Spontaneous ultra-weak photon emission in correlation to inflammatory metabolism and oxidative stress in a mouse model of collagen-induced arthritis

2017 ◽  
Vol 168 ◽  
pp. 98-106 ◽  
Author(s):  
Min He ◽  
Eduard van Wijk ◽  
Herman van Wietmarschen ◽  
Mei Wang ◽  
Mengmeng Sun ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mouse Model ◽  
Photon Emission ◽  
Collagen Induced Arthritis ◽  
And Oxidative Stress

A multifunctional compound ebselen reverses memory impairment, apoptosis and oxidative stress in a mouse model of sporadic Alzheimer's disease

2019 ◽  
Vol 109 ◽  
pp. 107-117 ◽  
Author(s):  
Franciele Martini ◽  
Suzan Gonçalves Rosa ◽  
Isabella Pregardier Klann ◽  
Bruna Cruz Weber Fulco ◽  
Fabiano Barbosa Carvalho ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Mouse Model ◽  
Memory Impairment ◽  
Sporadic Alzheimer’S Disease ◽  
And Oxidative Stress

Presymptomatic Alterations in Energy Metabolism and Oxidative Stress in the APP23 Mouse Model of Alzheimer Disease

2012 ◽  
Vol 11 (6) ◽  
pp. 3295-3304 ◽  
Author(s):  
Daniela Hartl ◽  
Victoria Schuldt ◽  
Stephanie Forler ◽  
Claus Zabel ◽  
Joachim Klose ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Energy Metabolism ◽  
Alzheimer Disease ◽  
Mouse Model ◽  
App23 Mouse ◽  
And Oxidative Stress

scholarly journals Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Tsuyoshi Shuto ◽  
Shunsuke Kamei ◽  
Hirofumi Nohara ◽  
Haruka Fujikawa ◽  
Yukihiro Tasaki ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mouse Model ◽  
Lung Diseases ◽  
Obstructive Lung Diseases ◽  
And Oxidative Stress

Comicronized PEA and Rutin reduces inflammation and oxidative stress in a mouse model of vascular injury

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Alessio Filippo peritore ◽  
Daniela Impellizzeri ◽  
Enrico Gugliandolo ◽  
Rosalba Siracusa ◽  
Roberta Fusco ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mouse Model ◽  
Vascular Injury ◽  
And Oxidative Stress

scholarly journals Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation

2018 ◽  
Vol 15 (1) ◽  
Author(s):  
Joana Costa d’Avila ◽  
Luciana Domett Siqueira ◽  
Aurélien Mazeraud ◽  
Estefania Pereira Azevedo ◽  
Debora Foguel ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cognitive Impairment ◽  
Mouse Model ◽  
Systemic Inflammation ◽  
Age Related ◽  
And Oxidative Stress

Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced behavioural dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinsonʼs disease

2010 ◽  
Vol 21 (5-6) ◽  
pp. 563-571 ◽  
Author(s):  
Mohammad Moshahid Khan ◽  
Md. Nasrul Hoda ◽  
Tauheed Ishrat ◽  
Ajmal Ahmad ◽  
Mohammad Badruzzaman Khan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mouse Model ◽  
And Oxidative Stress

scholarly journals 17β-Estradiol Attenuates Intracerebral Hemorrhage-Induced Blood–Brain Barrier Injury and Oxidative Stress Through SRC3-Mediated PI3K/Akt Signaling Pathway in a Mouse Model

ASN NEURO ◽  
2021 ◽  
Vol 13 ◽  
pp. 175909142110384
Author(s):  
Han Xiao ◽  
Jianyang Liu ◽  
Jialin He ◽  
Ziwei Lan ◽  
Mingyang Deng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Brain Injury ◽  
Mouse Model ◽  
Intracerebral Hemorrhage ◽  
Signaling Pathway ◽  
Brain Edema ◽  
Akt Signaling ◽  
Neurological Deficits ◽  
Akt Signaling Pathway ◽  
And Oxidative Stress

Estrogen is neuroprotective in brain injury models, and steroid receptor cofactor 3 (SRC3) mediates estrogen signaling. We aimed to investigate whether and how SRC3 is involved in the neuroprotective effects of 17ß-estradiol (E2) in a mouse model of intracerebral hemorrhage (ICH). Ovariectomized female mice were treated with E2 after autologous blood injection-induced ICH. Brain damage was assessed by neurological deficit score, brain water content, and oxidative stress levels. Blood–brain barrier (BBB) integrity was evaluated by Evan's blue extravasation and claudin-5, ZO-1, and occludin levels. SRC3 expression and PI3K/Akt signaling pathway were examined in ICH mice treated with E2. The effect of SRC3 on E2-mediated neuroprotection was determined by examining neurological outcomes in SRC3-deficient mice undergone ICH and E2 treatment. We found that E2 alleviated ICH-induced brain edema and neurological deficits, protected BBB integrity, and suppressed oxidative stress. E2 enhanced SRC3 expression and PI3K-/Akt signaling pathway. SRC3 deficiency abolished the protective effects of E2 on ICH-induced neurological deficits, brain edema, and BBB integrity. Our results suggest that E2 suppresses ICH-induced brain injury and SRC3 plays a critical role in E2-mediated neuroprotection.

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