Multiple assessment methodologies in determining the antibiofilm actions of sodium hypochlorite mixed with clodronate or etidronate in endodontic irrigation

2021 ◽  
Vol 180 ◽  
pp. 106107
Author(s):  
Patricia P. Wright ◽  
Crystal Cooper ◽  
Bill Kahler ◽  
Laurence J. Walsh
Keyword(s):  
Sodium Hypochlorite ◽  
Endodontic Irrigation ◽  
Multiple Assessment

scholarly journals Outcomes of Endodontic Therapy Comparing Conventional Sodium Hypochlorite Irrigation with Passive Ultrasonic Irrigation Using Sodium Hypochlorite and Ethylenediaminetetraacetate. A Retrospective Analysis

2016 ◽  
Vol 10 (1) ◽  
pp. 375-381 ◽  
Author(s):  
Moritz Hertel ◽  
Katja Sommer ◽  
Eckehard Kostka ◽  
Sandra Maria Imiolczyk ◽  
Husam Ballout ◽  
...  
Keyword(s):  
Sodium Hypochlorite ◽  
Clinical Symptoms ◽  
Treatment Success ◽  
Success Rates ◽  
Chi Square ◽  
Passive Ultrasonic Irrigation ◽  
Ultrasonic Irrigation ◽  
Endodontic Irrigation ◽  
Group 2

The aim of the present study was to investigate the clinical outcomes of two different standardized endodontic irrigation protocols. It was assumed that the additional use of ethylenediaminetetraacetate (EDTA) and passive ultrasonic irrigation (PUI) would result in an increased rate of absence of symptoms and remission based on the periapical index (PAI) compared to passive irrigation using only sodium hypochlorite (NaOCl). Data and radiographs from 199 teeth retrieved from the institutional endodontic database were analyzed retrospectively. In 106 teeth irrigation was performed using only NaOCl (protocol 1). Ninety-three teeth were irrigated using NaOCl and EDTA (protocol 2). Chlorhexidine (CHX) was additionally used in revision treatments in both groups. All irrigants in group 2 were activated by PUI. Mean follow-up periods were: protocol 1 = 9.2 ± 4.4 and protocol 2 = 6.6 ± 2.5 months (p < 0.0001 (chi-square test). The frequencies of the PAImasterpoint and PAIfollow-up scores did not differ significantly between teeth, which received either protocol 1 or 2 (p = 0.555 and 0.138). Statistical analysis revealed no significant association between treatment success (absence of clinical symptoms and PAIfollow-up = I or PAImasterpoint > PAIfollow-up > I) and the applied protocol (success rates: protocol 1 = 72.6% vs. protocol 2 = 82.8%; p = 0.203). Furthermore, the frequency of extractions did not differ significantly between the two protocols (p = 0.102). No association was found between follow-up time and treatment success (p = 0.888). The hypothesis was not confirmed. Even though the obtained success rate was higher after supplementing the irrigation protocol with EDTA and PUI, no significance was recorded. Hence, protocol 2 was not superior to protocol 1 regarding therapy success, at least within the limited follow-up period. It may be cautiously concluded that sufficient mechanical debridement combined with passive NaOCl irrigation results in comparably high success rates compared to EDTA and PUI.

scholarly journals Consequences of chemical residue formation during potentiation of final irrigation

2020 ◽  
Vol 19 ◽  
pp. e209594
Author(s):  
Mirela Cesar Barros ◽  
Jessica de Almeida Coelho ◽  
Lidiane de Castro Pinto ◽  
Marco Antônio Húngaro Duarte ◽  
Flaviana Bombarda de Andrade
Keyword(s):  
Sodium Hypochlorite ◽  
Color Change ◽  
Dentinal Tubule ◽  
Control Groups ◽  
Dentinal Tubules ◽  
Color Changes ◽  
Irrigation Methods ◽  
Chemical Residue ◽  
Endodontic Irrigation ◽  
Scanning Electron

Seeking to increase the efficiency of endodontic irrigation, the association of different solutions as final irrigant has been investigated, such as sodium hypochlorite with chlorhexidine. The literature shows that the combination of these substances leads to the formation of a brownish precipitate, but does not reveal measurements of the intensity of this precipitate and its consequences. Aim: The present study aimed to evaluate the change in dentin color and the obliteration of the dentinal tubules after the association of sodium hypochlorite (NaOCl) with chlorhexidine (CHX) in the final irrigation. Methods: Fifty sterile human lower premolars were prepared with a ProDesign R 35.05 files and divided into 6 groups. Four different NaOCl concentrations (0.5%; 1%, 2.5% and 5.25%) associated with 2% CHX were tested, in addition to 2 control groups, using only 2.5% NaOCl and 2% CHX, respectively. After the final irrigation protocol, the dentin color change was evaluated by spectrophotometry immediately and after 24 hours, and the dentinal tubule obliteration was assessed by scanning electron microscopy. Results: It was possible to verify that regardless the NaOCl concentration used when associated with CHX, a chemical residue was formed, with consequent dentin pigmentation and tubular obstruction. There was a trend towards increased dentin pigmentation and tubular obstruction due to the deposition of the chemical residue formed by this association. Conclusion: It can be concluded that all concentrations of NaOCl associated with CHX caused color changes and tubular obstruction, being proportional to the concentration of NaOCl used.

scholarly journals Alexidine versus chlorhexidine for endodontic irrigation with sodium hypochlorite

2018 ◽  
Vol 12 (03) ◽  
pp. 398-402
Author(s):  
Kanav Jain ◽  
Padmanidhi Agarwal ◽  
Supriya Jain ◽  
Mukut Seal ◽  
Twisha Adlakha
Keyword(s):  
Sodium Hypochlorite ◽  
Color Change ◽  
Multiple Time ◽  
Time Intervals ◽  
Dentinal Tubules ◽  
Color Changes ◽  
All Solutions ◽  
Endodontic Irrigation ◽  
Group 2 ◽  
Group 1

ABSTRACT Objective: The objective of this study was to chemically evaluate precipitate formation on irrigation by different concentrations of chlorhexidine (CHX) and alexidine (ALX) with sodium hypochlorite (NaOCl). Materials and Methods: Six test tubes were prepared with 1 ml of 4% NaOCl. One milliliter of 2%, 1%, 0.5%, and 0.25% ALX was added to the first four, and in the last two, 1 ml of 2% CHX and 0.2% CHX was added, respectively. Samples were observed for color changes or precipitates at multiple time intervals. All solutions were then centrifuged at 1000 rpm for 10 min and re-examined for precipitates. This process was repeated twice. Fifty freshly extracted premolars were biomechanically prepared, dried, divided into two groups, and irrigated with 10 ml of 4% NaOCl and 10 ml of 2% ALX (Group 1) and 10 ml of 4% NaOCl and 10 ml of 2% CHX (Group 2). These samples were sectioned and observed for precipitates on the dentinal surfaces by scanning electron microscopy (SEM). Results: The color of the solution of ALX and NaOCl stayed transparent and no precipitate was observed. A color change was noted immediately on mixing CHX and NaOCl which did not change with time. Precipitates were only observed in the solutions of CHX with NaOCl and after centrifuging them. SEM views also showed dense precipitates covering the dentinal surface and occluding the dentinal tubules in Group 2. Conclusion: The interaction of ALX and NaOCl does not produce precipitates which together with its better antimicrobial action make ALX a more effective and safer replacement for CHX as an adjunctive endodontic irrigant.

scholarly journals Radiological Evaluation of Penetration of the Irrigant according to Three Endodontic Irrigation Techniques

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Said Dhaimy ◽  
Sara Imdary ◽  
Sara Dhoum ◽  
Imane Benkiran ◽  
Amal El Ouazzani
Keyword(s):  
Experimental Study ◽  
Stainless Steel ◽  
Penetration Depth ◽  
Sodium Hypochlorite ◽  
Radiological Evaluation ◽  
Canal System ◽  
Significant Difference ◽  
Endodontic Irrigation

Introduction. This experimental study is to compare radiographs based on the penetration depth of the irrigant following three final irrigation techniques.Material and Method. A sample of sixty teeth with single roots were prepared with stainless steel K files followed by mechanized Ni-Ti files iRace® under irrigation with 2.5% sodium hypochlorite. Radiopaque solution was utilized to measure the penetration depth of the irrigant. Three irrigation techniques were performed during this study: (i) passive irrigation, (ii) manually activated irrigation, and (iii) passive irrigation with an endodontic needle CANAL CLEAN®. Radiographs were performed to measure the length of irrigant penetration in each technique.Results. In comparison, passive irrigation with a conventional syringe showed infiltration of the irrigant by an average of0.682±0.105, whereas the manually activated irrigation technique indicated an average of0.876±0.066infiltration. Irrigation with an endodontic syringe showed an average infiltration of0.910±0.043. The results revealed highly significant difference between the three irrigation techniques (α=5%).Conclusion. Adding manual activation to the irrigant improved the result by 20%. This study indicates that passive irrigation with an endodontic needle has proved to be the most effective irrigation technique of the canal system.

Microleakage and Micromorphology of the Resin-dentin Interface in Primary Molars Following Different Endodontic Irrigation Regimens

2007 ◽  
Vol 31 (2) ◽  
pp. 98-103
Author(s):  
Burcu Togay ◽  
Atila Ataç ◽  
Zafer Cehreli
Keyword(s):  
Sodium Hypochlorite ◽  
Microscopic Investigation ◽  
Electron Microscopic Investigation ◽  
Saline Control ◽  
Primary Molars ◽  
Hybrid Zones ◽  
Electron Microscopic ◽  
Root Canals ◽  
Pre Treatment ◽  
Endodontic Irrigation

The aim of this study was to evaluate the effect of two endodontic irrigants (2.5% sodium hypochlorite and 17% Ethylenediamintetraacetic acid) on the microleakage and micromorphology of the resin-dentin interface in pulpectomized primary molars. Standardized Class-II cavities were prepared in extracted, non-carious primary molars after which chemo-mechanical preparation of the root canals were performed in conjunction with K-Files and 2.5% sodium hypochlorite (NaOCl) between each file size. Final irrigation of the specimens were made with either 2.5 NaOCl, 17% Ethylenediamintetraacetic acid (EDTA) or with saline (control). The root canals were filled with a calcium hydroxide paste and the cavities were sub-grouped to be restored with one of the following materials: a:Amalgam, b: Prime&Bond NT (with prior total etch) and TPH resin-based composite, c: Prime&Bond NT and Dyract d: Prime&Bond NT (with Non-Rinse Conditioner pre-treatment); and e:Prompt L-Pop and F2000. Following thermocycling and 90-day water storage, the occlusal and gingival microleakage of restorations were assessed with dye penetration and image analysis. Separate specimens were processed for scanning electron microscopic investigation of the resin-dentin interface. The occlusal and gingival microleakage of the tested restorative systems was not affected by different irrigation regimens (p&gt;0.05), while final restoration with Prime&Bond NT+TPH and Prompt L-Pop+F2000 resulted in the lowest microleakage values (p&lt;0.05). Following the use of 17% EDTA for final flush, the latter two groups produced relatively thicker hybrid zones, when compared to the saline-irrigated specimens.

scholarly journals Evaluation of Apical Vapor Lock Formation and comparative Evaluation of its Elimination using Three different Techniques: An in vitro Study

2017 ◽  
Vol 18 (9) ◽  
pp. 790-794 ◽  
Author(s):  
Anand Agarwal ◽  
Zinnie Nanda ◽  
Rahul B Deore ◽  
Kavitarani Rudagi ◽  
Mirza Osman Baig ◽  
...  
Keyword(s):  
Sodium Hypochlorite ◽  
Root Canal ◽  
Comparative Evaluation ◽  
In Vitro Study ◽  
Apical Region ◽  
Group I ◽  
Working Length ◽  
Significant Difference ◽  
Endodontic Irrigation

ABSTRACT Aim The aim of this study was (i) to evaluate the formation of air bubbles in the apical region of root canal (apical vapor lock) during syringe irrigation, using cone beam computed tomography (CBCT) and (ii) comparative evaluation of the elimination of an established vapor lock by EndoActivator, ultrasonics, and manual dynamic agitation (MDA), using CBCT. Materials and methods A total of 60 extracted human singlerooted teeth were equally divided into three groups of 20 teeth each. The samples were decoronated 17 mm from the apex, cleaned, and shaped to size F4 Protaper using 3% sodium hypochlorite. Samples were irrigated with 3% sodium hypochlorite + cesium chloride radiopaque dye, and preoperative CBCT images were obtained. After formation of apical vapor lock in the scanned teeth, EndoActivator (group I), passive ultrasonic irrigation (group II), and MDA with K-file (group III) were performed and the teeth were again placed in CBCT scanner and results analyzed using the chi-square test. Results The apical vapor lock was formed in all the samples. Out of the 20 teeth in each group, the apical vapor lock was eliminated in 18 samples of EndoActivator group (90%), 16 samples of ultrasonic group (80%), while it was eliminated in 10 samples by MDA (50%). Conclusion It is concluded that (1) apical vapor lock is consistently formed during endodontic irrigation in closed canal systems and (2) sonic activation performs better than the ultrasonics and MDA in eliminating the apical vapor lock, with statistically significant difference between all the three groups (p < 0.05). Clinical significance The results suggest that the apical vapor lock (dead water zone) is consistently formed during endodontic irrigation which impedes irrigant penetration till the working length, thereby leading to inefficient debridement. Hence, to eliminate this vapor lock, techniques, such as sonics or ultrasonics should be used along with the irrigant after shaping and cleaning of the root canal. How to cite this article Agarwal A, Deore RB, Rudagi K, Nanda Z, Baig MO, Fareez MA. Evaluation of Apical Vapor Lock Formation and comparative Evaluation of its Elimination using Three different Techniques: An in vitro Study. J Contemp Dent Pract 2017;18(9):790-794.

Sign in / Sign up

Export Citation Format

Share Document