Assessment of Quality of Life, Sexual Quality of Life, and Pain Symptoms in Deep Infiltrating Endometriosis Patients With or Without Associated Adenomyosis and the Influence of a Flexible Extended Combined Oral Contraceptive Regimen: Results of a Prospective, Observational Study

Author(s):  
Ana María Alcalde ◽  
María Ángeles Martínez-Zamora ◽  
Meritxell Gracia ◽  
Cristina Ros ◽  
Mariona Rius ◽  
...  
Author(s):  
Justyna Dąbrowska-Bień ◽  
Henryk Skarżyński ◽  
Sebastian Filip Górski ◽  
Piotr Henryk Skarżyński

Abstract Introduction Nasal obstruction is a common symptom in otorhinolaryngological practice. It can impact significantly on the quality of life of the individual. Objective The primary goal of the present study was to evaluate quality of life after septoplasty in adults with nasal obstruction. A secondary goal was to assess the effectiveness of septoplasty. Methods This was a single institution prospective observational study. Patients had experienced septal deviation and symptomatic nasal obstruction with no benefit from medical treatment. There were 51 patients who completed the Nasal Obstruction Symptom Evaluation (NOSE-POL) scale as well as theVisual Analogue Scale (VAS) before undergoing septoplasty, 3 months later, and finally 7 months after surgery. Patients evaluated changes in their nasal obstruction and changes in their quality of life using the Clinical Global Impression Scale (CGI-S). Results There was a significant improvement in nasal obstruction after septoplasty. Before septoplasty, the mean score on NOSE was 60.3 ± 20.4; 3 months after surgery, it was 32.9 ± 16.8; and 7 months after surgery it was 39.6 ± 33.2. The VAS results also proved a significant enhancement in nasal obstruction after septoplasty. Patients reported an improvement in nasal obstruction as well as a positive change in quality of life, confirming the effectiveness of septoplasty. Conclusions In patients with deformed septum, septoplasty contributes to high satisfaction of the patient and a compelling improvement in disease-specific quality of life. The NOSE-POL questionnaire is a useful tool for measuring the outcomes of this procedure.


2018 ◽  
Vol 61 (5) ◽  
pp. 605 ◽  
Author(s):  
Marlon de Freitas Fonseca ◽  
Lilian Carvalho Aragao ◽  
Felipe Ventura Sessa ◽  
Jose Anacleto Dutra de Resende ◽  
Claudio Peixoto Crispi

BMJ Open ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. e023709 ◽  
Author(s):  
Esther MM Van Lieshout ◽  
Daan T Van Yperen ◽  
Margriet E Van Baar ◽  
Suzanne Polinder ◽  
Doeke Boersma ◽  
...  

IntroductionThe Emergency Management of Severe Burns (EMSB) referral criteria have been implemented for optimal triaging of burn patients. Admission to a burn centre is indicated for patients with severe burns or with specific characteristics like older age or comorbidities. Patients not meeting these criteria can also be treated in a hospital without burn centre. Limited information is available about the organisation of care and referral of these patients. The aims of this study are to determine the burn injury characteristics, treatment (costs), quality of life and scar quality of burn patients admitted to a hospital without dedicated burn centre. These data will subsequently be compared with data from patients with<10% total bodysurface area (TBSA) burned who are admitted (or secondarily referred) to a burn centre. If admissions were in agreement with the EMSB, referral criteria will also be determined.Methods and analysisIn this multicentre, prospective, observational study (cohort study), the following two groups of patients will be followed: 1) all patients (no age limit) admitted with burn-related injuries to a hospital without a dedicated burn centre in the Southwest Netherlands or Brabant Trauma Region and 2) all patients (no age limit) with<10% TBSA burned who are primarily admitted (or secondarily referred) to the burn centre of Maasstad Hospital. Data on the burn injury characteristics (primary outcome), EMSB compliance, treatment, treatment costs and outcome will be collected from the patients’ medical files. At 3 weeks and at 3, 6 and 12 months after trauma, patients will be asked to complete the quality of life questionnaire (EuroQoL-5D), and the patient-reported part of the Patient and Observer Scar Assessment Scale (POSAS). At those time visits, the coordinating investigator or research assistant will complete the observer-reported part of the POSAS.Ethics and disseminationThis study has been exempted by the medical research ethics committee Erasmus MC (Rotterdam, The Netherlands). Each participant will provide written consent to participate and remain encoded during the study. The results of the study are planned to be published in an international, peer-reviewed journal.Trial registration numberNTR6565.


2016 ◽  
Vol 13 (9) ◽  
pp. 686-695 ◽  
Author(s):  
Hye Eun Yoon ◽  
Young Joo Kwon ◽  
Ho Cheol Song ◽  
Jin Kuk Kim ◽  
Young Rim Song ◽  
...  

2020 ◽  
Vol 18 (6) ◽  
pp. 43-48
Author(s):  
R. I. GABIDULLINA ◽  
◽  
E. I. GALIMYANOVA ◽  
V. I. EREMKINA ◽  
A. M. SHARAPOVA ◽  
...  

The purpose — to evaluate the effect of combined oral contraceptive containing 17β-estradiol on sexuality, severity of depression and quality of life in women of reproductive age. Material and methods. The study involved 53 women in need of contraception aged 18 to 50 years. For the contraceptive purpose women used COC containing 1,5 mg of 17 β -estradiol (E2) and 2,5 mg of nomegestrol acetate (NOMAC) (E2/NOMAC). The questionnaires used in the study are: Female Sexuality Function Index (FSFI-6), Beck Depression Inventory, SF-36 — for evaluating Health-Related Quality of Life. The survey was conducted before and after six months of E2/NOMAC intake; the correlations between the studied parameters and the level of sex hormones in patient’s blood sample were determined. Results. The intake of E2/NOMAC for 6 months did not have negative effect on Female Sexuality Function Index. At the same time, a statistically significant improvement up to 5 points was revealed in such parameters as sexual satisfaction (p = 0,03) and lubrication (p < 0,001). There was a significant decrease in the frequency and severity of depression measured by the Beck Depression Inventory. The Short Form-36 Health Survey revealed a tendency to improve the physical and mental health components of the quality of life (p> 0,05). The change in total testosterone level had a moderate negative relationship with the change in Female Sexuality Function Index (r = — 0,32; p = 0,02). Conclusion. The intake of combined oral contraceptive containing 17β-estradiol for 6 months was associated with no adverse impact on female sexuality and quality of life in women of reproductive age, and reduced the levels of frequency and severity of depression.


Sign in / Sign up

Export Citation Format

Share Document