Residual volume fraction during walking using wireless air plethysmography in patients with chronic deep venous disease

Author(s):  
Oscar Maleti ◽  
Andrew Nicolaides ◽  
Sara Guerzoni ◽  
Giorgio Bergamo ◽  
Marzia Lugli
2018 ◽  
Vol 23 (2) ◽  
pp. 139-142
Author(s):  
Kotaro Suehiro ◽  
Noriyasu Morikage ◽  
Koshiro Ueda ◽  
Makoto Samura ◽  
Yuriko Takeuchi ◽  
...  

This study was conducted to identify specific abnormalities using the results from air plethysmography in legs with lymphedema. A routine air plethysmography exercise protocol was performed in 31 patients with unilateral leg lymphedema, and the results were compared with those of 53 patients with unilateral great saphenous vein reflux and 15 normal subjects. The venous filling index in legs with lymphedema (2.1 ± 1.2 mL/sec) was smaller than in legs with great saphenous vein reflux (6.4 ± 4.1 mL/sec, p < 0.05), but was not different from that in normal legs (1.9 ± 1.2 mL/sec). The ejection fraction was similar in all groups. The residual volume fraction in legs with lymphedema (35 ± 32%) was larger than that in normal subjects (13 ± 23%, p < 0.05), but was not significantly different from that in the contralateral leg of the lymphedema patients (32 ± 27%). In conclusion, we found no specific air plethysmography findings in uncomplicated lymphedema.


2008 ◽  
Vol 23 (3) ◽  
pp. 120-124 ◽  
Author(s):  
G Cavalheri ◽  
J M P de Godoy ◽  
C E Q Belczak

Objectives To correlate venous haemodynamic parameters of lower limbs and amplitude of ankle mobility with the clinical, aetiological, anatomical and pathological classification (CEAP) for venous disease. Methods Two hundred and eighty-four lower limbs of 142 Caucasian women were evaluated and distributed in six groups according to the CEAP classification: Group I = C0 and C1 ( n = 24); Group II = C2 ( n = 30); Group III = C3 ( n = 27); Group IV = C4 ( n = 23); Group V = C5 ( n = 20) and Group VI = C6 ( n = 18). Goniometric examinations of ankle joints and air plethysmography (APG) were performed. Analysis of variance and the Bonferroni correction, Kruskal-Wallis' non-parametric and Dunn tests were utilized for statistical analysis with the level of significance being set at 5% ( P value < 0.05). Results There were significant restrictions in ankle mobility seen by goniometry at the C5 stage. In addition, significant changes in the venous-filling index were identified at C2, changes in the ejection fraction at C4 and changes in the residual volume fraction at the C4 stage. Conclusion The evolution of the clinical state of ankles affected by venous diseases is correlated to a reduction of joint mobility and haemodynamic alterations identified using APG.


2019 ◽  
Vol 7 (3) ◽  
pp. 428-440 ◽  
Author(s):  
Seshadri Raju ◽  
Jordan Knepper ◽  
Corbin May ◽  
Alexander Knight ◽  
Nicholas Pace ◽  
...  

2019 ◽  
Vol 4 (2) ◽  
Author(s):  
Taimur Saleem ◽  
Seshadri Raju

Peripheral venous pressure is regulated by central and peripheral mechanisms. Peripheral venous hypertension is an important pathologic component of chronic venous disease and is present in about two-third of patients with chronic venous disease. It can result from reflux, obstructive lesions or high arterial inflow. The dominant influence in patients with peripheral venous hypertension appears to be obstruction rather than reflux. Reflux can be superficial or deep or both. In about 70% of patients with reflux, valvular incompetence is present in the superficial, deep and perforator systems in some combination. In an ex vivo experimental model, conduit pressure increased with smaller native or functional caliber, focal stenosis and increased post-capillary inflow. Venous pressure in the lower limb can be measured in a variety of ways: supine resting pressure, erect resting pressure and ambulatory venous pressure. These measurements are affected by factors such as intra-abdominal pressure, intra-thoracic pressure, gravity, venoarteriolar reflux, valve reflux and venous obstruction. Venous obstruction is associated with elevated supine pressures while reflux is associated with elevated erect resting and ambulatory venous pressures. Ambulatory venous pressure reflects venous hypertension in patients with advanced venous disease. However, our investigation has shown that ambulatory venous pressure hypertension is rarely present if air plethysmography testing is negative. Consideration maybe given to the omission of the ambulatory venous pressure testing if air plethysmography testing is normal.


2013 ◽  
Vol 28 (2) ◽  
pp. 101-108 ◽  
Author(s):  
C R Lattimer ◽  
E Kalodiki ◽  
M Azzam ◽  
G Geroulakos

Objectives It has been suggested that quantification of haemodynamic parameters of venous disease may complement clinical assessment and may help identify a group of patients with severe venous disease or alternatively patients with early venous disease. However, there has been very little work to prove this hypothesis. The venous filling index (VFI) of air-plethysmography (APG) can quantify severity and treatment effect but has limited discriminatory value. However, the components of the VFI, total venous volume (VV) and time to reach 90% of VV (VFT90), have never been fully studied. The aim was to investigate the contribution of VV and VFT90 to an elevated VFI and determine their relationship to great saphenous vein (GSV) diameter and clinical severity scoring. Method Ninety-three consecutive patients/legs (22–78 years) with primary GSV reflux (>0.5 seconds) awaiting endovenous treatment were recruited. CEAP (clinical, aetiological, anatomical and pathological elements) assessments were: 33 (35.5%) C2, 14 (15.0%) C3, 29 (31.2%) C4a, 5 (5.4%) C4b, 7 (7.5%) C5 and 5 (5.4%) C6. The median venous clinical severity score (VCSS) was 6 (2–20) and the averaged GSV diameter at three sites was 7.5 mm (4–12). The VFI, VV and VFT90 were recorded using APG. Results There was no correlation between the VV and the VFT90 ( r = −0.103, P = 0.324). The VFI, VV and VFT90 significantly correlated ( P < 0.0005, Spearman) with the GSV diameter: r = 0.623, r = 0.567, r = −0.432, respectively, and the C of CEAP ( P < 0.05): r = 0.4, r = 0.225, r = −0.343, respectively. None of the 25 (26.9%) patients with a VFT90 > 25 seconds were among the 17 (18.3%) patients in categories C4b–6 or with a VCSS > 9 ( P = 0.005, Fisher's exact test, corrected odds ratio: 17.3). Conclusions The VFT90 complements the VFI as a marker of severe superficial venous insufficiency. However, in contrast to the VFI, it may have discriminatory value in stratifying patients with early disease into two groups based on the severity of haemodynamic impairment.


1999 ◽  
Vol 14 (4) ◽  
pp. 146-150
Author(s):  
P. Zamboni ◽  
D. Quaglio ◽  
C. Cisno ◽  
F. Marchetti ◽  
L. Cisno ◽  
...  

Objective: To study the relationship between two non-invasive methods for determining ambulatory venous pressure (AVP) in primary chronic venous insufficiency of the lower limbs. Design: Comparison between ultrasonic AVP (US-AVP) and residual volume fraction (RVF) determined by means of air plethysmography (APG). Setting: Department of Surgery and Vascular Laboratory, University of Ferrara, Italy. Patients: Twenty-one subjects affected by primary chronic venous insufficiency (CVI). Main outcome measure: A comparison of the AVP values extrapolated from the change in ultrasonic diameter of the saphenous vein after exercise and from RVF values. Ultrasonographic extrapolation was also made by the means of the software Venometer and compared with manual assessment. Results: Linear regression analysis demonstrated that US-AVP values were significantly correlated with RVF values ( r = 0.86 and p<0.0001). Assessment by Venometer as compared with manual calculation showed a high degree of correlation ( r = 0.98), p<0.0001). Conclusions: The two methods for non-invasive assessment of AVP appear to be closely and significantly correlated. The Venometer allows reliable and rapid extrapolation of AVP values.


2015 ◽  
Vol 31 (2) ◽  
pp. 133-140 ◽  
Author(s):  
K Suehiro ◽  
N Morikage ◽  
M Murakami ◽  
O Yamashita ◽  
T Harada ◽  
...  

Objectives To study the differences in impact on venous hemodynamics between larger size strong graduated elastic compression stockings (GECS) and appropriate size strong/moderate GECS. Method In healthy legs fitted for a small (Group S; n = 8) and large (Group L; n = 8) GECS, air plethysmography was performed without GECS, with an appropriate size strong GECS (GECS1), with a three-size too large strong GECS (GECS2), and with an appropriate size moderate GECS (GECS3) in this order. Results In Group S, interface pressure with GECS2 was equal to or higher than that with GECS3. Decreased venous volume, unchanged ejection volume, and decreased residual volume were achieved by GECS, but differences in these parameters among GECS were not observed. Although insignificant, a similar tendency was found in Group L. Conclusions A larger size strong GECS seemed to have equivalent interface pressure and impact on venous hemodynamics compared to an appropriate size moderate or strong GECS.


1999 ◽  
Vol 14 (4) ◽  
pp. 146-150
Author(s):  
P. Zamboni ◽  
D. Quaglio ◽  
C. Cisno ◽  
F. Marchetti ◽  
L. Cisno ◽  
...  

1987 ◽  
Vol 62 (4) ◽  
pp. 1480-1487 ◽  
Author(s):  
R. R. Mercer ◽  
J. M. Laco ◽  
J. D. Crapo

To determine alveolar pressure-volume relationships, alveolar three-dimensional reconstructions were prepared from lungs fixed by vascular perfusion at various points on the pressure-volume curve. Lungs from male Sprague-Dawley rats were fixed by perfusion through the pulmonary artery following a pressure-volume maneuver to the desired pressure point on either the inflation or deflation curve. Tissue samples from lungs were serially sectioned for determination of the volume fraction of alveoli and alveolar ducts and reconstruction of alveoli. Alveoli from lungs fixed at 5 cmH2O on the deflation curve (approximating functional residual volume) had a volume of 173 X 10(3) microns3, a surface area of 11,529 microns2, a mouth opening diameter of 72.7 microns, and a mean caliper diameter of 91.8 micron (SE). Alveolar shape changes during deflation from total lung capacity to residual volume was first (30 to 10 cmH2O) associated with little change in the diameter of the alveoli (102.7 +/- 2.4 to 100.3 +/- 3.3 microns). In the range overlapping normal breathing (10 to 0 cmH2O) there was a substantial decrease in diameter (100.3 +/- 3.3 to 43.3 +/- 2.3 microns). These measurements and others made on the relative changes in the dimensions of the alveolus suggest that the elastic network, particularly around the alveolar ducts, are predominant in determining lung behavior near the volume expansion limits of the lung while the elastic and surface tension properties of the alveoli are predominant in the volume range around functional residual capacity.


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