Track structure based modelling of chromosome aberrations after photon and alpha-particle irradiation

2013 ◽  
Vol 756 (1-2) ◽  
pp. 213-223 ◽  
Author(s):  
Werner Friedland ◽  
Pavel Kundrát
Keyword(s):  
Alpha Particle ◽  
Chromosome Aberrations ◽  
Track Structure ◽  
Particle Irradiation

193. Effect of alpha particle irradiation on coal polished sections

Carbon ◽  
1965 ◽  
Vol 3 (3) ◽  
pp. 382
Author(s):  
E Stach ◽  
J Depireux
Keyword(s):  
Alpha Particle ◽  
Particle Irradiation

Analysis of chromosome aberrations in human peripheral lymphocytes induced by in vitro α-particle irradiation

1996 ◽  
Vol 35 (3) ◽  
pp. 179-184 ◽  
Author(s):  
E. Schmid ◽  
L. Hieber ◽  
U. Heinzmann ◽  
H. Roos ◽  
A. M. Kellerer
Keyword(s):  
Chromosome Aberrations ◽  
Peripheral Lymphocytes ◽  
Particle Irradiation ◽  
Human Peripheral Lymphocytes

Alpha-Particle Irradiation of Ge at 4.2°K

1958 ◽  
Vol 112 (3) ◽  
pp. 732-739 ◽  
Author(s):  
G. W. Gobeli
Keyword(s):  
Alpha Particle ◽  
Particle Irradiation

The recovery of zinc and cadmium following 6.1 MeV alpha particle irradiation at 4.2 K

1978 ◽  
Vol 69-70 ◽  
pp. 700-703 ◽  
Author(s):  
J. Roggen ◽  
J. Nihoul ◽  
J. Cornelis ◽  
L. Stals
Keyword(s):  
Alpha Particle ◽  
Particle Irradiation

Deep level defects and carrier removal due to proton and alpha particle irradiation of InP

1994 ◽  
Vol 75 (6) ◽  
pp. 3187-3189 ◽  
Author(s):  
George C. Rybicki ◽  
Christian A. Zorman
Keyword(s):  
Alpha Particle ◽  
Deep Level ◽  
Particle Irradiation

Cell Survival Following Multiple-track Alpha Particle Irradiation

1979 ◽  
Vol 35 (1) ◽  
pp. 23-31 ◽  
Author(s):  
E.L. Lloyd ◽  
M.A. Gemmell ◽  
C.B. Henning ◽  
D.S. Gemmell ◽  
B.J. Zabransky
Keyword(s):  
Cell Survival ◽  
Alpha Particle ◽  
Particle Irradiation

Low Temperature Alpha Particle Irradiation of a STAR1000 CMOS APS

2008 ◽  
Vol 55 (4) ◽  
pp. 2229-2234 ◽  
Author(s):  
G. R. Hopkinson ◽  
A. Mohammadzadeh
Keyword(s):  
Low Temperature ◽  
Alpha Particle ◽  
Particle Irradiation

scholarly journals Internal microdosimetry of alpha-emitting radionuclides

2019 ◽  
Vol 59 (1) ◽  
pp. 29-62 ◽  
Author(s):  
Werner Hofmann ◽  
Wei Bo Li ◽  
Werner Friedland ◽  
Brian W. Miller ◽  
Balázs Madas ◽  
...  
Keyword(s):  
Alpha Particle ◽  
Specific Energy ◽  
Energy Deposition ◽  
Biological Effects ◽  
Track Length ◽  
Target Cells ◽  
Track Structure ◽  
Level Energy ◽  
Cell Nuclei ◽  
Energy Distributions

AbstractAt the tissue level, energy deposition in cells is determined by the microdistribution of alpha-emitting radionuclides in relation to sensitive target cells. Furthermore, the highly localized energy deposition of alpha particle tracks and the limited range of alpha particles in tissue produce a highly inhomogeneous energy deposition in traversed cell nuclei. Thus, energy deposition in cell nuclei in a given tissue is characterized by the probability of alpha particle hits and, in the case of a hit, by the energy deposited there. In classical microdosimetry, the randomness of energy deposition in cellular sites is described by a stochastic quantity, the specific energy, which approximates the macroscopic dose for a sufficiently large number of energy deposition events. Typical examples of the alpha-emitting radionuclides in internal microdosimetry are radon progeny and plutonium in the lungs, plutonium and americium in bones, and radium in targeted radionuclide therapy. Several microdosimetric approaches have been proposed to relate specific energy distributions to radiobiological effects, such as hit-related concepts, LET and track length-based models, effect-specific interpretations of specific energy distributions, such as the dual radiation action theory or the hit-size effectiveness function, and finally track structure models. Since microdosimetry characterizes only the initial step of energy deposition, microdosimetric concepts are most successful in exposure situations where biological effects are dominated by energy deposition, but not by subsequently operating biological mechanisms. Indeed, the simulation of the combined action of physical and biological factors may eventually require the application of track structure models at the nanometer scale.

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