Characterization of laser droplet formation by reflected light

2006 ◽  
Vol 44 (5) ◽  
pp. 398-410 ◽  
Author(s):  
Jure Klemenčič ◽  
Tadej Kokalj ◽  
Peter Mužič ◽  
Igor Grabec ◽  
Edvard Govekar
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kiyoto Kamagata ◽  
Rika Chiba ◽  
Ichiro Kawahata ◽  
Nanako Iwaki ◽  
Saori Kanbayashi ◽  
...  

AbstractLiquid droplets of aggregation-prone proteins, which become hydrogels or form amyloid fibrils, are a potential target for drug discovery. In this study, we proposed an experiment-guided protocol for characterizing the design grammar of peptides that can regulate droplet formation and aggregation. The protocol essentially involves investigation of 19 amino acid additives and polymerization of the identified amino acids. As a proof of concept, we applied this protocol to fused in sarcoma (FUS). First, we evaluated 19 amino acid additives for an FUS solution and identified Arg and Tyr as suppressors of droplet formation. Molecular dynamics simulations suggested that the Arg additive interacts with specific residues of FUS, thereby inhibiting the cation–π and electrostatic interactions between the FUS molecules. Second, we observed that Arg polymers promote FUS droplet formation, unlike Arg monomers, by bridging the FUS molecules. Third, we found that the Arg additive suppressed solid aggregate formation of FUS, while Arg polymer enhanced it. Finally, we observed that amyloid-forming peptides induced the conversion of FUS droplets to solid aggregates of FUS. The developed protocol could be used for the primary design of peptides controlling liquid droplets and aggregates of proteins.


Author(s):  
Masaharu Hyodo ◽  
Osamu Matoba ◽  
Satoru Miyauchi ◽  
Shingo Saito
Keyword(s):  

1987 ◽  
Vol 62 (10) ◽  
pp. 4248-4254 ◽  
Author(s):  
L. D. Partain ◽  
S. M. Dean ◽  
B. L. Berard ◽  
P. S. McLeod ◽  
L. M. Fraas ◽  
...  

1998 ◽  
Vol 44 (147) ◽  
pp. 326-332 ◽  
Author(s):  
Laurent Arnaud ◽  
Michel Gay ◽  
Jean-Marc Barnola ◽  
Paul Duval

AbstractA new technique for characterizing the structure of firn and bubbly ice is presented. This technique, based on observation of etched (sublimation) surfaces in coaxial reflected light, enables une to see simultaneously the pore network of the firn or bubbles in the ice and the crystal boundaries. At the same time, the main stages of image processing used to transform the initial photographs into clean binary images are described.


2019 ◽  
Vol 131 (9-10) ◽  
pp. 1581-1590 ◽  
Author(s):  
L.M. Alva-Valdivia ◽  
A. Agarwal ◽  
B. García-Amador ◽  
W. Morales-Barrera ◽  
K.K. Agarwal ◽  
...  

Abstract The Xalapa monogenetic volcanic field, Veracruz, Mexico is located at the eastern end of the Trans-Mexican Volcanic Belt. This study uses specimens from 0.8 ka to 5.96 ± 0.156 Ma Xalapa lava deposits and from 4.5 ± 0.028 Ma La Concha ignimbrite. The study identifies the magnetic mineralogy by reflected light microscopy, thermomagnetic curves, and coercivity estimates. It further defines the magnetic domain size distribution by hysteresis plots, Day diagrams, and first-order-reversal-curves. Characteristic remanent directions and virtual geomagnetic poles are also calculated. The characteristic remanent directions are used to establish the magnetostratigraphy and to identify the net rotation experienced, at each site, since the emplacement. The results allow the identification of the rotation domains, and R′-, P-, and Y-shears, active since the past ∼2.5 m.y. in the region and a better characterization of the displacement along the Río Actopan fault, active in the Xalapa monogenetic volcanic field.


2011 ◽  
Vol 314-316 ◽  
pp. 2334-2337
Author(s):  
Jae Hyun Yoo ◽  
Young Woo Park ◽  
Kyung Hyun Yoon ◽  
Eun Ju Yoo

This paper presents the experimental characterization of droplet formation in accordance with different types of driving waveform. The objective of the experiments is to generate sound droplets with a minimal volume depending on the types of driving waveform. For it, two types of driving waveform are used to investigate the droplet formation of the M-Jet: one is bipolar and another W-shaped. In the case of the bipolar waveform, ti lead to fluid flows from the liquid reservoir into the chamber in the M-Jet and th is time to impose a pulse under the constant magnetic field, resulting in the formation of the droplets. The droplet volume decreases as ti increases, and increases with further increase of ti. The threshold ti is equal to 500 s. The droplet volume decreases as th decreases, but the droplet formation was not successful at less than 550 s. In the case of the W-shaped waveform, maintains ti and th where is set from bipolar waveform, control the tr, where retracted MM keeps to control droplet volume. The tail becomes longer as tr increases. The droplet volume remains nearly constant as tr increases, but rapidly increases with further increase of tr. When the two driving waveform, the W-shaped driving waveform seems to be effective in reducing the droplet volume, and achieves the reduction of volume by 30 percent.


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