scholarly journals Longitudinal relationship between maternal distress and pediatric mood symptoms in youth with mood disorders

Author(s):  
Marc J. Weintraub ◽  
Christopher D. Schneck ◽  
Manpreet K. Singh ◽  
Patricia D. Walshaw ◽  
Kiki D. Chang ◽  
...  
2019 ◽  
Vol 65 (4) ◽  
pp. 213-227 ◽  
Author(s):  
Jairo Vinícius Pinto ◽  
Gayatri Saraf ◽  
Christian Frysch ◽  
Daniel Vigo ◽  
Kamyar Keramatian ◽  
...  

Objective: To review the current evidence for efficacy of cannabidiol in the treatment of mood disorders. Methods: We systematically searched PubMed, Embase, Web of Science, PsychInfo, Scielo, ClinicalTrials.gov , and The Cochrane Central Register of Controlled Trials for studies published up to July 31, 2019. The inclusion criteria were clinical trials, observational studies, or case reports evaluating the effect of pure cannabidiol or cannabidiol mixed with other cannabinoids on mood symptoms related to either mood disorders or other health conditions. The review was reported in accordance with guidelines from Preferred Reporting Items for Systematic reviews and Meta-Analyses protocol. Results: Of the 924 records initially yielded by the search, 16 were included in the final sample. Among them, six were clinical studies that used cannabidiol to treat other health conditions but assessed mood symptoms as an additional outcome. Similarly, four tested cannabidiol blended with Δ-9-tetrahydrocannabinol in the treatment of general health conditions and assessed affective symptoms as secondary outcomes. Two were case reports testing cannabidiol. Four studies were observational studies that evaluated the cannabidiol use and its clinical correlates. However, there were no clinical trials investigating the efficacy of cannabidiol, specifically in mood disorders or assessing affective symptoms as the primary outcome. Although some articles point in the direction of benefits of cannabidiol to treat depressive symptoms, the methodology varied in several aspects and the level of evidence is not enough to support its indication as a treatment for mood disorders. Conclusions: There is a lack of evidence to recommend cannabidiol as a treatment for mood disorders. However, considering the preclinical and clinical evidence related to other diseases, cannabidiol might have a role as a treatment for mood disorders. Therefore, there is an urgent need for well-designed clinical trials investigating the efficacy of cannabidiol in mood disorders.


2019 ◽  
Vol 5 (1) ◽  
pp. e000521
Author(s):  
Laura E Keating ◽  
Suzanna Becker ◽  
Katie McCabe ◽  
Jeff Whattam ◽  
Laura Garrick ◽  
...  

BackgroundIndividuals with mood disorders often report lingering health-related quality of life (HRQOL) and social and cognitive impairments even after mood symptoms have improved. Exercise programmes improve mood symptoms in patients, but whether exercise improves functional outcomes in patients with difficult-to-treat mood disorders remains unknown.DesignWe evaluated the impact of a 12-week structured running programme on cognitive, social and quality-of-life outcomes in participants with difficult-to-treat mood disorders.MethodsIn a prospective, open-label study, patients referred to the St Joseph’s Healthcare HamiltonTeam Unbreakablerunning programme for youth and adults with mood disorders completed a comprehensive assessment battery before and after the 12-week exercise intervention.ResultsWe collected preintervention and postintervention data from 18 participants who improved on the general health, vitality, role of emotions, social functioning and mental health (all p≤0.01) HRQOL subscales. Performance improved on cognitive tests that assessed working memory and processing speed (p≤0.04); there were no improvements in complex executive functioning tasks. Regression analyses indicated that younger age, shorter illness duration and reduced bodily pain predicted social and cognitive outcomes.ConclusionParticipation in a group-based, structured running programme was associated with improved HRQOL and social and cognitive function.


2017 ◽  
Vol 48 (6) ◽  
pp. 820-833 ◽  
Author(s):  
Jonah N. Cohen ◽  
M. Taylor Dryman ◽  
Amanda S. Morrison ◽  
Kirsten E. Gilbert ◽  
Richard G. Heimberg ◽  
...  

2020 ◽  
Author(s):  
Sunny H.W. Chan ◽  
Wendy W.K. Chan ◽  
June Y.W. Chao ◽  
Phyllis K.L. Chan

Abstract Background: The goal of this study was to investigate treatment outcome and related intervention processes of mindfulness-based cognitive therapy (MBCT) versus health qigong-based cognitive therapy (HQCT) versus waitlist control (WC) among individuals with mood disorders.Methods: A total of 187 individuals with mood disorders were randomized and allocated into MBCT, HQCT, or WC groups. All participants were assessed at three time points with regard to mood symptoms, physical and mental health status, perceived stress, sleep quality, and self-efficacy. Linear mixed models analysis was used to test the individual growth model by studying the longitudinal data.Results: MBCT and HQCT both produced greater improvements on most outcome measures as compared with WC. Relatively, more reductions of mood symptoms were observed in the HQCT group as compared with the MBCT group. HQCT is more conducive to physical health status whereas MBCT has more favorable mental health outcomes. Individual growth curve models indicated that alternations in perceived stress was the common predictor of mood changes in both intervention groups. Conclusions: The predominant emphasis on physical health in HQCT makes it more acceptable and effective than MBCT as applied in Chinese individuals with mood disorders. The influence of Chinese culture is discussed. Trial registration: HKU Clinical Trials Registry. Identifier: HKUCTR-2558. Registered 21st Nov 2018.


Author(s):  
Eric A. Fertuck ◽  
Megan S. Chesin ◽  
Brian Johnston

Borderline personality disorder (BPD) and mood disorder (MD) can be difficult to differentiate from each other due to several overlapping clinical features. Among BPD symptoms, chronic dysphoria can be mistaken for major depression, while affective instability may be confused with the depressed and elevated mood episodes of bipolar disorder (BD). Conversely, in those with BPD, co-occurring MDs can be difficult to rigorously assess and treat. Even though there is moderate to high co-occurrence between these conditions, BPD and MDs have distinct facets of impulsivity, affective instability, and mood symptoms. Furthermore, BPD, MD, and their co-occurrence predict courses of illness, prognosis, treatment outcomes, and suicide risk. Consequently, thorough assessment and differential diagnosis of these conditions should inform treatment planning and clinical management in both BPD and MD.


CNS Spectrums ◽  
2005 ◽  
Vol 10 (6) ◽  
pp. 461-470 ◽  
Author(s):  
Judith Feld ◽  
Uriel Halbreich ◽  
Sandhya Karkun

AbstractData regarding the increased incidence of psychiatric illness during midlife in women are still conflicting. However, there is a growing consensus that certain groups of women may in fact be at higher risk for mood symptoms and psychiatric disorders during the perimenopausal transition. Mood symptoms during the perimenopause may be related to mood disorders during other periods of hormonal fluctuation throughout a woman's reproductive lifecycle. Elucidating these associations may advance the understanding of mood disorders during the perimenopausal transition. The epidemiology and treatment of perimenopausal mood symptoms compared with the epidemiology and treatment of mood disorders during the late luteal phase of the menstrual cycle, pregnancy, and postpartum. Common risk factors associated with mood disorders during these periods of hormonal changes or instability include poor lifestyle habits, a history of hormonally related mood disorders, stress and negative life events, ethnicity, and comorbidity. Reproductive-related mood disorders also are subject to an improvement in symptoms in response to treatment with selective serotonin reuptake inhibitors. As the morbidity associated with mood disorders during midlife may be quite significant, and as life expectancy continues to increase, recognition, prevention, and treatment of perimenopausal affective illness is becoming increasingly essential.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
S. Aldandashi ◽  
M. Blackman

Introduction:Drug and alcohol addiction is a leading cause of raising health care cost and has adverse effect on peoples health, social and occupational functioning.The purpose of this study was to investigate the prevalence of substance induced psychosis and mood disorders in adolescent population, and to determine what type of substance causing the presentation.Methods:Child psychiatry consults in the emergency department at Royal Alexandra Hospital, Edmonton, Canada during October, November, and December, 2007.Age was 12 to 17 years both sexes. Presenting complaints were either psychosis or mood symptoms. The diagnosis of substance induced disorder was made according to the DSM IV TR. Urine toxicology screen were obtained before discharge from Emergency department for cannabis, amphetamine, and cocaine. Blood test for ETOH was performed.Results:Total number of subjects was 27 patients. 70.37% presented with substance induced mood disorder, 29.62% with substance induced psychosis. For patients with psychosis (8, one was excluded, untested urine) 28.57% the urine test was positive for amphetamine, 42.85% marijuana, 14.28% cocaine, 14.28% negative test. For patients with mood disorder (19, 6 was excluded, untested urine) 76.92% urine was negative for substances, 15.30% blood was positive for ETOH, 7.69% urine was positive for cannabis.Discussion:In this preliminary data, a trend that substance induced mood disorder is more prevalent than substance induced psychosis. Substance is more to cause psychosis than mood disorder. Cannabis use is more than amphetamine and cocaine to produce psychosis. ETOH use is more than Cannabis to produce mood symptoms.


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