scholarly journals Response to: Losina E. Why past research successes do not translate to clinical reality: gaps in evidence on exercise program efficiency. osteoarthritis and cartilage 2019;27:1–2

2019 ◽  
Vol 27 (7) ◽  
pp. e7-e8 ◽  
Author(s):  
L.R. Swaithes ◽  
K.S. Dziedzic ◽  
E. Cottrell ◽  
J.G. Quicke
Keyword(s):  
Exercise Program ◽  
Past Research ◽  
Program Efficiency ◽  
Clinical Reality ◽  
And Cartilage

scholarly journals Effects of photobiomodulation and a physical exercise program on the expression of inflammatory and cartilage degradation biomarkers and functional capacity in women with knee osteoarthritis: a randomized blinded study

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Patricia Gabrielli Vassão ◽  
Ana Carolina Flygare de Souza ◽  
Raquel Munhoz da Silveira Campos ◽  
Livia Assis Garcia ◽  
Helga Tatiana Tucci ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Knee Osteoarthritis ◽  
Functional Capacity ◽  
Exercise Program ◽  
Cartilage Degradation ◽  
Post Treatment ◽  
Joint Disease ◽  
Control Group ◽  
Knee Oa ◽  
And Cartilage

Abstract Background The knee osteoarthritis (OA) is a joint disease characterized by degradation of articular cartilage that leads to chronic inflammation. Exercise programs and photobiomodulation (PBM) are capable of modulating the inflammatory process of minimizing functional disability related to knee OA. However, their association on the concentration of biomarkers related to OA development has not been studied yet. The aim of the present study is to investigate the effects of PBM (via cluster) with a physical exercise program in functional capacity, serum inflammatory and cartilage degradation biomarkers in patients with knee OA. Methods Forty-two patients were randomly allocated in 3 groups: ESP: exercise + sham PBM; EAP: exercise + PBM and CG: control group. Six patients were excluded before finished the experimental period. The analyzed outcomes in baseline and 8-week were: the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) and the evaluation of serum biomarkers concentration (IL-1β, IL-6, IL-8, IL-10 e TNF-α, and CTX-II). Results An increase in the functional capacity was observed in the WOMAC total score for both treated groups (p < 0.001) and ESP presents a lower value compared to CG (p < 0.05) the 8-week post-treatment. In addition, there was a significant increase in IL-10 concentration of EAP (p < 0.05) and higher value compared to CG (p < 0.001) the 8-week post-treatment. Moreover, an increase in IL-1β concentration was observed for CG (p < 0.05). No other difference was observed comparing the other groups. Conclusion Our data suggest that the physical exercise therapy could be a strategy for increasing functional capacity and in association with PBM for increasing IL-10 levels in OA knee individuals. Trial registration: ReBEC (RBR-7t6nzr).

Nonhuman sequence learning findings argue against Hoerl and McCormack's two systems of temporal cognition

2019 ◽  
Vol 42 ◽  
Author(s):  
Benjamin J. De Corte ◽  
Edward A. Wasserman
Keyword(s):  
Sequence Learning ◽  
Past Research ◽  
Ordinal Position ◽  
Temporal Cognition ◽  
Two Systems

Abstract Hoerl & McCormack propose that animals learn sequences through an entrainment-like process, rather than tracking the temporal addresses of each event in a given sequence. However, past research suggests that animals form “temporal maps” of sequential events and also comprehend the concept of ordinal position. These findings suggest that a clarification or qualification of the authors’ hypothesis is needed.

Cytokine synergy, collagenases and cartilage collagen breakdown

2003 ◽  
Vol 70 ◽  
pp. 125-133 ◽  
Author(s):  
Tim E. Cawston ◽  
Jenny M. Milner ◽  
Jon B. Catterall ◽  
Andrew D. Rowan
Keyword(s):  
Matrix Metalloproteinases ◽  
Inflammatory Cytokines ◽  
Activator Protein 1 ◽  
Activator Protein ◽  
And Cartilage ◽  
Pro Inflammatory Cytokines

We have investigated proteinases that degrade cartilage collagen. We show that pro-inflammatory cytokines act synergistically with oncastatin M to promote cartilage collagen resorption by the up-regulation and activation of matrix metalloproteinases (MMPs). The precise mechanisms are not known, but involve the up-regulation of c-fos, which binds to MMP promoters at a proximal activator protein-1 (AP-1) site. This markedly up-regulates transcription and leads to higher levels of active MMP proteins.

Effects of a 6-Week Straw Phonation in Water Exercise Program on the Aging Voice

2020 ◽  
Vol 63 (4) ◽  
pp. 1018-1032
Author(s):  
Chia-Hsin Wu ◽  
Roger W. Chan
Keyword(s):  
Acoustic Analysis ◽  
Vocal Tract ◽  
Exercise Program ◽  
Analysis Of Covariance ◽  
Elderly Subjects ◽  
Control Group ◽  
Perceptual Evaluation ◽  
Positive Effects ◽  
Aging Voice ◽  
Before And After

Purpose Semi-occluded vocal tract (SOVT) exercises with tubes or straws have been widely used for a variety of voice disorders. Yet, the effects of longer periods of SOVT exercises (lasting for weeks) on the aging voice are not well understood. This study investigated the effects of a 6-week straw phonation in water (SPW) exercise program. Method Thirty-seven elderly subjects with self-perceived voice problems were assigned into two groups: (a) SPW exercises with six weekly sessions and home practice (experimental group) and (b) vocal hygiene education (control group). Before and after intervention (2 weeks after the completion of the exercise program), acoustic analysis, auditory–perceptual evaluation, and self-assessment of vocal impairment were conducted. Results Analysis of covariance revealed significant differences between the two groups in smoothed cepstral peak prominence measures, harmonics-to-noise ratio, the auditory–perceptual parameter of breathiness, and Voice Handicap Index-10 scores postintervention. No significant differences between the two groups were found for other measures. Conclusions Our results supported the positive effects of SOVT exercises for the aging voice, with a 6-week SPW exercise program being a clinical option. Future studies should involve long-term follow-up and additional outcome measures to better understand the efficacy of SOVT exercises, particularly SPW exercises, for the aging voice.

How Sexual Objectification Generates Dehumanization in Western and Eastern Cultures

2018 ◽  
Vol 77 (2) ◽  
pp. 69-82 ◽  
Author(s):  
Robin Wollast ◽  
Elisa Puvia ◽  
Philippe Bernard ◽  
Passagorn Tevichapong ◽  
Olivier Klein
Keyword(s):  
Social Perception ◽  
Past Research ◽  
Objectification Theory ◽  
Southeast Asian ◽  
Sexual Objectification ◽  
Intense Pain ◽  
Eastern Cultures ◽  
Theory Research ◽  
Self Objectification ◽  
Asian Sample

Abstract. Ever since Fredrickson and Roberts (1997) proposed objectification theory, research on self-objectification and – by extension – other-objectification has experienced a considerable expansion. However, most of the studies on sexual objectification have been conducted solely in Western populations. This study investigates whether the effect of target sexualization on social perception differs as a function of culture (Western vs. Eastern). Specifically, we asked a Western sample (Belgian, N = 62) and a Southeast Asian sample (Thai, N = 98) to rate sexualized versus nonsexualized targets. We found that sexual objectification results in dehumanization in both Western (Belgium) and Eastern (Thailand) cultures. Specifically, participants from both countries attributed less competence and less agency to sexualized than to nonsexualized targets, and they reported that they would administer more intense pain to sexualized than to nonsexualized targets. Thus, building on past research, this study suggests that the effect of target sexualization on dehumanization is a more general rather than a culture-specific phenomenon.

Feasibility of an Exercise Program for Older Depressive Inpatients

GeroPsych ◽  
2015 ◽  
Vol 28 (4) ◽  
pp. 163-171 ◽  
Author(s):  
Andreas Heissel ◽  
Anou Vesterling ◽  
Stephanie A. White ◽  
Gunnar Kallies ◽  
Diana Behr ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Pilot Trial ◽  
Exercise Program ◽  
Exercise Group ◽  
Neurocognitive Functioning ◽  
Control Group ◽  
Active Control Group ◽  
Major Depressive ◽  
Older Inpatients ◽  
Relaxation Exercises

Abstract. Twelve older inpatients (M age = 66.8) with Major Depressive Disorder (MDD) participated in this controlled pilot trial either in a physical exercise group (PEG; n = 6; aerobic, strength, and coordination exercises) or an active control group (ACG; n = 6; relaxation exercises) twice a week for four weeks. While depressive symptoms decreased in both groups, reduction of symptoms was significantly larger in the PEG. However, the PEG had higher BDI scores compared to the ACG at pretest. Neurocognitive functioning and brain-derived neurotrophic factor (BDNF) concentration did not change significantly. A four-week exercise program may be a feasible adjunct therapy in older MDD patients but the efficacy of the program needs to be proven with larger samples.

Individual Differences and Hemispheric Asymmetry While Processing Emotional Words

2014 ◽  
Vol 35 (3) ◽  
pp. 137-143 ◽  
Author(s):  
Lindsay M. Niccolai ◽  
Thomas Holtgraves
Keyword(s):  
Individual Differences ◽  
Hemispheric Asymmetry ◽  
Past Research ◽  
Decision Task ◽  
Depression And Anxiety ◽  
Hemispheric Differences ◽  
Affective Valence ◽  
Emotional Words ◽  
Emotion Words ◽  
The Right

This research examined differences in the perception of emotion words as a function of individual differences in subclinical levels of depression and anxiety. Participants completed measures of depression and anxiety and performed a lexical decision task for words varying in affective valence (but equated for arousal) that were presented briefly to the right or left visual field. Participants with a lower level of depression demonstrated hemispheric asymmetry with a bias toward words presented to the left hemisphere, but participants with a higher level of depression displayed no hemispheric differences. Participants with a lower level of depression also demonstrated a bias toward positive words, a pattern that did not occur for participants with a higher level of depression. A similar pattern occurred for anxiety. Overall, this study demonstrates how variability in levels of depression and anxiety can influence the perception of emotion words, with patterns that are consistent with past research.

Perception of Emotional Expressions in Adults

2016 ◽  
Vol 37 (1) ◽  
pp. 16-23 ◽  
Author(s):  
Chit Yuen Yi ◽  
Matthew W. E. Murry ◽  
Amy L. Gentzler
Keyword(s):  
Facial Expressions ◽  
Negative Mood ◽  
Emotion Perception ◽  
State Level ◽  
Past Research ◽  
Negative Emotionality ◽  
Basic Emotions ◽  
Perceived Intensity ◽  
Trait Level ◽  
Facial Expressions Of Emotion

Abstract. Past research suggests that transient mood influences the perception of facial expressions of emotion, but relatively little is known about how trait-level emotionality (i.e., temperament) may influence emotion perception or interact with mood in this process. Consequently, we extended earlier work by examining how temperamental dimensions of negative emotionality and extraversion were associated with the perception accuracy and perceived intensity of three basic emotions and how the trait-level temperamental effect interacted with state-level self-reported mood in a sample of 88 adults (27 men, 18–51 years of age). The results indicated that higher levels of negative mood were associated with higher perception accuracy of angry and sad facial expressions, and higher levels of perceived intensity of anger. For perceived intensity of sadness, negative mood was associated with lower levels of perceived intensity, whereas negative emotionality was associated with higher levels of perceived intensity of sadness. Overall, our findings added to the limited literature on adult temperament and emotion perception.

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