Comparative analysis of clastogen-induced chromosome aberrations observed with light microscopy and by means of atomic force microscopy

Author(s):  
Vanya Petrova Koleva ◽  
Asya Pencheva Dragoeva ◽  
Andreana Ivanova Andreeva ◽  
Marina Todorova Burova ◽  
Sevdalin Georgiev ◽  
...  
2015 ◽  
Vol 6 ◽  
pp. 1183-1191 ◽  
Author(s):  
Colin A Grant ◽  
Peter C Twigg ◽  
Richard Baker ◽  
Desmond J Tobin

Tattooing has long been practised in various societies all around the world and is becoming increasingly common and widespread in the West. Tattoo ink suspensions unquestionably contain pigments composed of nanoparticles, i.e., particles of sub-100 nm dimensions. It is widely acknowledged that nanoparticles have higher levels of chemical activity than their larger particle equivalents. However, assessment of the toxicity of tattoo inks has been the subject of little research and ink manufacturers are not obliged to disclose the exact composition of their products. This study examines tattoo ink particles in two fundamental skin components at the nanometre level. We use atomic force microscopy and light microscopy to examine cryosections of tattooed skin, exploring the collagen fibril networks in the dermis that contain ink nanoparticles. Further, we culture fibroblasts in diluted tattoo ink to explore both the immediate impact of ink pigment on cell viability and also to observe the interaction between particles and the cells.


Author(s):  
Misato Iwashita ◽  
Tadashi Nomura ◽  
Taeko Suetsugu ◽  
Fumio Matsuzaki ◽  
Satoshi Kojima ◽  
...  

2002 ◽  
Vol 750 ◽  
Author(s):  
Nicole E. Munoz ◽  
Shelley R. Gilliss ◽  
N. Ravishankar ◽  
C. Barry Carter

ABSTRACTVisible-light microscopy (VLM) and atomic-force microscopy (AFM) were used to study the progression of grain-boundary grooving and migration in high-purity alumina (Lucalox™). Groove profiles from the same grain boundaries were revisited using AFM following successive heat-treatments. The grooves measured from migrating grain boundaries were found to have asymmetric partial-angles compared to those measured from boundaries that did not migrate during the experiment. For a moving boundary, the grain with the larger partial-angle was consistently found to grow into the grain with the smaller partial-angle. Migrating boundaries were observed to leave behind remnant thermal grooves. The observations indicate that the boundary may be bowing out during the migration process.


2012 ◽  
Vol 160 (3-4) ◽  
pp. 272
Author(s):  
Tarek Y.S. Kapiel ◽  
Narguess Hossameldin Marei ◽  
Kareem Dorri Zaki ◽  
Ahmed M. Osman ◽  
Eman Galal Zakaria ◽  
...  

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