Leukemia inhibitory factor prevents chicken follicular atresia through PI3K/AKT and Stat3 signaling pathways

2022 ◽  
pp. 111550
Author(s):  
Juan Dong ◽  
Changquan Guo ◽  
Shuo Zhou ◽  
An Zhao ◽  
Jian Li ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Leukemia Inhibitory Factor ◽  
Inhibitory Factor ◽  
Follicular Atresia ◽  
Stat3 Signaling

scholarly journals Requirement of Leukemia Inhibitory Factor or Epidermal Growth Factor for Pre-Implantation Embryogenesis via JAK/STAT3 Signaling Pathways

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0153086 ◽  
Author(s):  
En-Hui Cheng ◽  
Jer-Yuh Liu ◽  
Tsung-Hsein Lee ◽  
Chun-Chia Huang ◽  
Chung-I Chen ◽  
...  
Keyword(s):  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Signaling Pathways ◽  
Leukemia Inhibitory Factor ◽  
Inhibitory Factor ◽  
Stat3 Signaling ◽  
Epidermal Growth

scholarly journals Leukemia inhibitory factor protects photoreceptor cone cells against oxidative damage through activating JAK/STAT3 signaling

2021 ◽  
Vol 9 (2) ◽  
pp. 152-152
Author(s):  
Shuqian Dong ◽  
Fangyuan Zhen ◽  
Huizhuo Xu ◽  
Qiuming Li ◽  
Jiajia Wang
Keyword(s):  
Oxidative Damage ◽  
Leukemia Inhibitory Factor ◽  
Inhibitory Factor ◽  
Stat3 Signaling ◽  
Cone Cells

scholarly journals Gprc5a Deletion Enhances the Transformed Phenotype in Normal and Malignant Lung Epithelial Cells by Eliciting Persistent Stat3 Signaling Induced by Autocrine Leukemia Inhibitory Factor

2010 ◽  
Vol 70 (21) ◽  
pp. 8917-8926 ◽  
Author(s):  
Yulong Chen ◽  
Jiong Deng ◽  
Junya Fujimoto ◽  
Humam Kadara ◽  
Taoyan Men ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Leukemia Inhibitory Factor ◽  
Lung Epithelial Cells ◽  
Inhibitory Factor ◽  
Stat3 Signaling ◽  
Lung Epithelial

scholarly journals Leukemia inhibitory factor enhances mast cell growth in a mast cell/fibroblast co-culture system through Stat3 signaling pathway of fibroblasts

FEBS Letters ◽  
2000 ◽  
Vol 487 (2) ◽  
pp. 219-223 ◽  
Author(s):  
Takaaki Hiragun ◽  
Eishin Morita ◽  
Shoji Mihara ◽  
Toshihiko Tanaka ◽  
Eiichi Gyotoku ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Growth ◽  
Signaling Pathway ◽  
Leukemia Inhibitory Factor ◽  
Culture System ◽  
Inhibitory Factor ◽  
Stat3 Signaling ◽  
Stat3 Signaling Pathway

scholarly journals Uterine Msx-1 and Wnt4 Signaling Becomes Aberrant in Mice with the Loss of Leukemia Inhibitory Factor or Hoxa-10: Evidence for a Novel Cytokine-Homeobox-Wnt Signaling in Implantation

2004 ◽  
Vol 18 (5) ◽  
pp. 1238-1250 ◽  
Author(s):  
Takiko Daikoku ◽  
Haengseok Song ◽  
Yong Guo ◽  
Anne Riesewijk ◽  
Sietse Mosselman ◽  
...  
Keyword(s):  
Wnt Signaling ◽  
Signaling Pathways ◽  
Gene Targeting ◽  
Leukemia Inhibitory Factor ◽  
Homeobox Gene ◽  
Signaling Network ◽  
Mutant Mice ◽  
Inhibitory Factor ◽  
Mouse Uterus ◽  
Reciprocal Interaction

Abstract Successful implantation absolutely depends on the reciprocal interaction between the implantation-competent blastocyst and the receptive uterus. Expression and gene targeting studies have shown that leukemia inhibitory factor (LIF), a cytokine of the IL-6 family, and Hoxa-10, an abdominalB-like homeobox gene, are crucial to implantation and decidualization in mice. Using these mutant mice, we sought to determine the importance of Msx-1 (another homeobox gene formerly known as Hox-7.1) and of Wnt4 (a ligand of the Wnt family) signaling in implantation because of their reported functions during development. We observed that Msx-1, Wnt4, and a Wnt antagonist sFRP4 are differentially expressed in the mouse uterus during the periimplantation period, suggesting their role in implantation. In addition, we observed an aberrant uterine expression of Msx-1 and sFRP4 in Lif mutant mice, and of Wnt4 and sFRP4 in Hoxa-10 mutant mice, further reinforcing the importance of these signaling pathways in implantation. Collectively, the present results provide evidence for a novel cytokine-homeotic-Wnt signaling network in implantation.

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