The relationship of oxidative metabolism to treatment response in major depression: A biological basis for treatment duration

2012 ◽  
Vol 18 (1) ◽  
pp. 15-18 ◽  
Author(s):  
Salih Selek ◽  
Alican Dalkilic ◽  
M. Cemal Kaya ◽  
Haluk A. Savas ◽  
Yasin Bez ◽  
...  
2012 ◽  
Vol 11 (3) ◽  
pp. 604-615 ◽  
Author(s):  
Medhi Wangpaichitr ◽  
Elizabeth J. Sullivan ◽  
George Theodoropoulos ◽  
Chunjing Wu ◽  
Min You ◽  
...  

1992 ◽  
Vol 180 (8) ◽  
pp. 491-497 ◽  
Author(s):  
MARY ELLEN McNAUGHTON ◽  
THOMAS L. PATTERSON ◽  
MICHAEL R. IRWIN ◽  
IGOR GRANT

Author(s):  
Kostas N. Fountoulakis ◽  
Apostolos Iacovides ◽  
George Gerasimou ◽  
Fotis Fotiou ◽  
Christina Ioannidou ◽  
...  

1988 ◽  
Vol 36 (9) ◽  
pp. 1161-1166 ◽  
Author(s):  
T Yamamoto ◽  
C V Gay

Histochemical detection of cytochrome oxidase activity in chicken growth plate revealed both positively and negatively stained mitochondria in chondrocytes of all zones, i.e., proliferative, pre-hypertrophic, hypertrophic, and calcifying zones. The proportion of positive to negative cells was lowest in the proliferative zone. As cytodifferentiation progressed, more positively stained cells were present. In positive cells all mitochondria were usually stained, and in negative cells all mitochondria were unstained. A few cells appeared to be in transition and contained both types of mitochondria. The results indicate that chondrocytes utilizing both aerobic and anaerobic metabolism are present in growth plate cartilage and that oxidative metabolism is favored in the more mature cells. The relationship of oxidative metabolism to calcification is discussed.


2001 ◽  
Vol 11 ◽  
pp. S236
Author(s):  
K.N. Fountoulakis ◽  
A. Iacovides ◽  
G. Gerasimou ◽  
F. Fotiou ◽  
Ch. Ioannidou ◽  
...  

2015 ◽  
Vol 76 (1) ◽  
pp. 3-14 ◽  
Author(s):  
Cun-Xian Jia ◽  
Jie Zhang

The aim of this research was to understand the characteristics of rural young suicides with major depression in China and the relationship of these events with Confucian values and negative life events. Our cases were 90 rural suicides with major depression with victims aged 15 to 34 years and living matched controls of the same gender, age (within 3 years), and county of residence. Confucian values appear to be a protective factor for men but a risk factor for women with regard to suicide with major depression. More attention should be paid to Confucian values in suicide prevention efforts.


2001 ◽  
Vol 158 (11) ◽  
pp. 1871-1877 ◽  
Author(s):  
Beth S. Brodsky ◽  
Maria Oquendo ◽  
Steven P. Ellis ◽  
Gretchen L. Haas ◽  
Kevin M. Malone ◽  
...  

2012 ◽  
Vol 43 (8) ◽  
pp. 1697-1702 ◽  
Author(s):  
N. Breslau ◽  
L. Schultz

BackgroundNeuroticism has been consistently correlated with the post-traumatic stress disorder (PTSD) response to traumatic events. Interpretation of these findings is limited by the retrospective nature of these findings: neuroticism was measured after the trauma had occurred. The prospective association of neuroticism with PTSD has not been examined (the relationship of neuroticism with PTSD symptoms was examined in a few prospective studies). We evaluate prospectively the relationship of neuroticism, measured at baseline, with the cumulative occurrence of PTSD during the subsequent 10 years, using data from a longitudinal epidemiological study of young adults.MethodA sample of 1007 young adults randomly selected from the membership of a large health maintenance organization in southeast Michigan was assessed at baseline and followed up at 3, 5 and 10 years later. We conducted a series of multinomial logistic regressions to estimate the relative risk (RR) of exposure to trauma and PTSD by neuroticism at baseline, adjusting for history of major depression (n = 990).ResultsDuring the 10-year follow-up, 50.2% of the sample experienced traumatic events and 5.2% developed PTSD. Neuroticism score at baseline increased significantly the RR of PTSD response to trauma. Additional analysis revealed that, among persons with history of major depression at baseline, RR for PTSD associated with neuroticism was equal to the null value of 1, but was increased significantly among those with no history of major depression.ConclusionsThe results confirm the role of neuroticism as diathesis in the PTSD response to traumatic experiences.


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