Neurotrophin-3 and neurotrophin-4: The unsung heroes that lies behind the meninges

Neuropeptides ◽  
2022 ◽  
pp. 102226
Author(s):  
Noor Azzizah Omar ◽  
Jaya Kumar ◽  
Teoh Seong Lin
Keyword(s):  
Neurotrophin 3

Neurotrophin 3 (NT3) stimulates colonic motility in awake rats

2001 ◽  
Vol 120 (5) ◽  
pp. A174-A175
Author(s):  
T ZITTEL ◽  
M KUEPERS ◽  
J GLATZLE ◽  
M KREIS ◽  
H BECKER ◽  
...  
Keyword(s):  
Colonic Motility ◽  
Neurotrophin 3 ◽  
Awake Rats

Biochemical Assessments of Neurotrophin-3 and Zinc Involvement in the Pathophysiology of Pediatric Febrile Seizures

2021 ◽  
Author(s):  
Ali Helmi Bakri ◽  
Mohammed H. Hassan ◽  
Ahmed El-Abd Ahmed ◽  
Pola Rafat Halim ◽  
Samer A. El-Sawy ◽  
...  
Keyword(s):  
Febrile Seizures ◽  
Neurotrophin 3

scholarly journals Cardio- and Neurometabolic Adipobiology: Consequences and Implications for Therapy

2021 ◽  
Vol 22 (8) ◽  
pp. 4137
Author(s):  
Jan Frohlich ◽  
George N. Chaldakov ◽  
Manlio Vinciguerra
Keyword(s):  
Skeletal Muscle ◽  
Adipose Tissue ◽  
Nerve Growth Factor ◽  
Human Life ◽  
Signaling Proteins ◽  
New Developments ◽  
Cardiometabolic Diseases ◽  
The Past ◽  
Neurotrophin 3

Studies over the past 30 years have revealed that adipose tissue is the major endocrine and paracrine organ of the human body. Arguably, adiopobiology has taken its reasonable place in studying obesity and related cardiometabolic diseases (CMDs), including Alzheimer’s disease (AD), which is viewed herein as a neurometabolic disorder. The pathogenesis and therapy of these diseases are multiplex at basic, clinical and translational levels. Our present goal is to describe new developments in cardiometabolic and neurometabolic adipobiology. Accordingly, we focus on adipose- and/or skeletal muscle-derived signaling proteins (adipsin, adiponectin, nerve growth factor, brain-derived neuroptrophic factor, neurotrophin-3, irisin, sirtuins, Klotho, neprilysin, follistatin-like protein-1, meteorin-like (metrnl), as well as growth differentiation factor 11) as examples of metabotrophic factors (MTFs) implicated in the pathogenesis and therapy of obesity and related CMDs. We argue that these pathologies are MTF-deficient diseases. In 1993 the “vascular hypothesis of AD” was published and in the present review we propose the “vasculometabolic hypothesis of AD.” We discuss how MTFs could bridge CMDs and neurodegenerative diseases, such as AD. Greater insights on how to manage the MTF network would provide benefits to the quality of human life.

scholarly journals Over-expression of neurotrophin 3 in human aortic valves affected by calcific disease induces the osteogenic responses via the Trk–Akt pathway

2015 ◽  
Vol 1852 (9) ◽  
pp. 1940-1949 ◽  
Author(s):  
Qingzhou Yao ◽  
Rui Song ◽  
Lihua Ao ◽  
Qiong Zhan ◽  
Joseph C. Cleveland ◽  
...  
Keyword(s):  
Akt Pathway ◽  
Aortic Valves ◽  
Over Expression ◽  
Neurotrophin 3

Poster #113 BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF), NEUROTROPHIN 3 (NTF3), NEUROTROPHIN 4 (NTF4) AND GLIAL-DERIVED NEUROTROPHIC FACTOR (GDNF) SERUM LEVELS IN SCHIZOPHRENIA

2012 ◽  
Vol 136 ◽  
pp. S132-S133
Author(s):  
Anna Leszczynska-Rodziewicz ◽  
Maria Skibinska ◽  
Pawel Kapelski ◽  
Aleksandra Rajewska-Rager ◽  
Joanna Pawlak ◽  
...  
Keyword(s):  
Neurotrophic Factor ◽  
Serum Levels ◽  
Brain Derived Neurotrophic Factor ◽  
Neurotrophin 3 ◽  
Glial Derived Neurotrophic Factor
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