  
Author(s):  
Paolo Simioni ◽  
Paolo Prandoni ◽  
Ezio Zanon ◽  
Maria A Saracino ◽  
Alberta Scudeller ◽  
...  

Summary Background. A definite evidence in favour of an association of deep-vein thrombosis (DVT) with lupus anticoagulant (LA) in patients free from systemic lupus erythematosus is still lacking. Methods. In a case-control study, LA was determined in 176 consecutive outpatients who underwent phlebography because of the first episode of clinically suspected DVT of lower limbs. The association between DVT and LA was described using odds ratios (OR). Results. Contrast venography confirmed the clinical suspicion in 59 patients (33.5%). LA was detected in 5 of the 59 patients with DVT (8.5%), and in none of the 117 subjects with normal venogram (P = 0.007). The OR for having an acute DVT in patients with LA was 10.7 (95% CI: 1.2-94.2). Conclusions. LA is significantly associated with DVT in symptomatic patients. Further studies are needed to establish the clinical implications of this association.


2010 ◽  
Vol 8 (8) ◽  
pp. 1874-1876 ◽  
Author(s):  
Y. I. G. V. TICHELAAR ◽  
H. M. KNOL ◽  
A. B. MULDER ◽  
J. C. KLUIN-NELEMANS ◽  
W. M. LIJFERING

Sign in / Sign up

Export Citation Format

Share Document