Porcine follicular fluids: Comparison of solid-phase extraction and matrix solid-phase dispersion for the GC–MS determination of hormones during follicular growth

2007 ◽  
Vol 44 (3) ◽  
pp. 711-717 ◽  
Author(s):  
F. Bianchi ◽  
M. Careri ◽  
A. Mangia ◽  
M. Musci ◽  
S.E. Santini ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Solid Phase ◽  
Phase Extraction ◽  
Follicular Growth ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
Follicular Fluids

scholarly journals Simultaneous determination of 223 pesticides in tobacco by GC with simultaneous electron capture and nitrogen-phosphorous detection and mass spectrometric confirmation

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Bozena Lozowicka ◽  
Ewa Rutkowska ◽  
Izabela Hrynko
Keyword(s):  
Solid Phase Extraction ◽  
Solid Phase ◽  
Mass Spectrometric ◽  
Phase Extraction ◽  
Dispersive Solid Phase Extraction ◽  
Graphitized Carbon ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
Primary Secondary Amine

AbstractLSE (liquid-solid extraction), MSPD (matrix solid phase dispersion) and QuEChERS (quick, easy, cheap, effective, rugged and safe) extractions followed by GC-μECD/NPD to determine 223 pesticide residues in tobacco simultaneously were developed and compared. The identities of ten model pesticides were confirmed by GC-MS/MS. The type and amount of dispersant (Florisil, silica gel and alumina), sample mass, cleanup adsorbent, and the eluent (hexane, acetone and acetonitrile) were optimized. Linearity, recovery, LOQ, LOD, and matrix effect were compared. Most recoveries were 71−120% (RSD < 18%). LOD and LOQ were much lower than the CORESTA GRLs. The best method was QuEChERS: acetonitrile extraction and dispersive solid-phase extraction using primary-secondary amine and graphitized carbon.

scholarly journals Sample Preparation for Determination of Macrocyclic Lactone Mycotoxins in Fish Tissue, Based on On-Line Matrix Solid-Phase Dispersion and Solid-Phase Extraction Cleanup Followed by Liquid Chromatography/Tandem Mass Spectrometry

2003 ◽  
Vol 86 (4) ◽  
pp. 729-736 ◽  
Author(s):  
Aldo Laganà ◽  
Alessandro Bacaloni ◽  
Maryanna Castellano ◽  
Roberta Curini ◽  
Ilaria De Leva ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Macrocyclic Lactone ◽  
Solid Phase ◽  
Tandem Mass ◽  
Phase Extraction ◽  
Neutral Alumina ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion ◽  
On Line

Abstract A new method based on matrix solid-phase dispersion (MSPD) on-line with a solid-phase extraction (SPE) cleanup process followed by liquid chromatography with tandem mass spectrometry (LC/MS/MS) is presented for the determination of 3 macrocyclic lactone mycotoxins in fish tissues: zearalenone, α-zearalenol, and β-zearalenol. The sample was prepared in a device that used a reversed-phase material (C18) or a normal-phase material (neutral alumina) as a matrix dispersing agent, and a graphitized carbon black cartridge was used for sequential cleanup by SPE. LC/MS/MS was used for selective determination. Isocratic elution with acetonitrile–methanol–water was used for LC separation; for MS/MS, 2 types of interfaces (a pneumatically assisted electrospray ionization interface or an atmospheric pressure chemical ionization interface) were evaluated and compared in terms of the intensity of the total ion current produced by each analyte. The use of highly selective MSPD on-line with SPE for sample preparation before analysis allowed the removal of interfering matrix compounds `present in tissue extracts that would otherwise cause severeionization suppression of zearalenone and its metabolites during the ionization process. Average recoveries at 100 ng/g were between 83 and 103% with C18 and ≥67% with neutral alumina; the relative standard deviations were &lt;11% with C18 and &lt;18% with alumina. The limits of detection ranged from 0.1 to 1.0 ng/g. Sample preparation is simple to perform, no special technical equipment is required, and solvent volumes are minimal.

Solid-phase extraction versus matrix solid-phase dispersion: Application to white grapes

Talanta ◽  
2007 ◽  
Vol 74 (1) ◽  
pp. 20-31 ◽  
Author(s):  
M.S. Dopico-García ◽  
P. Valentão ◽  
A. Jagodziñska ◽  
J. Klepczyñska ◽  
L. Guerra ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Solid Phase ◽  
Phase Extraction ◽  
Matrix Solid Phase Dispersion ◽  
Phase Dispersion
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