Diagnostic work-up of an elderly patient with unilateral head and neck pain. A case report

2013 ◽  
Vol 18 (6) ◽  
pp. 598-601 ◽  
Author(s):  
Willem De Hertogh ◽  
Peter Vaes ◽  
Jan Versijpt
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Neck Pain ◽  
Head And Neck ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

scholarly journals Death of unknown cause? Post-mortem diagnosis of fulminant course of an EBV-associated secondary hemophagocytic lymphohistiocytosis

2021 ◽  
Author(s):  
Josia Fauser ◽  
Stefan Köck ◽  
Eberhard Gunsilius ◽  
Andreas Chott ◽  
Andreas Peer ◽  
...  
Keyword(s):  
Immune Response ◽  
Case Report ◽  
Macrophage Activation ◽  
Post Mortem ◽  
Life Threatening ◽  
Appropriate Therapy ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Secondary Hemophagocytic Lymphohistiocytosis

SummaryHLH is a life-threatening disease, which is characterized by a dysregulated immune response with uncontrolled T cell and macrophage activation. The often fulminant course of the disease needs a fast diagnostic work-up to initiate as soon as possible the appropriate therapy. We present herein the case of a 71-year-old patient with rapidly progressive hyperinflammatory syndrome, which post mortem resulted in the diagnosis of EBV-associated HLH. With this case report, we intend to highlight the relevance of the HScore in the diagnosis of HLH, to create a greater awareness for EBV as a trigger of HLH, and to demonstrate the importance of treating EBV-associated HLH as early as possible.

scholarly journals COVID-19 lung injury as a primer for immune checkpoint inhibitors (ICIs)-related pneumonia in a patient affected by squamous head and neck carcinoma treated with PD-L1 blockade: a case report

2021 ◽  
Vol 9 (2) ◽  
pp. e001870
Author(s):  
Angelo Dipasquale ◽  
Pasquale Persico ◽  
Elena Lorenzi ◽  
Daoud Rahal ◽  
Armando Santoro ◽  
...  
Keyword(s):  
Lung Injury ◽  
Head And Neck ◽  
Checkpoint Inhibitors ◽  
Experimental Therapy ◽  
Common Mechanism ◽  
Nasopharyngeal Swab ◽  
Immune Mediated ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

By the beginning of the global pandemic, SARS-CoV-2 infection has dramatically impacted on oncology daily practice. In the current oncological landscape, where immunotherapy has revolutionized the treatment of several malignancies, distinguishing between COVID-19 and immune-mediated pneumonitis can be hard because of shared clinical, radiological and pathological features. Indeed, their common mechanism of aberrant inflammation could lead to a mutual and amplifying interaction.We describe the case of a 65–year-old patient affected by metastatic squamous head and neck cancer and candidate to an experimental therapy including an anti-PD-L1 agent. COVID-19 ground-glass opacities under resolution were an incidental finding during screening procedures and worsened after starting immunotherapy. The diagnostic work-up was consistent with ICIs-related pneumonia and it is conceivable that lung injury by SARS-CoV-2 has acted as an inflammatory primer for the development of the immune-related adverse event.Patients recovered from COVID-19 starting ICIs could be at greater risk of recall immune-mediated pneumonitis. Nasopharyngeal swab and chest CT scan are recommended before starting immunotherapy. The awareness of the phenomenon could allow an easier interpretation of radiological changes under treatment and a faster diagnostic work-up to resume ICIs. In the presence of clinical benefit, for asymptomatic ICIs-related pneumonia a watchful-waiting approach and immunotherapy prosecution are suggested.

scholarly journals Chikungunya virus and dengue virus coinfection: a case report from Bangladesh

2018 ◽  
Vol 12 (1) ◽  
pp. 42-43
Author(s):  
Muhammad Abdur Rahim ◽  
Shahana Zaman ◽  
Samira Rahat Afroze ◽  
Hasna Fahmima Haque ◽  
Farhana Afroz ◽  
...  
Keyword(s):  
Case Report ◽  
Virus Infection ◽  
Dengue Virus ◽  
Chikungunya Virus ◽  
Dengue Virus Infection ◽  
Emerging Infection ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up ◽  
Body Ache

A case of concurrent chikungunya virus and dengue virus infection is reported here. The patient presented with fever and generalized body ache. Diagnostic work-up revealed chikungunya-dengue co-infection. Dengue is endemic in Bangladesh while chikungunya is a recently emerging infection. As both the viruses are transmitted by a common vector, Aedes spp., such co-infections are likely to increase in coming years.IMC J Med Sci 2018; 12(1): 42-43

scholarly journals Rhino- Orbito- Cerebral- Mucormycosis with Osteomyelitis in a Patient with Diabetes mellitus: A Case Report and Literature Review

2012 ◽  
Vol 2 (2) ◽  
pp. 124-128 ◽  
Author(s):  
Rumana Habib ◽  
Rashedul Islam ◽  
Aminur Rahman ◽  
NB Bhowmik ◽  
Amirul Haque
Keyword(s):  
Case Report ◽  
Fungal Infection ◽  
Acquired Immunodeficiency Syndrome ◽  
Hematologic Malignancies ◽  
Successful Management ◽  
Acquired Immunodeficiency ◽  
Diagnostic Work ◽  
Immunodeficiency Syndrome ◽  
Work Up ◽  
Diagnostic Work Up

Mucormycosis is a form of fulminant invasive fungal infection of the sinonasal tract that often extends to the orbit, brain, palate, and skin. It is caused by members of the order Mucorales, and it is considered to be the most fatal fungal infection known to man. It is most commonly associated with diabetic ketoacidosis, hematologic malignancies, acquired immunodeficiency syndrome acquired immunodeficiency syndrome, see AIDS. , and immunosuppressive therapy. This rare opportunistic infection exists in many forms, the most common of which is rhinocerebral mucormycosis. Treatment includes aggressive surgical debridement of the necrotic tissue combined with systemic antifungal therapy. In this case report, we describe the successful management of rhinoorbitocerebral mucormycosis, a subtype of the rhinocerebral variety, complicated by osteomyelitis of cranium. We review the diagnostic work-up and discuss the literature with respect to the presentation, pathophysiology, management, and outcome of the disease.DOI: http://dx.doi.org/10.3329/birdem.v2i2.12331(Birdem Med J 2012; 2(2):124-127)

scholarly journals Septicaemic Melioidosis Complicated by Septic Arthritis in A Bangladeshi male: A Case Report

2018 ◽  
Vol 29 (2) ◽  
pp. 94-96
Author(s):  
Hasna Fahmima Haque ◽  
Suchismita Debnath ◽  
Samira Rahat Afroze ◽  
Farhana Afroz ◽  
Muhammad Abdur Rahim ◽  
...  
Keyword(s):  
Case Report ◽  
Synovial Fluid ◽  
Septic Arthritis ◽  
Burkholderia Pseudomallei ◽  
Clinical Suspicion ◽  
High Index ◽  
Uncommon Disease ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Melioidosis is an uncommon disease in Bangladesh but in recent years increasing numbers of cases are being diagnosed. A case of septicaemic melioidosis occurring in a young Bangladeshi returning worker is reported here. The patient presented with fever and features of septic arthritis. Diagnostic work-up revealed the growth of Burkholderia pseudomallei from blood and synovial fluid cultures. This case highlights the importance of high index of clinical suspicion for melioidosis in appropriate clinical scenario.Bangladesh J Medicine Jul 2018; 29(2) : 94-96

Steroid cell tumour not otherwise specified during pregnancy: a case report and diagnostic work-up for virilisation in a pregnant patient

2004 ◽  
Vol 112 (2) ◽  
pp. 221-227 ◽  
Author(s):  
Annelie J.E Vulink ◽  
Istvan Vermes ◽  
Philip Kuijper ◽  
Lambert Naudin ten Cate ◽  
Eltjo M.J Schutter
Keyword(s):  
Case Report ◽  
Pregnant Patient ◽  
Cell Tumour ◽  
Not Otherwise Specified ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

scholarly journals Adult-Onset Severe Hypocalcemia Due Defect in Parathyroid Calcium-Sensing Receptors

2020 ◽  
Vol 5 (07) ◽  
pp. 250-251
Author(s):  
Kamel El-Reshaid ◽  
Shaikha Al-Bader
Keyword(s):  
Case Report ◽  
Adult Onset ◽  
Common Cause ◽  
Autoimmune Polyglandular Syndrome ◽  
Calcium Sensing ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Parathyroidectomy, of the 4 glands, with/without thyroidectomy is the most common cause of hypoparathyroidism. Autoimmunity is a rare etiology, either as an isolated endocrinopathy or as a component of autoimmune polyglandular syndrome 1 (APS 1). In this case report; we describe a patient with an adult-onset hypoparathyroidism and discuss its pathophysiology in relation to calcium-sensing receptors in addition to its diagnostic work up and management.

Lipomas of the head and neck: presentation variability and diagnostic work-up

2005 ◽  
Vol 120 (01) ◽  
Author(s):  
Mohamed H Abd El-Monem ◽  
Alaa H Gaafar ◽  
Emad A Magdy
Keyword(s):  
Head And Neck ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up

Predictive factors for simultaneous distant metastasis in head and neck cancer patients during the diagnostic work-up

2021 ◽  
Author(s):  
Carlos Miguel Chiesa-Estomba ◽  
Maria Soriano-Reixach ◽  
Ekhiñe Larruscain-Sarasola ◽  
Jon Alexander Sistiaga-Suarez ◽  
Jose Angel González-García ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Predictive Factors ◽  
Distant Metastasis ◽  
Diagnostic Work ◽  
Work Up ◽  
Diagnostic Work Up
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