Opioid use during pregnancy can impair maternal behavior and the Maternal Brain Network: A literature review

Objective: With the opioid epidemic reaching declared a public health emergency in recent years, a synthesis of recent knowledge outlining the impact of opioid use disorders on youth and families is needed. To this aim, this exploratory literature review examined how the role of family is discussed in research on youth opioid misuse, with the goal of acting as a springboard for further research and treatment development that could mitigate the negative impacts opioids are having on families and youth. Method: Peer-reviewed journal articles between 2008 and 2018 were accessed through PsycINFO in March 2018. A total of 279 unduplicated articles were identified through the search. Upon abstract and full-text review, a total of 21 articles met criteria for inclusion in the systematic review. Findings: Overall, the role of the family in adolescent opioid misuse was not commonly discussed in the literature, with 21 of 279 (7.5%) of articles meeting inclusion criteria for the current study. In the included articles, the following major themes were identified: (1) family factors affecting adolescent opioid misuse behavior and (2) family’s role in treatment of adolescent opioid misuse. Conclusions: The review evidences there is a relative paucity of literature on relational variables and youth opioid misuse. More practice-based scholarship, as well as more rigorous clinical research, is needed to inform future steps for clinical processes, policy, and research.

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Depression and Outcomes of Methadone and Buprenorphine Treatment Among People with Opioid Use Disorders: A Literature Review

Journal of Dual Diagnosis ◽

10.1080/15504263.2020.1726549 ◽

2020 ◽

Vol 16 (2) ◽

pp. 191-207

Author(s):

Maykel Farag Ghabrash ◽

Arash Bahremand ◽

Martine Veilleux ◽

Geneviève Blais-Normandin ◽

Gabrielle Chicoine ◽

...

Keyword(s):

Literature Review ◽

Opioid Use ◽

Opioid Use Disorders ◽

Buprenorphine Treatment

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Prolactin-Induced Mitogenesis in the Subventricular Zone of the Maternal Brain during Early Pregnancy Is Essential for Normal Postpartum Behavioral Responses in the Mother

Endocrinology ◽

10.1210/en.2009-1385 ◽

2010 ◽

Vol 151 (8) ◽

pp. 3805-3814 ◽

Cited By ~ 106

Author(s):

Caroline M. Larsen ◽

David R. Grattan

Keyword(s):

Early Pregnancy ◽

Maternal Behavior ◽

Subventricular Zone ◽

Prolactin Secretion ◽

Neural Progenitors ◽

Postpartum Anxiety ◽

Maternal Behaviors ◽

Maternal Brain ◽

Normal Expression ◽

Normal Increase

High prolactin during pregnancy, which is essential for normal postpartum maternal behavior, increases neurogenesis in the subventricular zone of the lateral ventricle (SVZ) of the maternal brain. Because SVZ mitogenesis generates new olfactory neurons and may contribute to perception of novel odorants, we hypothesized that the prolactin-induced increase in SVZ mitogenesis during pregnancy might be important for normal maternal interactions with pups. To investigate this hypothesis, prolactin secretion was suppressed for 3 d early in pregnancy in mice, using a carefully timed dose of bromocriptine. The bromocriptine-induced reduction in prolactin prevented the normal increase in generation of neural progenitors in the SVZ of the maternal brain. Another group of bromocriptine-treated animals were allowed to continue their pregnancy until term, and then maternal behaviors were evaluated postpartum. Low prolactin during early pregnancy, and the consequent suppression of mitogenesis in the SVZ of the maternal brain, was subsequently followed by increased postpartum anxiety and markedly impaired maternal behavior. In another group of pregnant females, injections of the mitotic inhibitor methylazoxymethanol to specifically suppress neurogenesis in the mother during early pregnancy without affecting prolactin secretion also caused postpartum anxiety and impaired maternal behavior. These data demonstrate that prolactin-induced increase in generation of neural progenitors in the SVZ of the maternal brain during early pregnancy is required for normal expression of postpartum maternal behaviors.

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Mother Brain is Wired for Social Moments

10.1101/2020.05.31.125955 ◽

2020 ◽

Author(s):

Ortal Shimon-Raz ◽

Roy Salomon ◽

Miki Bloch ◽

Gabi Aisenberg Romano ◽

Talma Hendler ◽

...

Keyword(s):

Neural Response ◽

Brain Network ◽

Behavior Patterns ◽

Placebo Administration ◽

Social Brain ◽

Double Blind ◽

Generational Transmission ◽

The Social ◽

Maternal Brain ◽

Brain Behavior

AbstractReorganization of the maternal brain, primed by oxytocin surge during childbirth, triggers the species-typical maternal social behavior. These brief social moments carry profound effects on the infant’s social brain and likely have a distinct signature in the maternal brain. Utilizing a double-blind, oxytocin/placebo administration crossover design, we imaged mothers twice while observing three naturalistic maternal-infant contexts in the home ecology; “unavailable”, “unresponsive”, and “social”, when mothers engaged in synchronous pick-a-boo play. We found four processes by which mother’s brain registers social moments. Salience - social moments increased activations throughout the maternal brain network; Brain-behavior coupling - caregiving behavior linked with socially-driven neural response; Oxytocin sensitivity – administration impacted neural response mainly to the social context; and Temporal engrams–consistent temporal patterns in insula and TP characterized response to social play. Findings describe how mother’s brain compiles and amplifies these precious social moments to generate dyad-specific brain-behavior patterns that initiate the cross-generational transmission of human sociality.

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A Narrative Literature Review of the Epidemiology, Etiology, and Treatment of Co-Occurring Panic Disorder and Opioid Use Disorder

Journal of Dual Diagnosis ◽

10.1080/15504263.2021.1965407 ◽

2021 ◽

pp. 1-20

Author(s):

Ashton E. Clark ◽

Shelby R. Goodwin ◽

Russell M. Marks ◽

Annabelle M. Belcher ◽

Emily Heinlein ◽

...

Keyword(s):

Panic Disorder ◽

Literature Review ◽

Opioid Use Disorder ◽

Opioid Use ◽

Narrative Literature ◽

Narrative Literature Review

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Exposure to glyphosate and glyphosate-based herbicides during the perinatal period affect maternal behavior and maternal brain plasticity

Toxicology Letters ◽

10.1016/j.toxlet.2017.07.423 ◽

2017 ◽

Vol 280 ◽

pp. S151 ◽

Cited By ~ 1

Author(s):

Julie Dechartres ◽

Jodi L. Pawluski ◽

Niece Nmezu ◽

Charlène Renoult ◽

Thierry D. Charlier

Keyword(s):

Maternal Behavior ◽

Brain Plasticity ◽

Perinatal Period ◽

Maternal Brain

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A Narrative Systematic Literature Review: A Focus on Qualitative Studies on HIV and Medication-Assisted Therapy in the United States

Pharmacy ◽

10.3390/pharmacy9010067 ◽

2021 ◽

Vol 9 (1) ◽

pp. 67

Author(s):

Alina Cernasev ◽

Sunitha Kodidela ◽

Michael P. Veve ◽

Theodore Cory ◽

Hilary Jasmin ◽

...

Keyword(s):

United States ◽

Literature Review ◽

Healthcare Providers ◽

The United States ◽

Hiv And Aids ◽

Opioid Use ◽

Screening Process ◽

Persons Living With Hiv ◽

Opioid Medications

Over the last two decades, the United States (U.S.) has experienced an opioid crisis that has had a significant negative societal and economic impact. Due to the high utilization of opioids in Persons Living with HIV and AIDS (PLWHA), there is a need for a qualitative literature review that presents opioid-use related problems in this population. This study aims to present and identify a thematic overview of the qualitative manuscripts on PLWHA who take opioid medications in the U.S., with a focus on perceptions surrounding medication assisted therapy. The systematic literature search was performed in December 2019. Four databases were searched: PubMed/MEDLINE, Scopus, Web of Science, and Cumulative Index to Nursing & Allied Health Literature (CINAHL). A total of 5348 results were exported from databases into EndNote x9, and duplicates were removed for a total of 3039 unique abstracts to screen. The records were imported into Rayyan, an online platform designed to expedite the screening process. Three authors screened titles and abstracts and determined 19 articles that would be screened in full text. On 9 April 2020, it was determined that eight articles would be included for review. The analysis of the eight manuscripts that fit the inclusion and exclusion criteria revealed barriers and facilitators to medication assisted therapy (MAT) in PLWHA. This review communicates or describes the story of PLWHA who might have delayed access to HIV healthcare providers and the commencement of antiretroviral therapy. In the literature, several studies have focused on the role of physicians in prescribing and addressing the medication regimens but none of the studies examined the role of pharmacists in access to care in this population. Therefore, further research is needed for a better understanding of the social aspects of taking opioid medications in PLWHA and the role of pharmacists within the continuum of care.

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The use of auricular acupuncture in opioid use disorder: A systematic literature review

American Journal on Addictions ◽

10.1111/ajad.12453 ◽

2016 ◽

Vol 25 (8) ◽

pp. 592-602 ◽

Cited By ~ 12

Author(s):

Tanya E. Baker ◽

Grace Chang

Keyword(s):

Literature Review ◽

Systematic Literature Review ◽

Opioid Use Disorder ◽

Auricular Acupuncture ◽

Opioid Use

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Does Integrative Medicine Reduce Prescribed Opioid Use/Dose for Chronic Pain? A Systematic Literature Review

Advances in Integrative Medicine ◽

10.1016/j.aimed.2019.03.291 ◽

2019 ◽

Vol 6 ◽

pp. S100

Author(s):

Samah Hassan ◽

QingPing Zheng ◽

Erica Rizzolo ◽

Evrim Tezcanli ◽

Sukriti Bhardwaj ◽

...

Keyword(s):

Chronic Pain ◽

Literature Review ◽

Integrative Medicine ◽

Systematic Literature Review ◽

Opioid Use

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Factors influencing nurses’ knowledge and attitudes toward patients in chronic pain with opioid use disorder: A literature review

Journal of Nursing Education and Practice ◽

10.5430/jnep.v10n9p37 ◽

2020 ◽

Vol 10 (9) ◽

pp. 37

Author(s):

Suha Abdulwahab ◽

Vahe Kehyayan ◽

Atef Al-Tawafsheh

Keyword(s):

Chronic Pain ◽

Literature Review ◽

Health Care Professionals ◽

Opioid Use Disorder ◽

Common Symptom ◽

Inclusion Criteria ◽

Opioid Use ◽

Knowledge And Attitudes ◽

Factors Influencing ◽

Nurses Knowledge

Background and objective: Chronic pain is a common symptom among patients worldwide. This issue leads health care professionals to manage patients’ chronic pain by using opioids. However, some patients tend to abuse these medications and develop opioid use disorder. The aim of the study was to identify and explore factors that influence nurses’ knowledge and attitudes toward patients in chronic pain with opioid use disorder.Methods: A literature review was conducted. CINAHL, Medline, and PsychINFO databases were used to search for relevant articles. A total of 12 articles that met the inclusion criteria were retrieved.Results: This literature review showed several factors that influence nurses’ knowledge and attitudes. These factors were nurses’ education, role support, demographic factors, nurses’ experiences, and nurses’ beliefs and culture.Conclusions: The findings of this literature review will inform the development of an educational program to promote nurses’ knowledge and attitudes toward patients in chronic pain with opioid use disorder.

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