Association of Healthy Eating Index and oxidative stress in adolescent volleyball athletes and non-athletes

Abstract Background: Although many studies suggest an association between BDNF Val66Met with eating disorders and obesity especially in type 2 diabetes mellitus (T2DM), the interaction between BDNF Val66Met polymorphism and diet quality indices in diabetic patients have not been investigated yet. The current study was aimed to evaluate the interaction between the diet quality indices including Healthy Eating Index (HEI), Diet Quality Index-International (DQI-I), Phytochemical Index (PI) and BDNF Val66Mat (rs6265) polymorphism on markers of inflammation, and oxidative stress in T2DM patients.Methods: This current cross-sectional study was conducted on 634 Iranian T2DM patients aged 35–65 years of both genders were randomly recruited. Dietary intakes was estimated by a food frequency questionnaire (FFQ) with 148 food items. All participants were categorized into three categories, based on DQI, HEI, and PI scores. The interactions were tested using analysis of covariance (ANCOVA) in adjusted and unadjusted models.Results: There were significant gene-diet interactions between BDNF Val66Met polymorphism and HEI, DQI, and PI scores in modulating body mass index (BMI) and waist circumference (WC) values. Our results showed that higher scores for all diet-quality indices were significantly associated with a lower BMI and WC values after adjustment (P Interactions < 0.05). We also observed a significant interaction between the DQI scores and Val66Met polymorphism on level of superoxide dismutase (SOD) (p-interaction= 0.01). The highest quartile of DQI was associated with elevated level of SOD in the Val/Met and Met/Met genotype group. Moreover, the interaction between the DQI scores and Val66Met polymorphism on total antioxidant capacity (TAC) tended to be significant.Conclusions: Higher scores for all diet-quality indices were significantly associated with a lower BMI and WC values. There were significant differences for PTX and PGF2A among HEI tertiles. The interaction between the polymorphism and DQI on TAC and SOD levels were significant.

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The interaction between brain-derived neurotrophic factor (BDNF) Val66met polymorphism and dietary indices, The Healthy Eating Index (HEI), The Diet Quality Index-International (DQI-I), and Phytochemical index (PI), on anthropometric indices, inflammatory, and oxidative stress markers in patient with type2 diabetes

10.21203/rs.3.rs-239163/v1 ◽

2021 ◽

Author(s):

Fariba Koohdani ◽

Zeinab Naeini ◽

Negin Aghazadeh ◽

Elmira Karimi ◽

Zahra Esmaeily ◽

...

Keyword(s):

Oxidative Stress ◽

Healthy Eating ◽

Diet Quality ◽

Quality Index ◽

Healthy Eating Index ◽

Quality Indices ◽

Val66met Polymorphism ◽

Diet Quality Index ◽

Bdnf Val66met Polymorphism ◽

And Oxidative Stress

Abstract Background: Although many studies suggest an association between BDNF Val66Met with eating disorders and obesity especially in type 2 diabetes mellitus (T2DM), the interaction between BDNF Val66Met polymorphism and diet quality indices in diabetic patients have not been investigated yet. The current study was aimed to evaluate the interaction between the diet quality indices including Healthy Eating Index (HEI), Diet Quality Index-International (DQI-I), Phytochemical Index (PI) and BDNF Val66Mat (rs6265) polymorphism on markers of inflammation, and oxidative stress in T2DM patients.Methods: This current cross-sectional study was conducted on 634 Iranian T2DM patients aged 35–65 years of both genders were randomly recruited. Dietary intakes was estimated by a food frequency questionnaire (FFQ) with 148 food items. All participants were categorized into three categories, based on DQI, HEI, and PI scores. The interactions were tested using analysis of covariance (ANCOVA) in adjusted and unadjusted models.Results: There were significant gene-diet interactions between BDNF Val66Met polymorphism and HEI, DQI, and PI scores in modulating body mass index (BMI) and waist circumference (WC) values. Our results showed that higher scores for all diet-quality indices were significantly associated with a lower BMI and WC values after adjustment (P Interactions < 0.05). We also observed a significant interaction between the DQI scores and Val66Met polymorphism on level of superoxide dismutase (SOD) (p-interaction= 0.01). The highest quartile of DQI was associated with elevated level of SOD in the Val/Met and Met/Met genotype group. Moreover, the interaction between the DQI scores and Val66Met polymorphism on total antioxidant capacity (TAC) tended to be significant.Conclusions: Higher scores for all diet-quality indices were significantly associated with a lower BMI and WC values. There were significant differences for PTX and PGF2A among HEI tertiles. The interaction between the polymorphism and DQI on TAC and SOD levels were significant.

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Diet Quality Is Associated with Serum Antioxidant Capacity in Women with Breast Cancer: A Cross Sectional Study

Nutrients ◽

10.3390/nu13010115 ◽

2020 ◽

Vol 13 (1) ◽

pp. 115

Author(s):

Luiza K. Reitz ◽

Sheyla de L. Baptista ◽

Elaine da S. Santos ◽

Patrícia F. Hinnig ◽

Gabriele Rockenbach ◽

...

Keyword(s):

Breast Cancer ◽

Oxidative Stress ◽

Adjuvant Treatment ◽

Diet Quality ◽

Cell Injury ◽

Healthy Eating Index ◽

Oxidative Stress Biomarkers ◽

Oxidative Stress Parameters ◽

And Oxidative Stress ◽

Stress Parameters

Oxidative stress produced by adjuvant treatments is associated with cell injury; however, a healthy diet can help mitigate it. The aim of this study is to investigate the association between diet quality and oxidative stress parameters in women subjected to adjuvant treatment for breast cancer. The sample comprised 70 women. Oxidative stress biomarkers and diet quality parameters based on the Brazilian Healthy Eating Index—Revised (BHEI-R)—were evaluated at baseline (p0) and after adjuvant treatment (p1). Ferric reducing antioxidant potential (FRAP) was associated with diet quality at p0. BHEI-R scores were not different between p0 and p1; however, scores from total vegetables, total fruits, milk and dairy products, and meat, eggs and legumes were lower during treatment. On the other hand, lower sodium and saturated fat intake observed at p1 counterbalanced the BHEI-R score. Oxidative stress parameters have increased at p1, but they were not associated with diet quality; thus, changes in component intake were not enough to promote changes in oxidative stress during treatment. It appears that diet can enhance patients’ antioxidant defense before treatment, which could lead to better outcomes in the long term. Further investigations may help to clarify the association between diet and oxidative stress in women with breast cancer.

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Comparison of Different Dietary Indices as Predictors of Inflammation, Oxidative Stress and Intestinal Microbiota in Middle-Aged and Elderly Subjects

Nutrients ◽

10.3390/nu12123828 ◽

2020 ◽

Vol 12 (12) ◽

pp. 3828

Author(s):

Sergio Ruiz-Saavedra ◽

Nuria Salazar ◽

Ana Suárez ◽

Clara G. de los Reyes-Gavilán ◽

Miguel Gueimonde ◽

...

Keyword(s):

Oxidative Stress ◽

Mediterranean Diet ◽

Intestinal Microbiota ◽

Healthy Eating ◽

Healthy Eating Index ◽

Dietary Inflammatory Index ◽

Mediterranean Diet Score ◽

Inflammatory Index ◽

Diet Score ◽

Dietary Indices

During the last decades the gut microbiota has been identified as a key mediator in the diet-health interaction. However, our understanding on the impact of general diet upon microbiota is still limited. Dietary indices represent an essential approach for addressing the link between diet and health from a holistic point of view. Our aim was to test the predictive potential of seven dietary ratings on biomarkers of inflammation, oxidative stress and on the composition and metabolic activity of the intestinal microbiota. A cross-sectional descriptive study was conducted on a sample of 73 subjects aged >50 years with non-declared pathologies. Dietary inflammatory index (DII), Empirical Dietary Inflammatory Index (EDII), Healthy Eating Index (HEI), Alternative Healthy Eating Index (AHEI), Mediterranean adapted Diet Quality Index-International (DQI-I), Modified Mediterranean Diet Score (MMDS) and relative Mediterranean Diet Score (rMED) were calculated based on a Food Frequency Questionnaire. Major phylogenetic types of the intestinal microbiota were determined by real time polymerase chain reaction (qPCR) and fecal short chain fatty acids (SCFAs) by gas chromatography. While DII, HEI, DQI-I and MMDS were identified as predictors of Faecalibacterium prausnitzii levels, AHEI and MMDS were negatively associated with Lactobacillus group. HEI, AHEI and MMDS were positively associated with fecal SCFAs. In addition, DII and EDII explained lipoperoxidation level and Mediterranean scores the serum IL-8 concentrations. The lower detection of IL-8 in individuals with higher scores on Mediterranean indices may be partially explained by the increased levels of the anti-inflammatory bacterium F. prausnitzii in such individuals.

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1638: Erectile Dysfunction and Oxidative Stress-Media Ted Cavernosal Cell Death in Spontaneously Hypertensive Rats

The Journal of Urology ◽

10.1016/s0022-5347(18)38846-3 ◽

2004 ◽

Vol 171 (4S) ◽

pp. 433-433

Author(s):

Steven Kuntz ◽

Steven White ◽

Michael Alba ◽

Mahadevan Rajasekaran

Keyword(s):

Oxidative Stress ◽

Cell Death ◽

Erectile Dysfunction ◽

Spontaneously Hypertensive Rats ◽

Hypertensive Rats ◽

Spontaneously Hypertensive ◽

And Oxidative Stress

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Association between calcitriol and paricalcitol with oxidative stress in patients with hemodialysis

International Journal for Vitamin and Nutrition Research ◽

10.1024/0300-9831/a000641 ◽

2020 ◽

pp. 1-8

Author(s):

Hasan Haci Yeter ◽

Berfu Korucu ◽

Elif Burcu Bali ◽

Ulver Derici

Keyword(s):

Oxidative Stress ◽

Vitamin D ◽

Antioxidant Status ◽

Total Antioxidant Status ◽

Stress Index ◽

Total Oxidant Status ◽

Vitamin D Analog ◽

Total Antioxidant ◽

Oxidant Status ◽

And Oxidative Stress

Abstract. Background: The pathophysiological basis of chronic kidney disease and its complications, including cardiovascular disease, are associated with chronic inflammation and oxidative stress. We investigated the effects of active vitamin D (calcitriol) and synthetic vitamin D analog (paricalcitol) on oxidative stress in hemodialysis patients. Methods: This cross-sectional study was composed of 83 patients with a minimum hemodialysis vintage of one year. Patients with a history of any infection, malignancy, and chronic inflammatory disease were excluded. Oxidative markers (total oxidant and antioxidant status) and inflammation markers (C-reactive protein and interleukin-6) were analyzed. Results: A total of 47% (39/83) patients were using active or analog vitamin D. Total antioxidant status was significantly higher in patients with using active or analog vitamin D than those who did not use (p = 0.006). Whereas, total oxidant status and oxidative stress index were significantly higher in patients with not using vitamin D when compared with the patients who were using vitamin D preparation (p = 0.005 and p = 0.004, respectively). On the other hand, total antioxidant status, total oxidant status, and oxidative stress index were similar between patients who used active vitamin D or vitamin D analog (p = 0.6; p = 0.4 and p = 0.7, respectively). Conclusion: The use of active or selective vitamin D analog in these patients decreases total oxidant status and increases total antioxidant status. Also, paricalcitol is as effective as calcitriol in decreasing total oxidant status and increasing total antioxidant status in patients with chronic kidney disease.

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