Real-world experience of using combinatorial pharmacogenomic test in children and adolescents with depression and anxiety

2021 ◽  
Author(s):  
Anjali Dagar ◽  
Suneela Cherlopalle ◽  
Veena Ahuja ◽  
Lillian Senko ◽  
Robert S. Butler ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Real World ◽  
Depression And Anxiety

scholarly journals Omalizumab in Children and Adolescents with Chronic Urticaria: A 16 Week Real-World Study

2021 ◽  
Vol 147 (2) ◽  
pp. AB26
Author(s):  
Xiaoting Song ◽  
Marcus Maurer ◽  
Yudi Chen ◽  
Miao Yu ◽  
Zuotao Zhao
Keyword(s):  
Children And Adolescents ◽  
Chronic Urticaria ◽  
Real World

Impacts of online and offline Islamophobia

Islamophobia ◽  
2016 ◽  
Author(s):  
Irene Zempi ◽  
Imran Awan
Keyword(s):  
Real World ◽  
Emotional Responses ◽  
Depression And Anxiety ◽  
The Real ◽  
The Relationship

This chapter examines the implications of online/offline Islamophobia for victims including increased feelings of vulnerability, fear and insecurity. Participants also suffered a range of psychological and emotional responses such as low confidence, depression and anxiety. Additionally, participants highlighted the relationship between online and offline Islamophobia, and described living in fear because of the possibility of online threats materialising in the ‘real world’. Many participants reported taking steps to become less ‘visible’ for example by taking the headscarf or face veil off for women and shaving their beards for men.

scholarly journals Blended Care-Cognitive Behavioral Therapy for Depression and Anxiety in Real-World Settings: Pragmatic Retrospective Study (Preprint)

2020 ◽  
Author(s):  
Anita Lungu ◽  
Janie Jihee Jun ◽  
Okhtay Azarmanesh ◽  
Yan Leykin ◽  
Connie E-Jean Chen
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Real World ◽  
Behavioral Therapy ◽  
Anxiety Symptoms ◽  
Cognitive Behavioral ◽  
Depression And Anxiety ◽  
Symptoms Of Depression ◽  
Care Intervention ◽  
Blended Care ◽  
Over Time

BACKGROUND The past few decades saw considerable advances in research and dissemination of evidence-based psychotherapies, yet available treatment resources are not able to meet the high need for care for individuals suffering from depression or anxiety. Blended care psychotherapy, which combines the strengths of therapist-led and internet interventions, can narrow this gap and be clinically effective and efficient, but has rarely been evaluated outside of controlled research settings. OBJECTIVE This study evaluated the effectiveness of a blended care intervention (video-based cognitive behavior therapy and internet intervention) under real-world conditions. METHODS This is a pragmatic retrospective cohort analysis of 385 participants with clinical range depression and/or anxiety symptoms at baseline, measured using Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7), who enrolled in blended care psychotherapy treatment. Participants resided in the United States and had access to the blended care intervention as a mental health benefit offered through their employers. Levels of depression and anxiety were tracked throughout treatment. Hierarchical linear modeling was used to examine the change in symptoms over time. The effects of age, gender, and providers on participants’ symptom change trajectories were also evaluated. Paired sample t-tests were also conducted, and rates of positive clinical change and clinically significant improvement were calculated. RESULTS The average depression and anxiety symptoms at 6 weeks after the start of treatment were 5.94 and 6.57, respectively. There were significant linear effects of time on both symptoms of depression and anxiety (β=–.49, <i>P</i>&lt;.001 and β=–.64, <i>P</i>&lt;.001). The quadratic effect was also significant for both symptoms of depression and anxiety (β=.04, P&lt;.001 for both), suggesting a decelerated decrease in symptoms over time. Approximately 73% (n=283) of all 385 participants demonstrated reliable improvement, and 83% (n=319) recovered on either the PHQ-9 or GAD-7 measures. Large effect sizes were observed on both symptoms of depression (Cohen d=1.08) and of anxiety (d=1.33). CONCLUSIONS Video blended care cognitive behavioral therapy interventions can be effective and efficient in treating symptoms of depression and anxiety in real-world conditions. Future research should investigate the differential and interactive contribution of the therapist-led and digital components of care to patient outcomes to optimize care.

scholarly journals Omalizumab in children and adolescents with chronic urticaria: A 16 week real-world study

2020 ◽  
Author(s):  
Xiaoting Song ◽  
Yu di Chen ◽  
Miao Yu ◽  
Bo Liu ◽  
Zuotao Zhao ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Chronic Urticaria ◽  
Real World

scholarly journals Burden, depression and anxiety in primary caregivers of children and adolescents in renal replacement therapy

2019 ◽  
Vol 41 (3) ◽  
pp. 356-363 ◽  
Author(s):  
Angélica Godoy Torres Lima ◽  
Clécia Cristiane da Silva Sales ◽  
Welton Flávio de Lima Serafim
Keyword(s):  
Renal Replacement Therapy ◽  
Children And Adolescents ◽  
Replacement Therapy ◽  
Primary Caregivers ◽  
Severe Depression ◽  
The Body ◽  
Renal Unit ◽  
Depression And Anxiety ◽  
Negative Consequences ◽  
Cross Sectional

ABSTRACT Introduction: Chronic kidney disease (CKD) is rare in children, but it causes repercussions in several aspects of life, because the disease and treatment cause great changes in the daily lives of the child and his family, increasing the burden on caregivers. Objective: To evaluate the burden of primary caregivers of children and adolescents who undergo renal replacement therapy (RRT). Methods: Cross-sectional, observational study performed at the Pediatric Renal Unit of a school hospital in the Northeast. Forty-nine primary caregivers of pediatric patients with CKD in RRT followed up in our clinic participated in the study. We used validated instruments to assess burden, depression and anxiety. We ran some tests to analyze the findings of burden, depression and anxiety in the sample. Results: Most of the caregivers are the mothers of these children (89.8%), aged between 36 and 45 years (46.9%), have Elementary School education only (55.1%) and reported feeling pain in the body (69.4%), but they did not have chronic disease. The majority of the children have been in RRT from 1 to 3 years (40.8%), aged from 9 to 11 years (30.6%), are male (55.1%), and under hemodialysis (38.8%). The caregivers had a moderate level of burden (2.10), a high prevalence of moderate to severe depression (18.4%) and anxiety (47%), and a strong correlation between burden, depression and anxiety. Conclusions: Caring for a child with CKD is an intense experience, with negative consequences, due to uncertainties about the future and the very care these children require. We need to do something to help these caregivers better manage care, as well as cope with their own feelings.

scholarly journals Assessment and Management of Depression and Anxiety in Children and Adolescents with Epilepsy

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
David Plevin ◽  
Nicholas Smith
Keyword(s):  
Children And Adolescents ◽  
Clinical Management ◽  
Narrative Review ◽  
Anxiety And Depression ◽  
Depression And Anxiety ◽  
Antiepileptic Medication ◽  
Significant Burden ◽  
Patients With Epilepsy ◽  
Paediatric Epilepsy

Anxiety and depression in children and adolescents with epilepsy are common comorbidities which place a significant burden on patients and families and complicate the clinical management of epilepsy. This paper presents a narrative review on the aetiology, phenomenology, assessment, and management of depression and anxiety among paediatric patients with epilepsy. The recognition of affective comorbidity in paediatric epilepsy is limited at present, and the contributory role of antiepileptic medication towards such comorbidity must be considered by clinicians.

scholarly journals Depression and anxiety disorders in children and adolescents with velo-cardio-facial syndrome (VCFS)

2012 ◽  
Vol 21 (7) ◽  
pp. 379-385 ◽  
Author(s):  
Alice Fabbro ◽  
Eleonora Rizzi ◽  
Maude Schneider ◽  
Martin Debbane ◽  
Stephan Eliez
Keyword(s):  
Anxiety Disorders ◽  
Children And Adolescents ◽  
Depression And Anxiety ◽  
Velo Cardio Facial Syndrome
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