Postmortem serotonin levels in cerebrospinal and pericardial fluids with regard to the cause of death in medicolegal autopsy

Objective: The aim of this study is to determine the histopathological examination of medicolegal autopsy cases and its correlation with causes of death. Study Design: Retrospective/observational Place and Duration: This study was conducted at department of Pathology, Khairpur Medical College Khairpur Mir's for duration of eight months from 15thMay, 2020 to 15thJanuary, 2021. Methods: Hundred cases of both genders were presented in this study. Cases were aged between 15-75 years. Cases detailed demographics age, sex and body mass index were calculated after taking informed written consent from authorities. Autopsy laboratory was used to take medicolegal autopsies of enrolled cases. 10% formalin solution was used for histopathological examination of all the specimens. In the course of the post-mortem investigation we examined the histopathology results for five major organs, such as the brain, heart, lung, liver and kidneys and compared them with gross anatomical results. Complete data was analyzed by SPSS 24.0 version. Results: 62 (62%) cases were males and 38 (38%) patients were females. Mean age of the participants were 30.52±13.17 years with mean BMI 24.52±16.21kg/m2. Most of the participants 40 (40%) were aged between 25-35 years of age followed by 27 (27%) were aged between 36-45 years. Most of the participants 70 (70%) were from urban area and the rest were 30 (30%) from rural area. Instant death was the most common cause found in 35 (35%) cases, followed by traffic accidents 24 (24%) cases. Most frequent effected organs were lung 29%, heart 26%, liver 21% and brain 18%. In lungs pneumonia was the most common effected pathology among 20 (68.97%) and in heart atherosclerosis was the most common effected pathology among 21 (80.77%). Conclusion: In medicolegal autopsy cases, histopathological analysis may be regarded as a useful method. The most common organ in these cases were the heart, liver and lungs. In certain cases, the histopathological exam of these bodies has been useful in identifying the cause of death. Often pathological results included pneumonia, atherosclerosis and congestion. Keywords: Histopathology, Medicolegal, Cause of death, Autopsy

Download Full-text

Postmortem serum erythropoietin levels in establishing the cause of death and survival time at medicolegal autopsy

International Journal of Legal Medicine ◽

10.1007/s00414-008-0276-9 ◽

2008 ◽

Vol 122 (6) ◽

pp. 481-487 ◽

Cited By ~ 18

Author(s):

L. Quan ◽

B.-L. Zhu ◽

T. Ishikawa ◽

T. Michiue ◽

D. Zhao ◽

...

Keyword(s):

Survival Time ◽

Cause Of Death ◽

Medicolegal Autopsy ◽

Serum Erythropoietin

Download Full-text

Postmortem catecholamine levels in pericardial and cerebrospinal fluids with regard to the cause of death in medicolegal autopsy

Forensic Science International ◽

10.1016/j.forsciint.2013.02.008 ◽

2013 ◽

Vol 228 (1-3) ◽

pp. 52-60 ◽

Cited By ~ 29

Author(s):

Takaki Ishikawa ◽

Li Quan ◽

Tomomi Michiue ◽

Osamu Kawamoto ◽

Qi Wang ◽

...

Keyword(s):

Cause Of Death ◽

Medicolegal Autopsy ◽

Catecholamine Levels

Download Full-text

Evaluation of postmortem S100B levels in the cerebrospinal fluid with regard to the cause of death in medicolegal autopsy

Legal Medicine ◽

10.1016/j.legalmed.2009.02.042 ◽

2009 ◽

Vol 11 ◽

pp. S273-S275 ◽

Cited By ~ 15

Author(s):

Dong-Ri Li ◽

Tomomi Michiue ◽

Bao-Li Zhu ◽

Takaki Ishikawa ◽

Li Quan ◽

...

Keyword(s):

Cerebrospinal Fluid ◽

Cause Of Death ◽

Medicolegal Autopsy

Download Full-text

Quantitative RT-PCR assays of hypoxia-inducible factor‐1α, erythropoietin and vascular endothelial growth factor mRNA transcripts in the kidneys with regard to the cause of death in medicolegal autopsy

Legal Medicine ◽

10.1016/j.legalmed.2006.05.004 ◽

2006 ◽

Vol 8 (5) ◽

pp. 258-263 ◽

Cited By ~ 26

Author(s):

Dong Zhao ◽

Bao-Li Zhu ◽

Takaki Ishikawa ◽

Dong-Ri Li ◽

Tomomi Michiue ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Cause Of Death ◽

Hypoxia Inducible Factor ◽

Vascular Endothelial ◽

Rt Pcr ◽

Mrna Transcripts ◽

Medicolegal Autopsy ◽

Pcr Assays ◽

Endothelial Growth Factor

Download Full-text

Comparison Between Predicted Cause of Death and Cause of Death Found at Autopsy in Medicolegal Autopsy Material

Zeitschrift für Rechtsmedizin ◽

10.1007/bf02116318 ◽

1980 ◽

Vol 85 (3) ◽

pp. 181-187 ◽

Cited By ~ 2

Author(s):

B. Gerdin ◽

O. Lindquist

Keyword(s):

Cause Of Death ◽

Autopsy Material ◽

Medicolegal Autopsy

Download Full-text

PROFIL KASUS AUTOPSI PADA ANAK DI PROVINSI RIAU PERIODE TAHUN 2010-2014

Majalah Kedokteran Andalas ◽

10.22338/mka.v38.i4.p201-207.2015 ◽

2016 ◽

Vol 38 (4) ◽

pp. 201

Author(s):

Mohammad Tegar Indrayana ◽

Dedi Afandi ◽

Stella Putri Wanda ◽

Popi Novia ◽

Satrio Mandala Tinardy

Keyword(s):

Cause Of Death ◽

Health Data ◽

Manner Of Death ◽

Blunt Force ◽

Incised Wound ◽

Unnatural Death ◽

Medicolegal Autopsy ◽

Sharp Force ◽

Death Cases

AbstrakAutopsi pada anak memiliki peranan penting guna mengetahui penyebab kematian tidak wajar pada anak. Penelitian ini bertujuan untuk mengetahui profil kasus autopsi pada anak di Provinsi Riau periode tahun 2010-2014. Data diperoleh dari Visum et Repertum jenazah milik Biddokkes Polda Riau yang dianggap dapat mewakilkan gambaran se-Provinsi Riau. Hasil penelitian didapatkan angka autopsi pada anak di Provinsi Riau periode tahun 2010-2014 berjumlah 15 kasus. Karakteristik korban anak didominasi anak laki-laki (66,7%) berumur 0-5 tahun (46,7%). Didapatkan 5 kasus kekerasan tumpul, 3 kasus kekerasan tajam dan 7 kasus tidak dapat digolongkan jenis kekerasannya. Jenis luka akibat kekerasan tajam didominasi oleh luka sayat (66,7%) dengan lokasi luka tersering di leher (100%) sedangkan jenis luka akibat kekerasan tumpul didominasi oleh luka memar (60%) dengan lokasi luka tersering di kepala (80%). Seluruh kasus merupakan kematian tidak wajar dengan kasus terbanyak adalah dugaan pembunuhan (60%). Polsek Kabupaten Kampar merupakan asal polsek tersering (40%).AbstractAutopsy is an important procedure to detecting cause of death in child unnatural death cases. This study aims to describe the profile of child autopsy in Riau Province, Indonesia 2010-2014. Data was obtained from medicolegal autopsy reports that belongs to Riau Regional Police on Medicine and Health. Data is assumed could covered Riau Province child autopsy insidences. There were 15 child medicolegal autopsies recorded between 2010 and 2014 with boy (66,7%) aged 0 to 5 years old (46,7%) were dominant victims. Of the 15 child medicolegal autopsies, 5 cases were blunt force violence, 3 cases were sharp force violence, and 7 were uncategorized. Incised wound (66,7%) was lead type of wounds on sharp force violence which localized on neck (100%). Contusions (60%) was lead type of wounds on blunt force violence which often localized on head (80%). Our study highlights that homicide was the predominant manner of death (60%) and found that Kampar Regency was frequently requested for medicolegal autopsies reports.

Download Full-text

Accident after accident - unusual death of a patient in hospital

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh0308333n ◽

2003 ◽

Vol 131 (7-8) ◽

pp. 333-336

Author(s):

Slobodan Nikolic ◽

Jelena Micic ◽

Slobodan Savic

Keyword(s):

Cause Of Death ◽

Medical Staff ◽

Traffic Accident ◽

Brain Infarction ◽

Medical Documentation ◽

Terminal Phase ◽

Multiple Fractures ◽

Easy Task ◽

Medicolegal Autopsy

The authors present a case of accidental fatal laryngopharyngeal obstruction with bolus of food, in hospital, in a patient who has been treated for twenty days because of injuries sustained in a traffic accident. The injuries were multiple fractures and brain contusions that were not clinically diagnosed, while their simptomatology (somnolence) was attributed to morbous lesions - multifocal brain infarction. Mechanical asphyxiation and death occurred when the patient was fed in hospital by his brother. Unofficially we got an information that whole event was very dramatical, and that medical staff tried to attempt re-suscitative measures but without any written note about that in medical documentation. The terminal phase of his chronic desompensated cardiomyopathia was clinically announced as a cause of death. For forensic pathologists it was relatively easy task to prove mechanical asphyxiation due to laringopharyngeal blockage as a real cause of death on medicolegal autopsy.

Download Full-text