Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients

2012 ◽  
Vol 32 (6) ◽  
pp. 421-427 ◽  
Author(s):  
Pawel Bogdanski ◽  
Joanna Suliburska ◽  
Monika Szulinska ◽  
Marta Stepien ◽  
Danuta Pupek-Musialik ◽  
...  
2009 ◽  
Vol 28 (4) ◽  
pp. 355-361 ◽  
Author(s):  
Isabelle Hininger-Favier ◽  
Rachida Benaraba ◽  
Sara Coves ◽  
Richard A. Anderson ◽  
Anne-Marie Roussel

2012 ◽  
Vol 2012 ◽  
pp. 1-11 ◽  
Author(s):  
Kuo-Jen Wu ◽  
Ming-Tsuen Hsieh ◽  
Chi-Rei Wu ◽  
W. Gibson Wood ◽  
Yuh-Fung Chen

Ischemic stroke results in brain damage and behavioral deficits including memory impairment. Protective effects of green tea extract (GTex) and its major functional polyphenol (−)-epigallocatechin gallate (EGCG) on memory were examined in cerebral ischemic rats. GTex and EGCG were administered 1 hr before middle cerebral artery ligation in rats. GTex, EGCG, and pentoxifylline (PTX) significantly improved ishemic-induced memory impairment in a Morris water maze test. Malondialdehyde (MDA) levels, glutathione (GSH), and superoxide dismutase (SOD) activity in the cerebral cortex and hippocampus were increased by long-term treatment with GTex and EGCG. Both compounds were also associated with reduced cerebral infraction breakdown of MDA and GSH in the hippocampus. Inin vitroexperiments, EGCG had anti-inflammatory effects in BV-2 microglia cells. EGCG inhibited lipopolysaccharide- (LPS-) induced nitric oxide production and reduced cyclooxygenase-2 and inducible nitric oxide synthase expression in BV-2 cells. GTex and its active polyphenol EGCG improved learning and memory deficits in a cerebral ischemia animal model and such protection may be due to the reduction of oxidative stress and neuroinflammation.


2012 ◽  
Vol 224 (2) ◽  
pp. 377-383 ◽  
Author(s):  
Sang-Hyun Ihm ◽  
Sung-Won Jang ◽  
Ok-Ran Kim ◽  
Kiyuk Chang ◽  
Min-Ho Oak ◽  
...  

2018 ◽  
Vol 57 ◽  
pp. 170-179 ◽  
Author(s):  
Rosemari Otton ◽  
Anaysa Paola Bolin ◽  
Leticia Torres Ferreira ◽  
Marcelo Paradiso Marinovic ◽  
Andrea Livia Silva Rocha ◽  
...  

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