Milli-, Micro- and Nanofluidics: Manipulating Fluids at Varying Length Scales

2021 ◽  
pp. 100136
Author(s):  
Li Chen ◽  
Chenjing Yang ◽  
Yao Xiao ◽  
Xiaoxiao Yan ◽  
Lingjie Hu ◽  
...  
Keyword(s):  
Length Scales ◽  
Varying Length

Development of the Reattached Flow Behind Surface-Mounted Two-Dimensional Prisms

1988 ◽  
Vol 110 (2) ◽  
pp. 127-133 ◽  
Author(s):  
J. Antoniou ◽  
G. Bergeles
Keyword(s):  
Boundary Layer ◽  
Wind Tunnel ◽  
Open Circuit ◽  
Two Dimensional ◽  
Blow Down ◽  
Length Scales ◽  
Turbulent Eddies ◽  
Flow Parameters ◽  
Varying Length ◽  
Dimensional Surface

Velocity and turbulence measurements are presented for the region after reattachment behind a two dimensional surface-mounted prism of varying length. The prism is mounted on the floor of an open circuit blow down wind tunnel and flow parameters for the developing boundary layer are deduced from the measurements; longitudinal integral time and length scales are estimated through autocorrelations. Reattchment on top of the prism, due to its increased length, affects the characteristics of the developing boundary layer; in this case the shear layer originating from the up-stream edge of the prism splits twice at reattachment points on top and behind the prism and the integral length scales of the turbulent eddies are found to be smaller due to the splitting.

Challenges in Modeling Ground Flares Using Computational Fluid Dynamics

2004 ◽  
Author(s):  
Philip Diwakar ◽  
Vibhor Mehrotra ◽  
Rimon Vallavanatt ◽  
Thomas McLean
Keyword(s):  
Fluid Dynamics ◽  
Computational Fluid Dynamics ◽  
Large Scale ◽  
National Standard ◽  
Complex Nature ◽  
Large Area ◽  
Length Scales ◽  
Flow Problems ◽  
Varying Length ◽  
Wet Ground

Industrial application of Computational Fluid Dynamics (CFD) are varied and many. However CFD requires the solution of complex fluid-flow problems in conjunction with equipment design, process and product development and optimization. The solution of such complex problems is possible through the coordination between industrial CFD engineers, software developers, consultants and academic scientists. In the petrochemical industry, CFD may be used for a variety of purposes such as air recirculation studies in LNG plants, burners in coker furnaces, multiphase studies in heat exchangers to name just a few. In particular combustion, flames, flares and chemical reaction are of interest because of the physics and the complex nature of the process. The topic selected for this presentation is the study of wet ground flares during a large-scale propane release and the effect of the radiation release on the environment and surrounding buildings and vegetation. The flare characteristics and radiation on the surrounding terrain form an integral part of the information required by the National standard for “Control of Major Hazard Facilities”. The study of individual flames from each burner with nozzles of the order of 1mm and the effect of 180 burners in a large area and surrounding terrain with length scales of several hundred meters make up a very intriguing problem of varying length scales. The results of this analysis are presented concentrating on the effects during the large scale conflagration event on the surrounding buildings, vegetation, aircraft, hills and mangroves.

Direct Three-Dimensional Microstructural Characterization and Reconstruction Across Varying Length Scales in α/β Titanium Alloys by Serial Sectioning Using a FEI DualBeam™ (FIB/SEM) and Robo-Met.3D

2008 ◽  
Vol 14 (S2) ◽  
pp. 974-975
Author(s):  
REA Williams ◽  
V Dixit ◽  
P Collins ◽  
HL Fraser
Keyword(s):  
New Mexico ◽  
Titanium Alloys ◽  
Three Dimensional ◽  
Microstructural Characterization ◽  
Serial Sectioning ◽  
Length Scales ◽  
Varying Length

Extended abstract of a paper presented at Microscopy and Microanalysis 2008 in Albuquerque, New Mexico, USA, August 3 – August 7, 2008

scholarly journals Characterization of tissue structure at varying length scales using temporal diffusion spectroscopy

2010 ◽  
Vol 23 (7) ◽  
pp. 745-756 ◽  
Author(s):  
John C. Gore ◽  
Junzhong Xu ◽  
Daniel C. Colvin ◽  
Thomas E. Yankeelov ◽  
Edward C. Parsons ◽  
...  
Keyword(s):  
Tissue Structure ◽  
Length Scales ◽  
Varying Length

An Analytical Thermodynamic Approach to Friction of Rubber on Ice

2012 ◽  
Vol 40 (2) ◽  
pp. 124-150
Author(s):  
Klaus Wiese ◽  
Thiemo M. Kessel ◽  
Reinhard Mundl ◽  
Burkhard Wies
Keyword(s):  
Coefficient Of Friction ◽  
Liquid Layer ◽  
Contact Area ◽  
Leading Edge ◽  
Viscous Friction ◽  
Analytical Approximation ◽  
Real Contact Area ◽  
Length Scales ◽  
Real Contact ◽  
Ice Surface

ABSTRACT The presented investigation is motivated by the need for performance improvement in winter tires, based on the idea of innovative “functional” surfaces. Current tread design features focus on macroscopic length scales. The potential of microscopic surface effects for friction on wintery roads has not been considered extensively yet. We limit our considerations to length scales for which rubber is rough, in contrast to a perfectly smooth ice surface. Therefore we assume that the only source of frictional forces is the viscosity of a sheared intermediate thin liquid layer of melted ice. Rubber hysteresis and adhesion effects are considered to be negligible. The height of the liquid layer is driven by an equilibrium between the heat built up by viscous friction, energy consumption for phase transition between ice and water, and heat flow into the cold underlying ice. In addition, the microscopic “squeeze-out” phenomena of melted water resulting from rubber asperities are also taken into consideration. The size and microscopic real contact area of these asperities are derived from roughness parameters of the free rubber surface using Greenwood-Williamson contact theory and compared with the measured real contact area. The derived one-dimensional differential equation for the height of an averaged liquid layer is solved for stationary sliding by a piecewise analytical approximation. The frictional shear forces are deduced and integrated over the whole macroscopic contact area to result in a global coefficient of friction. The boundary condition at the leading edge of the contact area is prescribed by the height of a “quasi-liquid layer,” which already exists on the “free” ice surface. It turns out that this approach meets the measured coefficient of friction in the laboratory. More precisely, the calculated dependencies of the friction coefficient on ice temperature, sliding speed, and contact pressure are confirmed by measurements of a simple rubber block sample on artificial ice in the laboratory.

Hierarchy of π-Stacking Determines the Conformational Preference of Bis-Squaraines

2020 ◽  
Author(s):  
Abhishek Singh ◽  
Reman K. Singh ◽  
G Naresh Patwari
Keyword(s):  
Hydrogen Bonding ◽  
Rational Design ◽  
Biological Molecules ◽  
Conformational Space ◽  
X Ray Crystallography ◽  
Simple Strategy ◽  
Induced Folding ◽  
Π Stacking ◽  
Varying Length ◽  
Dynamics Simulations

The rational design of conformationally controlled foldable modules can lead to a deeper insight into the conformational space of complex biological molecules where non-covalent interactions such as hydrogen bonding and π-stacking are known to play a pivotal role. Squaramides are known to have excellent hydrogen bonding capabilities and hence, are ideal molecules for designing foldable modules that can mimic the secondary structures of bio-molecules. The π-stacking induced folding of bis-squaraines tethered using aliphatic primary and secondary-diamine linkers of varying length is explored with a simple strategy of invoking small perturbations involving the length linkers and degree of substitution. Solution phase NMR investigations in combination with molecular dynamics simulations suggest that bis-squaraines predominantly exist as extended conformations. Structures elucidated by X-ray crystallography confirmed a variety of folded and extended secondary conformations including hairpin turns and 𝛽-sheets which are determined by the hierarchy of π-stacking relative to N–H···O hydrogen bonds.

Hierarchy of π-Stacking Determines the Conformational Preference of Bis-Squaraines

2020 ◽  
Author(s):  
Abhishek Singh ◽  
Reman K. Singh ◽  
G Naresh Patwari
Keyword(s):  
Hydrogen Bonding ◽  
Rational Design ◽  
Biological Molecules ◽  
Conformational Space ◽  
X Ray Crystallography ◽  
Simple Strategy ◽  
Induced Folding ◽  
Π Stacking ◽  
Varying Length ◽  
Dynamics Simulations

The rational design of conformationally controlled foldable modules can lead to a deeper insight into the conformational space of complex biological molecules where non-covalent interactions such as hydrogen bonding and π-stacking are known to play a pivotal role. Squaramides are known to have excellent hydrogen bonding capabilities and hence, are ideal molecules for designing foldable modules that can mimic the secondary structures of bio-molecules. The π-stacking induced folding of bis-squaraines tethered using aliphatic primary and secondary-diamine linkers of varying length is explored with a simple strategy of invoking small perturbations involving the length linkers and degree of substitution. Solution phase NMR investigations in combination with molecular dynamics simulations suggest that bis-squaraines predominantly exist as extended conformations. Structures elucidated by X-ray crystallography confirmed a variety of folded and extended secondary conformations including hairpin turns and 𝛽-sheets which are determined by the hierarchy of π-stacking relative to N–H···O hydrogen bonds.

Аnticholinesterase and antioxidant activity of new binary conjugates of (с)-carbolines

2019 ◽  
Vol 484 (1) ◽  
pp. 104-108
Author(s):  
G. F. Makhaeva ◽  
E. F. Shevtsova ◽  
N. P. Boltneva ◽  
N. V. Kovaleva ◽  
E. V. Rudakova ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Antioxidant Activity ◽  
Anticholinesterase Activity ◽  
Amyloid Aggregation ◽  
Varying Length ◽  
Β Amyloid ◽  
New Compounds

This study presents the synthesis of binary tetrohydro-γ-carbolines with ditriazol spacers of varying length, which exhibit anticholinesterase and antioxidant activity, as compared to the original Dimebon prototype. Anticholinesterase activity suggests the potential ability of the new compounds to block β-amyloid aggregation induced by anticholinesterase, making them promising candidates for further research preparations for the treatment of Alzheimer's disease. Particular attention should be paid to the conjugate with an intertriazol hexamethylene spacer, which can be regarded as the leading compound in this series.

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