Frontoparietal beta amplitude modulation and its interareal cross-frequency coupling in visual working memory

Neuroscience ◽  
2021 ◽  
Author(s):  
Wei-Kuang Liang ◽  
Philip Tseng ◽  
Jia-Rong Yeh ◽  
Norden E Huang ◽  
Chi-Hung Juan
Keyword(s):  
Working Memory ◽  
Visual Working Memory ◽  
Amplitude Modulation ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

scholarly journals Working Memory and Cross-Frequency Coupling of Neuronal Oscillations

2021 ◽  
Vol 12 ◽  
Author(s):  
Mohammed Abubaker ◽  
Wiam Al Qasem ◽  
Eugen Kvašňák
Keyword(s):  
Working Memory ◽  
Cognitive Impairment ◽  
Brain Stimulation ◽  
Large Body ◽  
Cognitive Outcomes ◽  
Essential Component ◽  
Non Invasive ◽  
Transcranial Alternating Current Stimulation ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

Working memory (WM) is the active retention and processing of information over a few seconds and is considered an essential component of cognitive function. The reduced WM capacity is a common feature in many diseases, such as schizophrenia, attention deficit hyperactivity disorder (ADHD), mild cognitive impairment (MCI), and Alzheimer's disease (AD). The theta-gamma neural code is an essential component of memory representations in the multi-item WM. A large body of studies have examined the association between cross-frequency coupling (CFC) across the cerebral cortices and WM performance; electrophysiological data together with the behavioral results showed the associations between CFC and WM performance. The oscillatory entrainment (sensory, non-invasive electrical/magnetic, and invasive electrical) remains the key method to investigate the causal relationship between CFC and WM. The frequency-tuned non-invasive brain stimulation is a promising way to improve WM performance in healthy and non-healthy patients with cognitive impairment. The WM performance is sensitive to the phase and rhythm of externally applied stimulations. CFC-transcranial-alternating current stimulation (CFC-tACS) is a recent approach in neuroscience that could alter cognitive outcomes. The studies that investigated (1) the association between CFC and WM and (2) the brain stimulation protocols that enhanced WM through modulating CFC by the means of the non-invasive brain stimulation techniques have been included in this review. In principle, this review can guide the researchers to identify the most prominent form of CFC associated with WM processing (e.g., theta/gamma phase-amplitude coupling), and to define the previously published studies that manipulate endogenous CFC externally to improve WM. This in turn will pave the path for future studies aimed at investigating the CFC-tACS effect on WM. The CFC-tACS protocols need to be thoroughly studied before they can be considered as therapeutic tools in patients with WM deficits.

scholarly journals Cross-frequency coupling supports multi-item working memory in the human hippocampus

2010 ◽  
Vol 107 (7) ◽  
pp. 3228-3233 ◽  
Author(s):  
N. Axmacher ◽  
M. M. Henseler ◽  
O. Jensen ◽  
I. Weinreich ◽  
C. E. Elger ◽  
...  
Keyword(s):  
Working Memory ◽  
Human Hippocampus ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

scholarly journals Neurocognitive subprocesses of working memory performance

2021 ◽  
Author(s):  
Agatha Lenartowicz ◽  
Holly Truong ◽  
Kristen D. Enriquez ◽  
Julia Webster ◽  
Jean-Baptiste Pochon ◽  
...  
Keyword(s):  
Working Memory ◽  
Memory Performance ◽  
Response Speed ◽  
Relevant Information ◽  
Care Seeking ◽  
Neural Responses ◽  
Stimulus Processing ◽  
Goal Maintenance ◽  
Frequency Coupling ◽  
Cross Frequency Coupling

AbstractWorking memory (WM) has been defined as the active maintenance and flexible updating of goal-relevant information in a form that has limited capacity and resists interference. Complex measures of WM recruit multiple subprocesses, making it difficult to isolate specific contributions of putatively independent subsystems. The present study was designed to determine whether neurophysiological indicators of proposed subprocesses of WM predict WM performance. We recruited 200 individuals defined by care-seeking status and measured neural responses using electroencephalography (EEG), while participants performed four WM tasks. We extracted spectral and time-domain EEG features from each task to quantify each of the hypothesized WM subprocesses: maintenance (storage of content), goal maintenance, and updating. We then used EEG measures of each subprocess as predictors of task performance to evaluate their contribution to WM. Significant predictors of WM capacity included contralateral delay activity and frontal theta, features typically associated with maintenance (storage of content) processes. In contrast, significant predictors of reaction time and its variability included contingent negative variation and the P3b, features typically associated with goal maintenance and updating. Broadly, these results suggest two principal dimensions that contribute to WM performance, tonic processes during maintenance contributing to capacity, and phasic processes during stimulus processing that contribute to response speed and variability. The analyses additionally highlight that reliability of features across tasks was greater (and comparable to that of WM performance) for features associated with stimulus processing (P3b and alpha), than with maintenance (gamma, theta and cross-frequency coupling).

scholarly journals Prefrontal Lesions Disrupt Posterior Alpha–Gamma Coordination of Visual Working Memory Representations

2021 ◽  
pp. 1-13
Author(s):  
Saeideh Davoudi ◽  
Mohsen Parto Dezfouli ◽  
Robert T. Knight ◽  
Mohammad Reza Daliri ◽  
Elizabeth L. Johnson
Keyword(s):  
Working Memory ◽  
Feature Selection ◽  
Visual Representations ◽  
Temporal Position ◽  
Memory Representations ◽  
Frequency Coupling ◽  
Oscillatory Mechanisms ◽  
Cross Frequency Coupling ◽  
Selection Of

Abstract How does the human brain prioritize different visual representations in working memory (WM)? Here, we define the oscillatory mechanisms supporting selection of “where” and “when” features from visual WM storage and investigate the role of pFC in feature selection. Fourteen individuals with lateral pFC damage and 20 healthy controls performed a visuospatial WM task while EEG was recorded. On each trial, two shapes were presented sequentially in a top/bottom spatial orientation. A retro-cue presented mid-delay prompted which of the two shapes had been in either the top/bottom spatial position or first/second temporal position. We found that cross-frequency coupling between parieto-occipital alpha (α; 8–12 Hz) oscillations and topographically distributed gamma (γ; 30–50 Hz) activity tracked selection of the distinct cued feature in controls. This signature of feature selection was disrupted in patients with pFC lesions, despite intact α–γ coupling independent of feature selection. These findings reveal a pFC-dependent parieto-occipital α–γ mechanism for the rapid selection of visual WM representations.

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