scholarly journals Radiographic hand osteoarthritis and worsening of mri-based tibiofemoral osteoarthritis-related structural damage, data from the OAI study

2020 ◽  
Vol 28 ◽  
pp. S377
Author(s):  
A. Haj-Mirzaian ◽  
R. Kwee ◽  
A. Guermazi ◽  
F. Roemer ◽  
S. Demehri
Keyword(s):  
Structural Damage ◽  
Hand Osteoarthritis ◽  
Damage Data ◽  
Tibiofemoral Osteoarthritis

A macroseismic study and the implications of structural damage of two recent major earthquakes in the Jordan Rift

1977 ◽  
Vol 67 (6) ◽  
pp. 1607-1613
Author(s):  
M. Vered ◽  
H. L. Striem
Keyword(s):  
Quantitative Analysis ◽  
Coastal Plain ◽  
Rift Valley ◽  
Structural Damage ◽  
Macroseismic Data ◽  
Upper Crust ◽  
Structural Trend ◽  
Isoseismal Lines ◽  
Damage Data ◽  
Instrumental Records

abstract A detailed macroseismic study of the July 11, 1927 earthquake was carried out. A quantitative analysis of damage data provided a correlation for estimating (MM) intensities: I = 6.4 + 1.2 log (percentage of damaged houses). Using axis lengths and areas bounded by the ensuing isoseismal lines, the depth (16 to 28 km) of the event was estimated, and its probable epicenter located near Damiya bridge on the Jordan river. A comparison with the equivalent parameters, inferred from instrumental records, shows agreement between both sets of results and thus confirms the validity of the approach used in the macroseismic study. The same procedure of studying macroseismic data was applied to an earlier (January 1, 1837) destructive earthquake. It was found that this latter event orginated in the upper crust, eastward of Safed, with a 6.25 to 6.5 magnitude. The isoseismals of both these major earthquakes are elongated in a north-south direction, along the major structural trend in the area. The southern coastal plain of Israel seems generally less vulnerable to Jordan Rift Valley earthquakes than inland regions of similar epicentral distances, though local pockets of anomalous intensities are observed for both earthquakes.

scholarly journals 1511 A Review of Non-Surgical Management of Hand Osteoarthritis

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
J Shah
Keyword(s):  
Hyaluronic Acid ◽  
Conservative Management ◽  
Structural Damage ◽  
Symptomatic Relief ◽  
Current Treatment ◽  
Hand Osteoarthritis ◽  
Loss Of Function ◽  
Inclusion Criteria ◽  
Management Options ◽  
Surgical Interventions

Abstract Introduction Hand osteoarthritis (OA) is a common musculoskeletal condition leading to pain and loss of function. Current treatment aims to target the symptoms of hand OA involving a combination of non-surgical and surgical interventions. During the COVID-19 pandemic, there has been a renewed interest in conservative management. The purpose of this article is to review non-surgical therapies in hand OA, their mechanism of action and efficacy. Method An online search of PubMed for articles between 1st January 2004- 1st February 2020 was performed according to specific terms and agreed inclusion criteria. Results The search produced 289 results of which 28 met the inclusion criteria comprising 13 RCTs, 8 systematic reviews, 5 clinical trials and 2 international guidelines. Conclusions Topical NSAIDs remain first-line pharmacological agents in the management of hand OA. Increasingly, oral NSAIDs have been recommended however their use must be balanced against their potential adverse effects. Supplementation with chondroitin sulfate may help to delay the structural damage in hand OA, which may reduce the need for oral NSAIDs. Intra-articular injections of hyaluronic acid and corticosteroids are effective treatments and provide longer symptomatic relief, additionally hyaluronic acid may improve function over a longer period of time. Targeted hand exercises are widely recommended however may only provide short-term improvements and vary according to the different subtypes of hand OA. In summary, there are multiple conservative management options for hand OA which should be considered prior to operative intervention given the current restrictions on surgical practice.

scholarly journals The OMERACT Ultrasound Task Force — Status and Perspectives

2011 ◽  
Vol 38 (9) ◽  
pp. 2063-2067 ◽  
Author(s):  
ESPERANZA NAREDO ◽  
RICHARD J. WAKEFIELD ◽  
ANNAMARIA IAGNOCCO ◽  
LENE TERSLEV ◽  
EMILIO FILIPPUCCI ◽  
...  
Keyword(s):  
Systematic Review ◽  
Structural Damage ◽  
Task Force ◽  
Interobserver Reliability ◽  
Research Priorities ◽  
Scoring Systems ◽  
Added Value ◽  
Future Research ◽  
Hand Osteoarthritis ◽  
Future Research Agenda

This article reports the most recent work of the Outcome Measures in Rheumatology (OMERACT) Ultrasound Task Force, and highlights the future research priorities discussed at the OMERACT 10 meeting. Results of the following studies were presented: (1) intra- and interobserver reliability of ultrasound detecting and scoring synovitis in different joints of patients with rheumatoid arthritis (RA); (2) systematic review of previous ultrasound scoring systems of synovitis in RA; (3) enthesitis systematic review and Delphi definition exercise in spondyloarthritis enthesitis; (4) enthesitis intra- and interobserver reliability exercise; and (5) Delphi definition exercise in hand osteoarthritis, and reliability exercises. Study conclusions were discussed, and a future research agenda was approved, notably further validation of an OMERACT ultrasound global synovitis score (GLOSS) in RA, emphasizing the importance of testing feasibility, predictive value, and added value over standard clinical variables. Future research areas will include validating scoring systems for enthesitis and osteoarthritis, and testing the metric qualities of ultrasound for evaluating tenosynovitis and structural damage in RA.

Report from the OMERACT Hand Osteoarthritis Working Group: Set of Core Domains and Preliminary Set of Instruments for Use in Clinical Trials and Observational Studies

2015 ◽  
Vol 42 (11) ◽  
pp. 2190-2197 ◽  
Author(s):  
Margreet Kloppenburg ◽  
Pernille Bøyesen ◽  
A. Willemien Visser ◽  
Ida K. Haugen ◽  
Maarten Boers ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Observational Studies ◽  
Structural Damage ◽  
Contextual Factors ◽  
Future Research ◽  
Hand Osteoarthritis ◽  
Structure Modification ◽  
Core Domain ◽  
Core Set ◽  
Literature Reviews

Objective.During OMERACT 12, a workshop was held with the aim to endorse a core set of domains for 3 settings: clinical trials of symptom and structure modification and observational studies. Additional goals were to endorse a core set of contextual factors for these settings, and to define preliminary instruments for each core domain. Finally, an agenda for future research in hand osteoarthritis (OA) was to be proposed.Methods.Literature reviews of preliminary instruments for each core domain of the proposed core set for hand OA in the settings described above. Literature review of radiographic scoring methods and modern imaging in hand OA were also performed. Proposed contextual factors for a core set were identified through 2 Delphi exercises with participation of hand OA experts, patient partners, and OMERACT participants.Results.Results from Delphi exercises and systematic literature reviews were presented and discussed. It was agreed that a preliminary core domain set for the setting clinical trials of symptom modification should contain at least “pain, physical function, patient global assessment, joint activity and hand strength.” The settings clinical trial of structure modification and observational studies would in addition include structural damage. Preliminary instruments for the proposed domains were agreed on. A list of prioritized contextual factors was defined and endorsed for further research. A research agenda was proposed for domain instrument validation according to the OMERACT Filter 2.0.Conclusion.Preliminary core sets for clinical trials of symptom and structure modification and observational studies in hand osteoarthritis, including preliminary instruments and contextual factors, were agreed upon during OMERACT 12.

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