Impaired Face Recognition is Associated with Abnormal Gray Matter Volume in the Posterior Cingulate Cortex in Congenital Amusia

2021 ◽  
pp. 107833
Author(s):  
Zhishuai Jin ◽  
Xuejing Lu ◽  
Sizhu Huyang ◽  
Yajun Yan ◽  
Lichen Jiang ◽  
...  
Keyword(s):  
Face Recognition ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Posterior Cingulate Cortex ◽  
Posterior Cingulate ◽  
Matter Volume ◽  
Congenital Amusia

P1-1-7. Relationship between gray matter volume of posterior cingulate cortex and frontal activation

2018 ◽  
Vol 129 (5) ◽  
pp. e37
Author(s):  
Kazuyuki Fujihara ◽  
Yuichi Takei ◽  
Minami Tagawa ◽  
Kosuke Narita ◽  
Koichi Ujita ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Posterior Cingulate Cortex ◽  
Posterior Cingulate ◽  
Matter Volume

scholarly journals SLC25A24 gene methylation and gray matter volume in females with and without conduct disorder: an exploratory epigenetic neuroimaging study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Elizabeth Farrow ◽  
Andreas G. Chiocchetti ◽  
Jack C. Rogers ◽  
Ruth Pauli ◽  
Nora M. Raschle ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Conduct Disorder ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Brain Regions ◽  
Posterior Cingulate Cortex ◽  
Chromosome 1 ◽  
Matter Volume ◽  
Cu Traits ◽  
Genetic And Environmental Factors

AbstractConduct disorder (CD), a psychiatric disorder characterized by a repetitive pattern of antisocial behaviors, results from a complex interplay between genetic and environmental factors. The clinical presentation of CD varies both according to the individual’s sex and level of callous-unemotional (CU) traits, but it remains unclear how genetic and environmental factors interact at the molecular level to produce these differences. Emerging evidence in males implicates methylation of genes associated with socio-affective processes. Here, we combined an epigenome-wide association study with structural neuroimaging in 51 females with CD and 59 typically developing (TD) females to examine DNA methylation in relation to CD, CU traits, and gray matter volume (GMV). We demonstrate an inverse pattern of correlation between CU traits and methylation of a chromosome 1 region in CD females (positive) as compared to TD females (negative). The identified region spans exon 1 of the SLC25A24 gene, central to energy metabolism due to its role in mitochondrial function. Increased SLC25A24 methylation was also related to lower GMV in multiple brain regions in the overall cohort. These included the superior frontal gyrus, prefrontal cortex, and supramarginal gyrus, secondary visual cortex and ventral posterior cingulate cortex, which are regions that have previously been implicated in CD and CU traits. While our findings are preliminary and need to be replicated in larger samples, they provide novel evidence that CU traits in females are associated with methylation levels in a fundamentally different way in CD and TD, which in turn may relate to observable variations in GMV across the brain.

scholarly journals Income is associated with hippocampal/amygdala and education with cingulate cortex grey matter volume

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
M. Lotze ◽  
M. Domin ◽  
C. O. Schmidt ◽  
N. Hosten ◽  
H. J. Grabe ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Anterior Cingulate Cortex ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Grey Matter Volume ◽  
Life Outcomes ◽  
Matter Volume ◽  
The Relationship

Abstract Income and education are both elements of a person’s socioeconomic status, which is predictive of a broad range of life outcomes. The brain’s gray matter volume (GMV) is influenced by socioeconomic status and mediators related to an unhealthy life style. We here investigated two independent general population samples comprising 2838 participants (all investigated with the same MRI-scanner) with regard to the association of indicators of the socioeconomic status and gray matter volume. Voxel-based morphometry without prior hypotheses revealed that years of education were positively associated with GMV in the anterior cingulate cortex and net-equivalent income with gray matter volume in the hippocampus/amygdala region. Analyses of possible mediators (alcohol, cigarettes, body mass index (BMI), stress) revealed that the relationship between income and GMV in the hippocampus/amygdala region was partly mediated by self-reported stressors, and the association of years of education with GMV in the anterior cingulate cortex by BMI. These results corrected for whole brain effects (and therefore not restricted to certain brain areas) do now offer possibilities for more detailed hypotheses-driven approaches.

Gray matter and intrinsic network changes in the posterior cingulate cortex after selective serotonin reuptake inhibitor intake

NeuroImage ◽  
2014 ◽  
Vol 84 ◽  
pp. 236-244 ◽  
Author(s):  
Christoph Kraus ◽  
Sebastian Ganger ◽  
Jan Losak ◽  
Andreas Hahn ◽  
Markus Savli ◽  
...  
Keyword(s):  
Selective Serotonin Reuptake Inhibitor ◽  
Reuptake Inhibitor ◽  
Gray Matter ◽  
Serotonin Reuptake ◽  
Cingulate Cortex ◽  
Posterior Cingulate Cortex ◽  
Selective Serotonin ◽  
Serotonin Reuptake Inhibitor ◽  
Posterior Cingulate

An epistasis effect of functional variants on the BDNF and DRD2 genes modulates gray matter volume of the anterior cingulate cortex in healthy humans

2010 ◽  
Vol 48 (4) ◽  
pp. 1016-1021 ◽  
Author(s):  
Christian Montag ◽  
Bernd Weber ◽  
Eva Jentgens ◽  
Christian Elger ◽  
Martin Reuter
Keyword(s):  
Anterior Cingulate Cortex ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Matter Volume ◽  
Healthy Humans ◽  
Functional Variants ◽  
Epistasis Effect

1H-MR spectroscopy and gray matter volume of the anterior cingulate cortex in schizophrenia

Neuroreport ◽  
2002 ◽  
Vol 13 (16) ◽  
pp. 2133-2137 ◽  
Author(s):  
H. Yamasue ◽  
T. Fukui ◽  
R. Fukuda ◽  
H. Yamada ◽  
S. Yamasaki ◽  
...  
Keyword(s):  
Anterior Cingulate Cortex ◽  
Gray Matter ◽  
Mr Spectroscopy ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Matter Volume ◽  
1H Mr Spectroscopy

Gray matter volume of rostral anterior cingulate cortex predicts rapid antidepressant response to ketamine

2020 ◽  
Author(s):  
Ana Herrera-Melendez ◽  
Anna Stippl ◽  
Sabine Aust ◽  
Milan Scheidegger ◽  
Erich Seifritz ◽  
...  
Keyword(s):  
Anterior Cingulate Cortex ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Antidepressant Response ◽  
Matter Volume ◽  
Rostral Anterior Cingulate Cortex

scholarly journals Anterior cingulate cortex gray matter volume mediates an association between 2D:4D ratio and trait aggression in women but not men

2015 ◽  
Vol 56 ◽  
pp. 148-156 ◽  
Author(s):  
Adam X. Gorka ◽  
Rachel E. Norman ◽  
Spenser R. Radtke ◽  
Justin M. Carré ◽  
Ahmad R. Hariri
Keyword(s):  
Anterior Cingulate Cortex ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Matter Volume ◽  
Trait Aggression

scholarly journals Increased Resting-State Interhemispheric Functional Connectivity of Posterior Superior Temporal Gyrus and Posterior Cingulate Cortex in Congenital Amusia

2021 ◽  
Vol 15 ◽  
Author(s):  
Zhishuai Jin ◽  
Sizhu Huyang ◽  
Lichen Jiang ◽  
Yajun Yan ◽  
Ming Xu ◽  
...  
Keyword(s):  
Functional Connectivity ◽  
Resting State ◽  
Music Perception ◽  
Superior Temporal Gyrus ◽  
Cingulate Cortex ◽  
Posterior Cingulate Cortex ◽  
Control Group ◽  
Neural Basis ◽  
Posterior Cingulate ◽  
Congenital Amusia

Interhemispheric connectivity of the two cerebral hemispheres is crucial for a broad repertoire of cognitive functions including music and language. Congenital amusia has been reported as a neurodevelopment disorder characterized by impaired music perception and production. However, little is known about the characteristics of the interhemispheric functional connectivity (FC) in amusia. In the present study, we used a newly developed voxel-mirrored homotopic connectivity (VMHC) method to investigate the interhemispheric FC of the whole brain in amusia at resting-state. Thirty amusics and 29 matched participants underwent a resting-state functional magnetic resonance imaging (fMRI) scanning. An automated VMHC approach was used to analyze the fMRI data. Compared to the control group, amusics showed increased VMHC within the posterior part of the default mode network (DMN) mainly in the posterior superior temporal gyrus (pSTG) and posterior cingulate cortex (PCC). Correlation analyses revealed negative correlations between the VMHC value in pSTG/PCC and the music perception ability among amusics. Further ROC analyses showed that the VMHC value of pSTG/PCC showed a good sensibility/specificity to differentiate the amusics from the controls. These findings provide a new perspective for understanding the neural basis of congenital amusia and imply the immature state of DMN may be a credible neural marker of amusia.

Differential effects of androgenic and anti-androgenic progestins on fusiform and frontal gray matter volume and face recognition performance

2015 ◽  
Vol 1596 ◽  
pp. 108-115 ◽  
Author(s):  
Belinda Pletzer ◽  
Martin Kronbichler ◽  
Hubert Kerschbaum
Keyword(s):  
Face Recognition ◽  
Gray Matter ◽  
Recognition Performance ◽  
Gray Matter Volume ◽  
Differential Effects ◽  
Matter Volume
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