Highly Sensitive Detection of Salvianic Acid A Drug by A Novel Electrochemical Sensor Based on HKUST-1 Loaded on Three-Dimensional Graphene-MWCNT Composite

2021 ◽  
pp. 114389
Author(s):  
Yifei Xing ◽  
Cong Zhang ◽  
Xinyu Chen ◽  
Huimin Zhao ◽  
Zhaojun Guo
Keyword(s):  
Electrochemical Sensor ◽  
Three Dimensional ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

From non-electroactive to electroactive species: highly selective and sensitive detection based on a dual-template molecularly imprinted polymer electrochemical sensor

2017 ◽  
Vol 53 (86) ◽  
pp. 11755-11758 ◽  
Author(s):  
Yunlong Dai ◽  
Xianwen Kan
Keyword(s):  
Electrochemical Sensor ◽  
Molecularly Imprinted Polymer ◽  
Sensitive Detection ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Highly Sensitive ◽  
Electroactive Species ◽  
Electroactive Molecules ◽  
Highly Sensitive Detection

A selective and sensitive detection of non-electroactive and electroactive molecules has been achieved on a dual-template imprinted electrochemical sensor. And the proposed dual-signal strategy can be used for highly sensitive detection of electroactive analytes.

scholarly journals A Three-Dimensional Enormous Surface Area Aluminum Microneedle Array with Nanoporous Structure

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Po Chun Chen ◽  
Sheng Jen Hsieh ◽  
Chien Chon Chen ◽  
Jun Zou
Keyword(s):  
Drug Delivery ◽  
Surface Area ◽  
3D Structure ◽  
Three Dimensional ◽  
Sensitive Detection ◽  
Nanoporous Structure ◽  
Microneedle Array ◽  
Highly Sensitive ◽  
Technology Applications ◽  
Highly Sensitive Detection

We proposed fabricating an aluminum microneedle array with a nanochannel structure on the surface by combining micromachining, electrolyte polishing, and anodization methods. The microneedle array provides a three-dimensional (3D) structure that possesses several hundred times more surface area than a traditional nanochannel template. Therefore, the microneedle array can potentially be used in many technology applications. This 3D microneedle array device can not only be used for painless injection or extraction, but also for storage, highly sensitive detection, drug delivery, and microelectrodes. From the calculation we made, the microneedle array not only increases surface area, but also enlarges the capacity of the device. Therefore, the microneedle array can further be used on many detecting, storing, or drug delivering applications.

scholarly journals Membrane-Based Microwave-Mediated Electrochemical Immunoassay for the In Vitro, Highly Sensitive Detection of Osteoporosis-Related Biomarkers

Sensors ◽  
2018 ◽  
Vol 18 (9) ◽  
pp. 2933 ◽  
Author(s):  
Hye Kim ◽  
Shinobu Sato ◽  
Shigeori Takenaka ◽  
Min-Ho Lee
Keyword(s):  
Type I Collagen ◽  
Three Dimensional ◽  
Sensitive Detection ◽  
Type I ◽  
Electrochemical Immunoassay ◽  
Nylon Membrane ◽  
Standard Equipment ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

Highly sensitive and multiplexed in vitro detection of osteoporosis-related biochemical markers were carried out based on the membrane-based microwave-mediated electrochemical immunoassay (MMeEIA), where we can dramatically reduce the sample preparation time by shortening the incubation time of conjugation to obtain sensitive detection based on three dimensional conjugation of antibodies with target antigens in nylon membrane disk. C-terminal cross-linked telopeptide of type I collagen (CTx), Osteocalcin (OC), parathyroid hormone (PTH), and N-terminal propeptide of type I collagen (P1NP), which can be utilized to monitor the progress of osteoporosis, were quantified using their corresponding antibody immobilized in membranes. Coefficient of variations in this intra- and inter-assays were within 8.0% for all markers. When compared with data obtained from clinically used standard equipment (Roche modular E170), their coefficients of determination, R2 values, are mostly more than 0.9. They show that the results obtained from MMeEIA are in good agreement with that from the conventional clinical instruments.

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