scholarly journals Income is associated with hippocampal/amygdala and education with cingulate cortex grey matter volume

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
M. Lotze ◽  
M. Domin ◽  
C. O. Schmidt ◽  
N. Hosten ◽  
H. J. Grabe ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Anterior Cingulate Cortex ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Grey Matter Volume ◽  
Life Outcomes ◽  
Matter Volume ◽  
The Relationship

Abstract Income and education are both elements of a person’s socioeconomic status, which is predictive of a broad range of life outcomes. The brain’s gray matter volume (GMV) is influenced by socioeconomic status and mediators related to an unhealthy life style. We here investigated two independent general population samples comprising 2838 participants (all investigated with the same MRI-scanner) with regard to the association of indicators of the socioeconomic status and gray matter volume. Voxel-based morphometry without prior hypotheses revealed that years of education were positively associated with GMV in the anterior cingulate cortex and net-equivalent income with gray matter volume in the hippocampus/amygdala region. Analyses of possible mediators (alcohol, cigarettes, body mass index (BMI), stress) revealed that the relationship between income and GMV in the hippocampus/amygdala region was partly mediated by self-reported stressors, and the association of years of education with GMV in the anterior cingulate cortex by BMI. These results corrected for whole brain effects (and therefore not restricted to certain brain areas) do now offer possibilities for more detailed hypotheses-driven approaches.

1H-MR spectroscopy and gray matter volume of the anterior cingulate cortex in schizophrenia

Neuroreport ◽  
2002 ◽  
Vol 13 (16) ◽  
pp. 2133-2137 ◽  
Author(s):  
H. Yamasue ◽  
T. Fukui ◽  
R. Fukuda ◽  
H. Yamada ◽  
S. Yamasaki ◽  
...  
Keyword(s):  
Anterior Cingulate Cortex ◽  
Gray Matter ◽  
Mr Spectroscopy ◽  
Gray Matter Volume ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Matter Volume ◽  
1H Mr Spectroscopy

Serotonin - 1A binding in the subgenual anterior cingulate cortex is associated with regional grey matter volume in striatum and temporal areas

2011 ◽  
Vol 26 (S2) ◽  
pp. 934-934
Author(s):  
C. Kraus ◽  
M. Savli ◽  
A. Hahn ◽  
P. Baldinger ◽  
A. Höflich ◽  
...  
Keyword(s):  
Anterior Cingulate Cortex ◽  
Receptor Binding ◽  
Emotional Processing ◽  
Grey Matter ◽  
Ventral Striatum ◽  
Cingulate Cortex ◽  
Magnetic Resonance Images ◽  
Anterior Cingulate ◽  
Grey Matter Volume ◽  
Matter Volume

IntroductionThe subgenual part of the anterior cingulate cortex (sgACC) has been frequently reported to be structurally and cytoarchitectually changed in major depressive disorder (MDD) and is also a promising target in deep brain stimulation in treatment-resistant MDD. Furthermore, substantial evidence demonstrates a high density of serotonin-1A (5-HT1A) receptors in the sgACC, a key area involved in emotional processing.ObjectivesHere, we investigated the relationship between the 5-HT1A receptor in the sgACC and changes in regional grey matter volume with voxel-based morphometry.MethodsPET ([carbonyl-11C]WAY-100635) was used to quantify 5-HT1A receptor binding (BPND) together with structural magnetic resonance images from 32 healthy subjects (mean 26.68 ± 5.1 years; 17 women). Regression analysis was performed in SPM8 (p < .001 uncorr.) using sgACC 5-HT1A BPND as regressor, controlling for sex, age and total grey matter volume (GMV).Results5-HT1A BPND in the sgACC was positively associated with regional GMV in the medial temporal gyri (T=4.37) and nucleus accumbens bilaterally (T = 4.19). Furthermore, sgACC 5-HT1A binding was negatively correlated with GMV within the inferior temporal gyri (T = 5.22) and putamen bilaterally (T = 5.12).ConclusionsOur findings demonstrate structural relationships between sgACC 5-HT1A receptor binding and grey matter volume in the ventral striatum as well as in temporal regions, which both exhibit close neuronal connections with the sgACC. Moreover, the GMV of the ventral striatum has been reported to be decreased in patients with MDD. Conclusively, our results underpin the role of serotonergic neuronal transmission in cytoarchitectural processes within regions involved in the modulation of mood.

scholarly journals Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder

2009 ◽  
Vol 194 (5) ◽  
pp. 426-433 ◽  
Author(s):  
Alex Fornito ◽  
Murat Yücel ◽  
Stephen J. Wood ◽  
Andreas Bechdolf ◽  
Simon Carter ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Anterior Cingulate Cortex ◽  
Grey Matter ◽  
Cingulate Cortex ◽  
First Episode Psychosis ◽  
Anterior Cingulate ◽  
First Episode ◽  
Grey Matter Volume ◽  
Matter Volume ◽  
Episode Psychosis

BackgroundThe anterior cingulate cortex is frequently implicated in the pathophysiology of bipolar disorder, but magnetic resonance imaging (MRI) studies have reported variable findings owing to a reliance on patient samples with chronic illness and to limited appreciation of the region's heterogeneity.AimsTo characterise anterior cingulate cortex abnormalities in patients with bipolar disorder experiencing their first episode of psychosis while accounting for regional anatomical variability.MethodGrey matter volume, surface area and cortical thickness were measured in six anterior cingulate cortex subregions per hemisphere using MRI scans acquired from 26 patients with bipolar I disorder experiencing first-episode psychosis and 26 healthy controls matched for age, gender and regional morphological variability.ResultsRelative to controls, male patients displayed increased thickness in the right subcallosal limbic anterior cingulate cortex. No significant differences were identified in females for grey matter volume or surface area measures. The findings were not attributable to medication effects.ConclusionsThese data suggest that first-episode psychosis in bipolar disorder is associated with a gender-specific, right-lateralised thickness increase in anterior cingulate cortex subregions known to play a role in regulating physiological stress responses.

scholarly journals Anterior cingulate cortex grey matter volume abnormalities in adolescents with PTSD after childhood sexual abuse

2017 ◽  
Vol 27 (11) ◽  
pp. 1163-1171 ◽  
Author(s):  
Mirjam A. Rinne-Albers ◽  
J. Nienke Pannekoek ◽  
Marie-José van Hoof ◽  
Natasja D. van Lang ◽  
Francien Lamers-Winkelman ◽  
...  
Keyword(s):  
Sexual Abuse ◽  
Childhood Sexual Abuse ◽  
Anterior Cingulate Cortex ◽  
Grey Matter ◽  
Cingulate Cortex ◽  
Anterior Cingulate ◽  
Grey Matter Volume ◽  
Matter Volume
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