scholarly journals Population insulin sensitivity from sparsely sampled oral glucose tolerance tests

Metabolism ◽  
2020 ◽  
Vol 110 ◽  
pp. 154298
Author(s):  
Darko Stefanovski ◽  
Priyathama Vellanki ◽  
Dawn D. Smiley-Byrd ◽  
Guillermo E. Umpierrez ◽  
Raymond C. Boston
Keyword(s):  
Insulin Sensitivity ◽  
Glucose Tolerance ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Oral Glucose Tolerance Tests ◽  
Glucose Tolerance Tests

Low carbohydrate intake and oral glucose-tolerance tests

The Lancet ◽  
1998 ◽  
Vol 352 (9135) ◽  
pp. 1223 ◽  
Author(s):  
Keiji Yoshioka ◽  
Sadayoshi Yokoh ◽  
Toshihide Yoshida
Keyword(s):  
Glucose Tolerance ◽  
Carbohydrate Intake ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Low Carbohydrate ◽  
Oral Glucose Tolerance Tests ◽  
Glucose Tolerance Tests

scholarly journals ogttMetrics: Data structures and algorithms for oral glucose tolerance tests

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 684
Author(s):  
Benjamin J. Stubbs ◽  
Keith Frankston ◽  
Marcel Ramos ◽  
Nancy Laranjo ◽  
Frank M. Sacks ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Open Source Software ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Estimation Of Parameters ◽  
Large Clinical Trial ◽  
Oral Glucose Tolerance Tests ◽  
Open Source Software Package ◽  
Glucose Tolerance Tests ◽  
Data Structures And Algorithms

We describe an open source software package, ogttMetrics, to compute diverse measures of glucose metabolism derived from oral glucose tolerance tests (OGTTs). Tools are provided to organize, visualize and compare OGTT data from large cohorts. Numerical difficulties in estimation of parameters of the Bergman minimal model are described, and in one large clinical trial, the simpler closed form index of Matsuda is observed to lead to similar rankings of individuals with respect to insulin sensitivity, and similar inferences concerning effects of modifications to carbohydrate content and glycemic index of experimental diets.

Reversibility of endocrine changes produced in guinea pigs by exposure to cold

1965 ◽  
Vol 208 (1) ◽  
pp. 115-117 ◽  
Author(s):  
Harry Sobel ◽  
George C. Haberfelde ◽  
Albert E. Reeves
Keyword(s):  
Glucose Tolerance ◽  
Guinea Pigs ◽  
Room Temperature ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Definite Evidence ◽  
Exposure To Cold ◽  
Thyroid Glands ◽  
Oral Glucose Tolerance Tests ◽  
Glucose Tolerance Tests

Guinea pigs were exposed continuously to a temperature of 2–4 C for 6 months. They were then reacclimatized to room temperature, and after 4–6 months certain tests were carried out. During control collections and following exposure to cold the previously cold-exposed animals exhibited urinary corticoid excretion values which were approximately 10% below those of their controls. Following intraperitoneal injection of ACTH the response was approximately 20% greater. However, these differences were not statistically significant. Oral glucose tolerance tests revealed definite evidence of reduction in tolerance in the previously cold-exposed animals. Six animals exhibited 150-min values which exceeded by more than 20 mg/ 100 ml the highest value observed in the controls. Fourteen others whose values fell within this limit exhibited a statistically significant increase in the 150-min value as compared with the controls. The PBI values were the same in each group. There were no histological residues in the pituitary, adrenal, pancreas, and thyroid glands.

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