FP12.03 Associations of Urinary Biomarkers of Tobacco Toxicants With Lung Cancer Incidence in Smokers: The Multiethnic Cohort Study

2021 ◽  
Vol 16 (10) ◽  
pp. S965
Author(s):  
S. Cigan ◽  
S. Murphy ◽  
Y. Patel ◽  
D. Stram ◽  
L. Le Marchand ◽  
...  
PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0178435 ◽  
Author(s):  
Sungshim L. Park ◽  
Sharon E. Murphy ◽  
Lynne R. Wilkens ◽  
Daniel O. Stram ◽  
Stephen S. Hecht ◽  
...  

2007 ◽  
Vol 12 (4) ◽  
pp. 178-182 ◽  
Author(s):  
Yoneatsu Osaki ◽  
Mikizo Okamoto ◽  
Akihiko Kaetsu ◽  
Takuji Kishimoto ◽  
Akihiko Suyama

Thorax ◽  
2020 ◽  
Vol 75 (6) ◽  
pp. 506-509 ◽  
Author(s):  
Hye Yun Park ◽  
Danbee Kang ◽  
Sun Hye Shin ◽  
Kwang-Ha Yoo ◽  
Chin Kook Rhee ◽  
...  

There has been limited evidence for the association between chronic obstructive pulmonary disease (COPD) and the incidence of lung cancer among never smokers. We aimed to estimate the risk of lung cancer incidence in never smokers with COPD, and to compare it with the risk associated with smoking. This cohort study involved 338 548 subjects, 40 to 84 years of age with no history of lung cancer at baseline, enrolled in the National Health Insurance Service National Sample Cohort. During 2 355 005 person-years of follow-up (median follow-up 7.0 years), 1834 participants developed lung cancer. Compared with never smokers without COPD, the fully-adjusted hazard ratios (95% CI) for lung cancer in never smokers with COPD, ever smokers without COPD, and ever smokers with COPD were 2.67 (2.09 to 3.40), 1.97 (1.75 to 2.21), and 6.19 (5.04 to 7.61), respectively. In this large national cohort study, COPD was also a strong independent risk factor for lung cancer incidence in never smokers, implying that COPD patients are at high risk of lung cancer, irrespective of smoking status.


The Lancet ◽  
2015 ◽  
Vol 386 ◽  
pp. S5 ◽  
Author(s):  
Yuming Guo ◽  
Hongmei Zeng ◽  
Rongshou Zheng ◽  
Shanshan Li ◽  
Adrian G Barnett ◽  
...  

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