Entrainment by a palatable meal induces food-anticipatory activity and c-Fos expression in reward-related areas of the brain

Neuroscience ◽  
2005 ◽  
Vol 133 (1) ◽  
pp. 293-303 ◽  
Author(s):  
J. Mendoza ◽  
M. Angeles-Castellanos ◽  
C. Escobar
Keyword(s):  
Food Anticipatory Activity ◽  
Fos Expression ◽  
Anticipatory Activity ◽  
The Brain

Food entrainment modifies the c-Fos expression pattern in brain stem nuclei of rats

2005 ◽  
Vol 288 (3) ◽  
pp. R678-R684 ◽  
Author(s):  
Manuel Ángeles-Castellanos ◽  
Jorge Mendoza ◽  
Mauricio Díaz-Muñoz ◽  
Carolina Escobar
Keyword(s):  
Brain Stem ◽  
Neural Systems ◽  
Solitary Tract ◽  
Hypothalamic Nuclei ◽  
Food Anticipatory Activity ◽  
Neural Information ◽  
Meal Time ◽  
Differential Involvement ◽  
Anticipatory Activity ◽  
The Brain

When food is restricted to a few hours daily, animals increase their locomotor activity 2–3 h before food access, which has been termed food anticipatory activity. Food entrainment has been linked to the expression of a circadian food-entrained oscillator (FEO) and the anatomic substrate of this oscillator seems to depend on diverse neural systems and peripheral organs. Previously, we have described a differential involvement of hypothalamic nuclei in the food-entrained process. For the food entrainment pathway, the communication between the gastrointestinal system and central nervous system is essential. The visceral synaptic input to the brain stem arrives at the dorsal vagal complex and is transmitted directly from the nucleus of the solitary tract (NST) or via the parabrachial nucleus (PBN) to hypothalamic nuclei and other areas of the forebrain. The present study aims to characterize the response of brain stem structures in food entrainment. The expression of c-Fos immunoreactivity (c-Fos-IR) was used to identify neuronal activation. Present data show an increased c-Fos-IR following meal time in all brain stem nuclei studied. Food-entrained temporal patterns did not persist under fasting conditions, indicating a direct dependence on feeding-elicited signals for this activation. Because NST and PBN exhibited a different and increased response from that expected after a regular meal, we suggest that food entrainment promotes ingestive adaptations that lead to a modified activation in these brain stem nuclei, e.g., stomach distension. Neural information provided by these nuclei to the brain may provide the essential entraining signal for FEO.

Decreased food anticipatory activity of obese mice relates to hypothalamic c-Fos expression

2017 ◽  
Vol 179 ◽  
pp. 9-15 ◽  
Author(s):  
C. Luna-Illades ◽  
T. Morales ◽  
M. Miranda-Anaya
Keyword(s):  
Obese Mice ◽  
Food Anticipatory Activity ◽  
Fos Expression ◽  
Anticipatory Activity

FEEDING ENTRAINMENT OF FOOD-ANTICIPATORY ACTIVITY ANDper1EXPRESSION IN THE BRAIN AND LIVER OF ZEBRAFISH UNDER DIFFERENT LIGHTING AND FEEDING CONDITIONS

2010 ◽  
Vol 27 (7) ◽  
pp. 1380-1400 ◽  
Author(s):  
Jose F. López-Olmeda ◽  
Erica V. Tartaglione ◽  
Horacio O. de la Iglesia ◽  
Francisco J. Sánchez-Vázquez
Keyword(s):  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
The Brain

scholarly journals Food-entrained circadian rhythms are sustained in arrhythmic Clk/Clk mutant mice

2003 ◽  
Vol 285 (1) ◽  
pp. R57-R67 ◽  
Author(s):  
SiNae Pitts ◽  
Elizabeth Perone ◽  
Rae Silver
Keyword(s):  
Circadian Rhythms ◽  
Clock Gene ◽  
Wheel Running ◽  
Mutant Mice ◽  
Circadian Oscillators ◽  
Daily Food ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity ◽  
The Brain ◽  
Clock Protein

Daily scheduled feeding is a potent time cue that elicits anticipatory activity in rodents. This food-anticipatory activity (FAA) is controlled by a food-entrainable oscillator (FEO) that is distinct from light-entrained oscillators of the suprachiasmatic nucleus (SCN). Circadian rhythms within the SCN depend on transcription-translation feedback loops in which CLOCK protein is a key positive regulator. The Clock gene is expressed in rhythmic tissues throughout the brain and periphery, implicating its widespread involvement in the functioning of circadian oscillators. To examine whether CLOCK protein is also necessary for the FEO, the effect of daily food restriction was studied in homozygous Clock mutant ( Clk/Clk) mice. The results show that Clk/Clk mutant mice exhibit FAA, even when their circadian wheel-running behavior is arrhythmic. As in wild-type controls, FAA in Clk/Clk mutants persists after temporal feeding cues are removed for several cycles, indicating that the FEO is a circadian timer. This is the first demonstration that the Clock gene is not necessary for the expression of a circadian, food-entrained behavior and suggests that the FEO is mediated by a molecular mechanism distinct from that of the SCN.

C-fos Expression in the Brain Following Lithium Chloride Induced-Illness

2006 ◽  
Author(s):  
Katie M. Albanos ◽  
Steve Reilly ◽  
Justin R. St. Andre
Keyword(s):  
Lithium Chloride ◽  
Fos Expression ◽  
The Brain

Salicylate evokes c-fos expression in the brain stem

Neuroreport ◽  
1997 ◽  
Vol 8 (3) ◽  
pp. 725-728 ◽  
Author(s):  
E Wallhäusser-Franke
Keyword(s):  
Brain Stem ◽  
Fos Expression ◽  
The Brain

scholarly journals Sex differences in circadian food anticipatory activity are not altered by individual manipulations of sex hormones or sex chromosome copy number in mice

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0191373 ◽  
Author(s):  
Antonio Aguayo ◽  
Camille S. Martin ◽  
Timothy F. Huddy ◽  
Maya Ogawa-Okada ◽  
Jamie L. Adkins ◽  
...  
Keyword(s):  
Sex Differences ◽  
Sex Hormones ◽  
Copy Number ◽  
Sex Chromosome ◽  
Chromosome Copy Number ◽  
Food Anticipatory Activity ◽  
Anticipatory Activity
Sign in / Sign up

Export Citation Format

Share Document