Medicolegal Autopsy: Histopathological Examination of Medicolegal Autopsy Cases and Its Correlation with Causes of Death

2021 ◽  
Vol 15 (5) ◽  
pp. 1495-1497
Author(s):  
S. S. A. Naqvi ◽  
Gulshad . ◽  
K. Sheikh ◽  
I. Wagan ◽  
A. Maher ◽  
...  

Objective: The aim of this study is to determine the histopathological examination of medicolegal autopsy cases and its correlation with causes of death. Study Design: Retrospective/observational Place and Duration: This study was conducted at department of Pathology, Khairpur Medical College Khairpur Mir's for duration of eight months from 15thMay, 2020 to 15thJanuary, 2021. Methods: Hundred cases of both genders were presented in this study. Cases were aged between 15-75 years. Cases detailed demographics age, sex and body mass index were calculated after taking informed written consent from authorities. Autopsy laboratory was used to take medicolegal autopsies of enrolled cases. 10% formalin solution was used for histopathological examination of all the specimens. In the course of the post-mortem investigation we examined the histopathology results for five major organs, such as the brain, heart, lung, liver and kidneys and compared them with gross anatomical results. Complete data was analyzed by SPSS 24.0 version. Results: 62 (62%) cases were males and 38 (38%) patients were females. Mean age of the participants were 30.52±13.17 years with mean BMI 24.52±16.21kg/m2. Most of the participants 40 (40%) were aged between 25-35 years of age followed by 27 (27%) were aged between 36-45 years. Most of the participants 70 (70%) were from urban area and the rest were 30 (30%) from rural area. Instant death was the most common cause found in 35 (35%) cases, followed by traffic accidents 24 (24%) cases. Most frequent effected organs were lung 29%, heart 26%, liver 21% and brain 18%. In lungs pneumonia was the most common effected pathology among 20 (68.97%) and in heart atherosclerosis was the most common effected pathology among 21 (80.77%). Conclusion: In medicolegal autopsy cases, histopathological analysis may be regarded as a useful method. The most common organ in these cases were the heart, liver and lungs. In certain cases, the histopathological exam of these bodies has been useful in identifying the cause of death. Often pathological results included pneumonia, atherosclerosis and congestion. Keywords: Histopathology, Medicolegal, Cause of death, Autopsy

2015 ◽  
Vol 84 (5) ◽  
Author(s):  
Nursel Türkmen İnanır ◽  
Selçuk Çetin ◽  
Filiz Eren ◽  
Bülent Eren

Introduction:In our study, our aim was to reveal the relationship between subendocardial hemorrhage (SEH)  which can be seen macroscopically immediately beneath the endocardium, and emerge secondary to many conditions from direct cardiac,  head, and abdominal traumas to hyperemia, and its location with cause of death, its diagnostic value (if any), and whether it can be evaluated as a vital finding.Material and Method :285 autopsy cases diagnosed as SEH which were brought to the Group Presidency of Morgue Specialization Department of the State Institute of Forensic Medicine of Bursa  were included in the studyResults: Study population consisted of 229 (80.4 %) male, and 56 (19.6 %) female patients. Thity-one cases of death were related to natural causes, while the most frequently detected pathological causes of death were isolated abdominal traumas (32.9 %), followed by isolated head traumas (31.9 %).  While traffic accidents ranked first (35.1%) among the events leading to death. Among evaluated cases, SEH was mostly located on septum.Discussion: To fully understand the yet inadequately elucidated pathogenic mechanisms  of SEH , it should be accurately defined by histopathological analysis. Even though various causes of death seen  in association with these lesions suggest more than one underlying pathogenic mechanism, because of their nonspecific characteristics, their possible roles as indicators of vitality (if any) should be reinforced  by further studies.


Author(s):  
K. JYOTI PRASAD ◽  
B. VENKATESULU ◽  
M. ABDUL KHALID

Objectives: Death of an individual is a grave loss to the family and community at large. Death may be natural or unnatural. Analysis of unnatural deaths helps in understanding the causes, manner, and modes of deaths, thereby formulate and implement a proper policy to reduce incidence. Methods: This is a retrospective study of autopsies conducted over 3 years (2018–2020) in the mortuary of Sri Venkateshwara Medical College, Tirupati. During this period, 2579 autopsies were performed. Required data were collected from the requisitions of police, inquest reports, case sheets, medicolegal register, and postmortem reports in a preformed pro forma. Results: Out of the 2579 cases, majority were in the age group of 21–30 years (34.62%) followed by 41–50 years (18.06%). Male-to-female ratio was 2.5:1. Majority were Hindus (83.52%) and most of the subjects belonged to the rural areas (62.89%). Majority were married (78.40%). The most common cause of death was road traffic accident (48.04%) followed by poisoning (15.82%). Accidental deaths were the most common manner of death (60.56%) followed by suicides (33.96%). Conclusion: The present study reveals that the most cases were in 21–30 years age group. Males outnumbered females and the subjects were mostly married and were from rural areas. Road traffic accidents were common cause of death in males and poisoning was the common cause of death in females.


2020 ◽  
Vol 48 (8) ◽  
pp. 771-777
Author(s):  
Maria Pekkola ◽  
Minna Tikkanen ◽  
Mikko Loukovaara ◽  
Jouko Lohi ◽  
Jorma Paavonen ◽  
...  

AbstractBackgroundStillbirth often remains unexplained, mostly due to a lack of any postmortem examination or one that is incomplete and misinterpreted.MethodsThis retrospective cohort study was conducted at the Department of Obstetrics and Gynecology, Helsinki University Hospital, Finland, and comprised 214 antepartum singleton stillbirths from 2003 to 2015. Maternal and fetal characteristics and the results of the systematic postmortem examination protocol were collected from medical records. Causes of death were divided into 10 specific categories. Re-evaluation of the postmortem examination results followed.ResultsBased on our systematic protocol, the cause of death was originally defined and reported as such to parents in 133 (62.1%) cases. Re-evaluation of the postmortem examination results revealed the cause of death in an additional 43 (20.1%) cases, with only 23 (10.7%) cases remaining truly unexplained. The most common cause of stillbirth was placental insufficiency in 56 (26.2%) cases. A higher proportion of stillbirths that occurred at ≥39 gestational weeks remained unexplained compared to those that occurred earlier (24.1% vs. 8.6%) (P = 0.02).ConclusionA standardized postmortem examination and a re-evaluation of the results reduced the rate of unexplained stillbirth. Better knowledge of causes of death may have a major impact on the follow-up and outcome of subsequent pregnancies. Also, closer examination and better interpretation of postmortem findings is time-consuming but well worth the effort in order to provide better counseling for the grieving parents.


2016 ◽  
Vol 8 (1) ◽  
pp. 11-12
Author(s):  
K Shoba ◽  
B Harikumar ◽  
P Jayaganesh ◽  
K Srinivasan

ABSTRACT Introduction Making a protocol is a must to overcome the controversy of doing routine histopathological examination of tonsillectomy specimen. Materials and methods Histopathological report of 100 consecutive tonsillectomy specimens that reached the pathology department of Saveetha Medical College was analyzed. Results Histological examination of the 154 pediatric tonsils showed reactive lymphoid hyperplasia in all the patients. One specimen had a small cartilaginous choristoma. In the 46 adult tonsils, there were two lymphoma, one extensive osteocartilaginous choristoma, and one epidermoid cyst of tonsil. Discussion As the histopathological examination in the pediatric group did not reveal any finding, it can be done only in patients with risk factors. The adult group showed two cases of Hodgkins lymphoma, one epidermoid cyst of tonsil and one osteocartilaginous choristoma tonsil. Hence, we suggest to continue the practice of routine histopathological analysis in adults. Conclusion We suggest continuing the practice of routine histopathological examination of all adult tonsillectomy specimens. How to cite this article Shoba K, Harikumar B, Jayaganesh P, Srinivasan K. Routine Histopathological Analysis of Pediatric and Adult Tonsils. Int J Otorhinolaryngol Clin 2016;8(1):11-12.


2015 ◽  
Vol 36 (6Supl2) ◽  
pp. 4251
Author(s):  
Maria Talita Soares Frade ◽  
Lisanka Ângelo Maia ◽  
Rachel Livingstone Felizola Soares Andrade ◽  
Rodrigo Cruz Alves ◽  
Elise Miyuki Yamasaki ◽  
...  

The objective of this study was to describe the clinical, pathological, and immunohistochemistry characteristics of five cases of toxoplasmosis, an infection often associated with distemper in dogs. From January 2000 to December 2012, a retrospective study was performed analyzed dogs with distemper in the semiarid region of Paraíba. We evaluated this sample to focus on individuals who presented with concomitant structures in protozoa characteristics, and performed immunohistochemistry (IHC) tests using polyclonal anti-Toxoplasma gondii antibody. In all cases, the clinical signs were similar including digestive changes, as well as respiratory, neurological, and ocular lesions, suggesting an infection of canine distemper virus. The diagnosis of distemper was confirmed on histopathological analysis depending on the presence of intranuclear and intracytoplasmic eosinophilic inclusion bodies in different tissues. Histopathological examination also revealed the characteristic presence of parasitic cysts T. gondii in the brain in four cases, and in the lung in one case. The brain cysts were associated with multifocal areas of malacia and lung there was alveolar septa thickening due to infiltration of macrophages, lymphocytes, and plasma cells, with moderate proliferation of type II pneumocytes and coalescing multifocal areas of necrosis. These cysts are characterized by round and strongly basophilic structures, measuring approximately 5 to 70 ?m, delimited by thin wall, stained by hematoxylin and eosin, and immunomarked as brown by immunohistochemistry (IHC) using the chromogen DAB. The diagnosis of toxoplasmosis associated with infection by canine distemper virus in the five case studied was based on microscopic findings and confirmed by immunohistochemistry. Toxoplasmosis should be included in the differential diagnosis of dogs with severe progressive systemic signs, especially when respiratory and neurological involvement is suspected.


2019 ◽  
Vol 1 (1) ◽  
pp. 26-29
Author(s):  
Archana Chaurasia ◽  
Sakshi Gupta ◽  
Braj Bhushan Mall ◽  
Poonam Singh

Introduction: Mandibular angle fracture is a very common fracture of the mandible. These account for approximately 30% of all fractures. These fractures are treated by many techniques such as open reduction or maxilla-mandibular fixation. These fractures have high complication rate accounting for 0% to 32% postoperatively. Material and Methods: This study was conducted on 50 patient reported in Institute of dental sciences, Bareilly and Rohilkhand medical college and hospital, Bareilly to evaluate the outcome of mandibular angle fracture in our institute. Result: Out of 50 patients of mandibular angle fracture, 30 were treated surgically, 17 were treated conservatively, and 3 patients were not interested in any kind of treatment. Males are more commonly affected and road traffic accidents was a very common cause of angle fracture.


2020 ◽  
Vol 23 (3) ◽  
pp. 338-347
Author(s):  
Mohammad Jamalian ◽  
◽  
Mohsen Eslamdost ◽  
Ali Rezaee ◽  
Shabanali Alizadeh ◽  
...  

Background and Aim: The deaths caused by traffic accidents are one of the three leading causes of death in Iran. Considering that all deaths from traffic accidents in the forensic organization are undergoing autopsy and also in the treatment centers under oral autopsies, the cause of death is determined, we determined that the cause of reported death from oral autopsy and medical autopsy Compare the law. Methods & Materials: In this descriptive study, patients who were admitted to the forensic medical center during the year 1395 admitted to the Vali-e-Asr Hospital in Arak, were referred. The causes of death in Vali-asr Hospital were evaluated and compared with the outcome of the forensic oral hearing.  Ethical Considerations: This study ethcally approved by the ethics committee of the Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1395.226). Results: In this study, 109 patients (1.33%) died from a total of 8153 patients with traffic accidents referred to Valiasr hospital in Arak. Of these, 68.8% were male and 31.2% were women. The Mean±SD age of the patients died was 44.03±22.43 years. Also, 59.6% of the dead died during the first 24 hours of the accident. The most common cause of death, according to the results of oral autopsy, was “multiple injuries,” accounting for 49.5% of the patients in 45 patients. Conclusion: Abundance of deaths among patients with road traffic accidents and they referred to Valiasr hospital, which was 1.33%. According to the existing standards and considering that the mortality rate in this center is less than 1.5%. It seems that the level of service delivery in this center is favorable.


1970 ◽  
Vol 37 (2) ◽  
pp. 50-51
Author(s):  
Tejendra Chandra Das ◽  
Mostaque Rahim ◽  
Md Nazmul Hoq ◽  
Mosahef Uddin Ahmed ◽  
Sharmin Yasmin ◽  
...  

Suicide is one of the commonest causes of unnatural death in the world. The number of suicide is increasing over the period of time. Our research focused on a number of factors associated with the occurrence of suicide, these includes- age, gender, religion, cause of death, modes of death. A total of 95 cases of suicide were studied in Sir Salimullah Medical College morgue house in the year 2008. The victims were composed of 33 males (34%) & 62 females (66%) and the age group of 21-30 years was the most common, which indicates occurrence of suicide is more common in young females. Of 95 cases, the most common cause of death was due to asphyxia, 88 cases (92%). Other cases include respiratory failure- 3 cases (3%), hemorrhage & shock- 4 cases (5%). In the discrimination of cause of death, we obtained information on victims & witness as well as investigating the scene & post mortem examination of the victim.   DOI: 10.3329/bmj.v37i2.3593 Bangladesh Medical Journal 37(2) 2008 50-51


2015 ◽  
Vol 22 (03) ◽  
pp. 327-332
Author(s):  
Muhammad Mansoor ul Haq ◽  
Ayesha Khalil ◽  
Hafeezullah Shaikh ◽  
Shahid Mahmood ◽  
Kailash Makhijani

Colonoscopy is one of the most important modalities to investigate complaintsrelated to lower gastrointestinal tract. Terminal ileum is an essential part of the completecolonoscopic examination. Objectives: To observe the diagnostic yield of ileoscopy in patientsundergoing colonoscopy. Design: Retrospective and observational study. Period: January 2010to May 2014. Setting: Liaquat National Hospital and Medical College. Patients and methods:Patients undergoing colonoscopy fulfilling inclusion and exclusion criteria were enrolled.Terminal ileum was examined and biopsies taken if abnormality present. Statistical analysiswas done by SPSS- 18. Result: A total of 1296 patients were included, 884 (68.2%) were maleand 412 (31.8%) were female. Age ranged from 15-90 years. The commonest indication wasbleeding per rectum (35.6%).1133(87.4%) patients had normal mucosa and 163 (12.6%) hadabnormal mucosa on ileoscopy. Of these 163 patients, 68 had ulcers, 56 had inflammation, 29had nodular mucosa and 10 had polyp. Histopathological examination showed non-specificinflammation in 139 patients; granulomatous inflammation in 7; reactive lymphoid hyperplasiain 8; 3 had normal result; biopsies were not taken in remaining 6 patients. By using chi-squaretest we found a significant statistical relationship between macroscopic abnormality of terminalileum mucosa and age of patients, weight loss, chronic diarrhoea, and abdominal pain. Onlogistic regression, age group, chronic diarrhoea and weight loss retained strong relationshipwith macroscopic abnormality of terminal ileum mucosa. Conclusions: Though a large numberof patients (12.6%) had abnormal terminal ileum mucosa, histopathological analysis did notshow any significant yield of ileoscopy. Terminal ileal abnormality was more common in youngand middle aged patients and in patients presenting primarily with chronic diarrhoea andweight loss.


2016 ◽  
Vol 12 (2) ◽  
pp. 9-14
Author(s):  
Mushtaq Ahmad ◽  
Md Fashiur Rahman ◽  
Farial Naima Rahman ◽  
Md Afzalur Rahman

Introduction: Post mortem examination is a process which is required to establish the exact cause of death in sudden, suspicious or unnatural cases. It determines the mode, manner and time passed since death. Objective: To explore the knowledge and attitude of 3rd year medical students regarding post mortem examination at the very beginning of their para clinical course study. Materials and Methods: This descriptive cross sectional study was performed at Armed Forces Medical College, Dhaka during the period of July to September 2016. One hundred fifteen 3rd year students were selected by purposive and convenient method and asked to respond anonymously to a 18 item selfadministered, predesigned, pretested multiple choice questionnaire which dealt with their views on autopsy practice, the knowledge procedure, attitude and perception towards post mortem examination. Ethical permission of authority concerned and verbal consent was obtained from every respondent students. Results: In this study, 108(93.91 %) students gave positive answer about the requirement of autopsy in unnatural death cases. A large number of students 57(49.56%) did not know about the types of autopsy, but more than half 67(58.26%) knew about virtual autopsy. Seventy two (62.61%) answered that heart is the organ sent for histopathological examination and majority 71(61.74%) could identify the viscera sent for chemical analysis. But most of them 65(56.52%) had wrong idea about the laboratory for chemical analysis. Also 70(60.87%) thought that formalin is used for preservation of viscera. Majority students 88(76.52%) answered that autopsy is performed to detect the cause of death. Greater part of respondent 98(85.22%) also said postmortem examination is neither harassment to victim’s relatives and nor disrespect to a dead body. Most of the students 113(98.26%) answered that observation of post mortem examination should be part of MBBS course curriculum and all 115(100%) gave positive response about utility of this chapter in their course studies. Forty one (35.65%) came to know about autopsy from medical books, followed by 35(30.44%) from newspaper/ story books. Almost all 113(98.26%) did not watch any autopsy before their admission to medical college. A greater part of students 74(64.35%) did not know whether autopsy cause any disfigurement of dead bodies. In present study 102(88.69%) students showed positive attitude to have post mortem examination of relatives if required. Majority of samples thought post mortem is not required in putrefied body and 93(80.87%) answered that body can be preserved at mortuary cooler after post mortem when required. Conclusion: Post mortem is an integral part of Forensic Medicine course curriculum. Teaching professionals should give more emphasis to make this chapter more interesting to the medical students. Journal of Armed Forces Medical College Bangladesh Vol.12(2) 2016: 9-14


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