Leisure-time physical activity and incident metabolic syndrome: a systematic review and dose-response meta-analysis of cohort studies

Metabolism ◽  
2017 ◽  
Vol 75 ◽  
pp. 36-44 ◽  
Author(s):  
Dongdong Zhang ◽  
Xuejiao Liu ◽  
Yu Liu ◽  
Xizhuo Sun ◽  
Bingyuan Wang ◽  
...  
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Metabolic Syndrome ◽  
Cohort Studies ◽  
Dose Response ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Meta Analysis

Associations of leisure-time physical activity with cardiovascular mortality: A systematic review and meta-analysis of 44 prospective cohort studies

2018 ◽  
Vol 25 (17) ◽  
pp. 1864-1872 ◽  
Author(s):  
Wenke Cheng ◽  
Zhen Zhang ◽  
Wensi Cheng ◽  
Chong Yang ◽  
Linlin Diao ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Cohort Studies ◽  
Negative Correlation ◽  
Dose Response ◽  
Cardiovascular Mortality ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Meta Analysis ◽  
Prospective Cohort Studies

Background Many cohort studies within the past few decades have shown the protective effect of leisure-time physical activity on cardiovascular mortality. To summarise the evidence from prospective cohort studies on the relationship between the amount of leisure-time physical activity and the risk of cardiovascular mortality, a dose–response meta-analysis was conducted in this study. Methods and results Electronic databases, including PubMed and Embase databases, Scopus and Cochrane Library, were systemically retrieved by two investigators from inception to 14 June 2018 for related studies. The maximum adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were extracted, and a dose–response analysis was conducted using the restricted cubic splines. Finally, a total of 44 studies comprising 1,584,181 participants was enrolled into this meta-analysis. The HRs of cardiovascular mortality for moderate and high leisure-time physical activity were 0.77 (95% CI 0.74–0.81) and 0.73 (95% CI 0.69–0.77), respectively. Among these 44 studies, 19 were eligible for the dose–response meta-analysis, which suggested a linear negative correlation of leisure-time physical activity with cardiovascular mortality, regardless of age, gender and the presence of underlying cardiovascular disease or not. Conclusions Leisure-time physical activity shows a linear negative correlation with the risk of cardiovascular mortality regardless of age, gender and the presence of cardiovascular disease or not. However, the cardiovascular benefits of leisure-time physical activity is decreased for those aged over 65 years or those with a history of cardiovascular disease. Moreover, leisure-time physical activity displays more cardiovascular benefits to people followed up for over 10 years than to those followed up for less than 10 years. Besides, high-intensity leisure-time physical activity has more obvious cardiovascular benefits than those of moderate-intensity leisure-time physical activity.

Leisure-time physical activity and lung cancer risk: A systematic review and meta-analysis

Lung Cancer ◽  
2016 ◽  
Vol 95 ◽  
pp. 17-27 ◽  
Author(s):  
Darren R. Brenner ◽  
Demetra H. Yannitsos ◽  
Megan S. Farris ◽  
Mattias Johansson ◽  
Christine M. Friedenreich
Keyword(s):  
Physical Activity ◽  
Lung Cancer ◽  
Systematic Review ◽  
Cancer Risk ◽  
Leisure Time ◽  
Lung Cancer Risk ◽  
Leisure Time Physical Activity ◽  
Meta Analysis

scholarly journals Do highly physically active workers die early? A systematic review with meta-analysis of data from 193 696 participants

2018 ◽  
Vol 52 (20) ◽  
pp. 1320-1326 ◽  
Author(s):  
Pieter Coenen ◽  
Maaike A Huysmans ◽  
Andreas Holtermann ◽  
Niklas Krause ◽  
Willem van Mechelen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Health Outcomes ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Meta Analysis ◽  
Occupational Physical Activity ◽  
Low Level ◽  
All Cause Mortality ◽  
High Level

ObjectiveRecent evidence suggests the existence of a physical activity paradox, with beneficial health outcomes associated with leisure time physical activity, but detrimental health outcomes for those engaging in high level occupational physical activity. This is the first quantitative systematic review of evidence regarding the association between occupational physical activity and all-cause mortality.DesignSystematic review with meta-analysis.Data sourceA literature search was performed in electronic databases PubMed, Embase, CINAHL, PsycINFO and Cochrane.Eligibility criteria for selecting studiesWe screened for peer reviewed articles from prospective studies assessing the association of occupational physical activity with all-cause mortality. A meta-analysis assessed the association of high (compared with low) level occupational physical activity with all-cause mortality, estimating pooled hazard ratios (HR) (with 95% CI).Results2490 unique articles were screened and 33 (from 26 studies) were included. Data from 17 studies (with 193 696 participants) were used in a meta-analysis, showing that men with high level occupational physical activity had an 18% increased risk of early mortality compared with those engaging in low level occupational physical activity (HR 1.18, 95% CI 1.05 to 1.34). No such association was observed among women, for whom instead a tendency for an inverse association was found (HR 0.90, 95% CI 0.80 to 1.01).ConclusionsThe results of this review indicate detrimental health consequences associated with high level occupational physical activity in men, even when adjusting for relevant factors (such as leisure time physical activity). These findings suggest that research and physical activity guidelines may differentiate between occupational and leisure time physical activity.

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