Contemporary results with the biosynthetic glutaraldehyde denatured ovine collagen graft (Omniflow II) in femoropopliteal position

Background: Frey’s syndrome is a well-known complication of parotid surgery; its prevention may be achieved by the use of an interpositional barrier between the overlying flaps and the exposed parenchymal bed of parotid gland. The aim of this study was to retrospectively evaluate clinical outcomes with and without the interpositional placement of a porcine dermal collagen graft (PDCG) for prevention of syndrome occurrence. Methods: We conducted a 20-year retrospective study including the patients who had undergone “formal” (superficial, total, or subtotal) parotidectomies for benign pathologies. The inclusion criteria also involved patients that were (i) regularly monitored about clinical symptoms related to syndrome, and (ii) examined with Minor starch-iodine test. The severity of the diagnosed syndrome was retrospectively evaluated according to the grading score system of Luna-Ortiz. To assess group differences in terms of the extent of dissection in operating sites, we estimated the tumor and histological specimen volumes using the available dimensions. Results: We included 73 patients who had undergone 76 formal parotid surgeries. The surgical sites were divided into 2 groups: (1) Group A consisted of 44 sites that were reconstructed with a SMAS flap, and (2) Group B, comprised 32 sites where a PDCG was additionally applied as an artificial preventive barrier. At a mean follow-up of 26.3 months, a significantly lower incidence of clinically diagnosed Frey’s syndrome was found after the use of dermal collagen interpositional barrier ( P = .031). Specifically, subjective symptoms were reported at an incidence of 31.8% in Group A and 6.7% in Group B. Minor’s test was positive at an incidence of 59.09% in Group A and 21.87% in Group B ( P = .004, 95% CI). Severe Frey’s syndrome was observed in 31.82% of the patients of Group A and in 3.12% of the patients of Group B ( P = .002, 95% CI). Since there were no statistical significant differences between the volumes of the removed tumors and the excised histological specimens, the extent of dissection was not proved to influence the occurrence of Frey’s syndrome in the compared groups, Conclusion: Porcine dermal collagen is a safe, practical, and useful means for parotid reconstruction, since it seems to contribute in prevention of Frey’s syndrome when increased amount of glandular tissue has to be removed. Additional randomized controlled studies with bigger samples are required to better assess the PDCG use in parotid surgery.

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Omniflow II biosynthetic grafts versus expanded polytetrafluoroethylene grafts for infrainguinal bypass surgery. A single-center retrospective analysis

Vascular ◽

10.1177/17085381211029815 ◽

2021 ◽

pp. 170853812110298

Author(s):

Bart CT van de Laar ◽

Hugo C van Heusden ◽

Pieternel CM Pasker-de Jong ◽

Vincent van Weel

Keyword(s):

Limb Salvage ◽

Infection Rate ◽

Bypass Surgery ◽

Primary Patency ◽

Knee Surgery ◽

Secondary Patency ◽

Single Center ◽

Expanded Polytetrafluoroethylene ◽

Infrainguinal Bypass ◽

Omniflow Ii

Introduction: The aim of this study is to evaluate the outcome of Omniflow II biosynthetic vascular grafts as compared to synthetic expanded polytetrafluoroethylene (ePTFE) grafts in infrainguinal bypass surgery. Methods: A single-center, retrospective, observational study was performed reviewing patients with critical limb ischemia who underwent infrainguinal bypass surgery between 2014 and 2018. Patients characteristics, graft characteristics, and treatment outcomes were collected. Patency rates were compared using Kaplan–Meier estimates. Results: Sixty bypasses were performed in 57 patients. For above-knee surgery, six were Omniflow and 13 were synthetic. For below-knee surgery, 19 were Omniflow and 22 were synthetic. Patient characteristics between groups were similar. However, American Society of Anesthesiologists (ASA) classification scores were higher in the Omniflow group as compared to ePTFE (88% was ASA 3 or higher versus 60%; p = 0.018). Furthermore, wound, ischemia, and foot infection (WIfI) composite scores were higher in the Omniflow group ( p = 0.0001). There was a trend toward more active infection at time of surgery in the Omniflow group (40 vs 22.9%, p = 0.15). At 1 year, primary patency rates were 60.0% versus 46.9% for above-knee Omniflow versus ePTFE grafts, respectively ( p = 0.72). Secondary patency rates were 80.0% versus 82.5% ( p = 0.89), and limb salvage rates were 83.3% versus 100% ( p = 0.14). For below-knee surgery, 1- and 2-year primary patency rates in Omniflow versus ePTFE grafts were 36.0% versus 41.8% ( p = 0.60) and 36.0% versus 31.1% ( p = 0.87). Secondary patency rates were 66.8% versus 75.2% at 1 year ( p = 0.53) and 58.8% versus 48.3% ( p = 0.77) at 2 years. Below-knee limb salvage rates for Omniflow versus ePTFE after 2 years were 88.0% versus 68.3% ( p = 0.28), respectively. Aneurysmal degeneration occurred in 2/25 (8%) in the Omniflow group and 0/35 (0%) in the ePTFE group. Bypass infections occurred in 2/25 (8%) in the Omniflow group and 0/35 (0%) in the ePTFE group ( p = 0.09). Conclusion: Omniflow bypasses were more commonly implanted in patients with higher limb infection rate as confirmed with a higher adapted WIfI score. A trend toward a higher infection rate of Omniflow grafts was observed but not statistically significant. Graft infection rates were relatively low and treatable with antibiotics. No significant difference in graft performance was observed. The choice between the two studied grafts remains based on surgeon’s preference.

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The solution to a big hole: dermal collagen graft

Irish Journal of Medical Science (1971 -) ◽

10.1007/bf03170197 ◽

2005 ◽

Vol 174 (S1) ◽

pp. 62-63

Author(s):

K. Ahmad ◽

D. J. Waldron ◽

P. A. Grace

Keyword(s):

Dermal Collagen ◽

Collagen Graft

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Clinical evaluation following the use of mineralized collagen graft for bone defects in revision total hip arthroplasty

Regenerative Biomaterials ◽

10.1093/rb/rbv022 ◽

2015 ◽

Vol 2 (4) ◽

pp. 245-249 ◽

Cited By ~ 12

Author(s):

Cheng Huang ◽

Liwu Qin ◽

Wei Yan ◽

Xisheng Weng ◽

Xiangjie Huang

Keyword(s):

Total Hip Arthroplasty ◽

Clinical Evaluation ◽

Hip Arthroplasty ◽

Bone Defects ◽

Revision Total Hip Arthroplasty ◽

Total Hip ◽

Collagen Graft ◽

Mineralized Collagen

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Ovine Biosynthetic Grafts for Aortoiliac Reconstructions in Nonsterile Operative Fields

The Thoracic and Cardiovascular Surgeon ◽

10.1055/s-0041-1723000 ◽

2021 ◽

Author(s):

Hazem El Beyrouti ◽

Mohammad Bashar Izzat ◽

Angela Kornberger ◽

Nancy Halloum ◽

Kathrin Dohle ◽

...

Keyword(s):

Treatment Group ◽

Vascular Grafts ◽

Graft Infection ◽

Prosthetic Graft ◽

Vascular Graft Infection ◽

Vascular Prostheses ◽

Graft Thrombosis ◽

Life Threatening ◽

Omniflow Ii

Abstract Background Prosthetic vascular grafts placed surgically or via endovascular techniques can be subject to the risk of life-threatening graft infections. The Omniflow II vascular prosthesis is a biosynthetic graft that was reported to have favorable properties in resisting infections. Materials and Methods We retrospectively reviewed our 3 years' experience of using the Omniflow II prostheses for aortoiliac reconstructions in patients considered to carry a substantial risk of subsequent prosthetic graft infections (prevention group) as well as in patients with actively infected prosthetic vascular grafts (treatment group). Results Aorto-bi-iliac (n = 4) and aortobifemoral (n = 12) vascular reconstructions were performed using bifurcated Omniflow II prostheses in nine patients in the prevention group and seven patients in the treatment group. During mean follow-up of 28.6 ± 17.2 months, there was one case of graft infection (6.3%) and graft thrombosis (6.3%) with subsequent successful thrombectomy. Early and late surgical revisions were required in eight (50%) and two (12.6%) patients, respectively. All graft prostheses were patent at last follow-up. Conclusion Using bifurcated Omniflow II vascular prostheses in patients with or at a high risk of vascular graft infection is advisable, and is associated with acceptable reinfection and patency rates.

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AUTOTRANSPLANTASI GIGI-GIGI IMPAKSI INSISIVUS MAKSILA KANAN DISERTAI KISTA DENTIGEROUS DENGAN PENAMBAHAN GRAFT KOLAGEN KARBONAT APATIT

ODONTO Dental Journal ◽

10.30659/odj.5.1.9-17 ◽

2018 ◽

Vol 5 (1) ◽

pp. 9

Author(s):

Indah Wulansari ◽

Maria Goreti Widiastuti ◽

Prihartiningsih Prihartiningsih

Keyword(s):

Alveolar Bone ◽

Dentigerous Cyst ◽

Apical Part ◽

Maxillary Incisor ◽

Carbonate Apatite ◽

Horizontal Position ◽

Surgery Patient ◽

Dentigerous Cysts ◽

Collagen Graft

Background: Autotransplantation is a surgical movement to reposition teeththat have been erupted, partially erupted or not yet erupted from one place to another in the same individual, either on post-extraction sockets or artifcial sockets made by surgery. Dental folicle from impacted teeth may develope dentigerous cysts that will result in destruction of the jaw bone. There are many factors that inﬂuence the success of autotransplantation, one of which is adequate bone support.The purpose of this poster is to present the successful autotransplantation treatment of impacted right maxillary incisor teeth associated with dentigerous cyst and bone support replacement after cyst enucleation using a carbonate apatite collagen graft, GAMACHA®, at RSUP Dr. Sardjito.Case management: A 9-year-old girl, referred to the Oral and MaxillofacialSurgery Department of RSUP Dr. Sardjito with the complaint of right deciduous maxillary incisor persistence. Radiological examination showing persistent of 51 and 52 radices and impaction of teeth 11 and 12 in a horizontal position above radix 53. Also visible radiolucent image with a frm limit around the crown of 11 that supports the image of cyst. This patient performed cyst enucleation under general anesthesia, removal of impacted 11 and 21, followed by an artifcial socket drilling at the alveolar bone that could support all aspects of the root wall although only on the apical part of the tooth root for teeth 11 and 12 placement. Autotransplantation of teeth11 and 12 followed by the application of GAMACHA® and wire fxation, strengthen with acrylic splint.Conclusion: Two years follow up after surgery, patient have no complaintseither from aesthetic or functional and the result of clinical and radiologicalexamination did not found existence of any pathological abnormalities around teeth 11 and 12.

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Which prosthesis is more resistant to vascular graft infection: polytetrafluoroethylene or Omniflow II biosynthetic grafts?

Surgery Today ◽

10.1007/s00595-015-1141-3 ◽

2015 ◽

Vol 46 (3) ◽

pp. 363-370 ◽

Cited By ~ 7

Author(s):

Orhan Bozoglan ◽

Bulent Mese ◽

Erdinc Eroglu ◽

Serdal Elveren ◽

Mustafa Gul ◽

...

Keyword(s):

Vascular Graft ◽

Graft Infection ◽

Vascular Graft Infection ◽

Omniflow Ii

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New technique: AlloDerm® interposition arthroplasty of thumb carpo-metacarpal joint

Journal of Biomedical Engineering and Informatics ◽

10.5430/jbei.v2n2p36 ◽

2015 ◽

Vol 2 (2) ◽

pp. 36

Author(s):

David Miller Wise

Keyword(s):

Clinical Results ◽

Carpal Bone ◽

Joint Stability ◽

Interposition Arthroplasty ◽

Degenerative Arthritis ◽

Dermal Collagen ◽

Excision Arthroplasty ◽

Collagen Graft ◽

Non Surgical Treatment

Excision arthroplasty is an alternative procedure for degenerative arthritis of the trapezium carpal bone that has failed non-surgical treatment. Autologous or heterologous interposition materials are used following excision of the trapezium, but may not prevent first metacarpal-scaphoid joint collapse or subsidence. AlloDerm® is a cadaver-harvested, immunologically inert dermal collagen graft. This report documents the uncomplicated use of AlloDerm® in 13 thumbs of 9 patients who had first carpometacarpal (CMC) joint excision interposition arthroplasty for degenerative arthritis. Joints functioned well after arthroplasty with AlloDerm®. These clinical results compare favorably to results in 6 Silicon implant CMC arthroplasty patients, and 3 autologous dermal graft CMC arthroplasty patients. Future clinical research, on joint stability, the durability of this collagen graft, newer dermal collagen substrates, and prevention of metacarpal subsidence, will determine the ultimate role of AlloDerm® in interposition arthroplasty.

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