S102 – Mometasone Furoate Reduces Severity of Adenoidal Hypertrophy

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P111-P112
Author(s):  
Talal Nsouli
Keyword(s):  
Treatment Group ◽  
Skin Prick Test ◽  
Upper Airway ◽  
Mometasone Furoate ◽  
Control Group ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Prick Test ◽  
History Of ◽  
Adenoidal Hypertrophy

Objectives Allergic rhinitis (AR) is a risk factor for adenoidal hypertrophy—the adenoids are the lymphoid tissue closest to the nasal mucosa—and results in upper airway obstruction and snoring. The efficacy of mometasone furoate nasal spray (MFNS) in reducing gland size and degree of snoring in subjects with adenoidal hypertrophy and concomitant AR was assessed. Methods Children 5 to 10 years old with adenoidal hypertrophy and a history of chronic nasal obstruction and snoring received MFNS 50 mcg QD in each nostril. 16 subjects with AR diagnosed by positive skin prick test to environmental allergens comprised the treatment group, and 8 subjects with no history of AR and a negative skin prick test comprised the control group. Efficacy variables, assessed at Weeks 0 (baseline), 4, and 8, were change in size of the adenoid gland, evaluated by flexible fiber-optic and graded as a percentage according to degree of obliteration of the choanae, and change in degree of snoring, evaluated on a 3-point scale (0 absent, 1 intermittent, or 2 continuous). Results Significant improvements in the treatment group vs. baseline at Week 8 were an 84% decrease in mean average adenoidal-tissue size, compared with a 5% decrease in the control group (P less than 0.05) and an 80% decrease in snoring compared with a 5% decrease in the control group (P less than 0.05). Conclusions Once-daily MFNS 50 mcg is beneficial in the treatment of adenoidal hypertrophy and in reducing snoring in pediatric patients with AR.

scholarly journals Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children

2013 ◽  
Vol 131 (5) ◽  
pp. 301-308 ◽  
Author(s):  
Raquel Prudente de Carvalho Baldacara ◽  
Maria de Fatima Marcelos Fernandes ◽  
Leonardo Baldacara ◽  
Wilson Tartuce Aun ◽  
Joao Ferreira de Mello ◽  
...  
Keyword(s):  
Family History ◽  
Skin Prick Test ◽  
Cesarean Delivery ◽  
Atopic Disease ◽  
Dermatophagoides Pteronyssinus ◽  
Outpatient Clinics ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Prick Test ◽  
History Of

CONTEXT AND OBJECTIVE: Knowledge of the profile of allergen sensitization among children is important for planning preventive measures. The objective of this study was to assess the prevalence and profile of sensitization to inhaled allergens and food among children and adolescents in an outpatient population in the city of Palmas. DESIGN AND SETTING: Cross-sectional study at outpatient clinics in Palmas, Tocantins, Brazil. METHODS: Ninety-four patients aged 1-15 years who were attending two pediatric outpatient clinics were selected between September and November 2008. All of the subjects underwent clinical interviews and skin prick tests. RESULTS: A positive skin prick test was observed in 76.6% of the participants (72.3% for inhalants and 28.9% for food allergens). The most frequent allergens were Dermatophagoides pteronyssinus (34%), cat epithelium (28.7%), dog epithelium (21.3%), Dermatophagoides farinae (19.1%), Blomia tropicalis (18.1%), cow's milk (9.6%) and grasses (9.6%). A positive skin prick test correlated with a history of atopic disease (odds ratio, OR = 5.833; P = 0.002), a family history of atopic disease (OR = 8.400; P < 0.001), maternal asthma (OR = 8.077; P = 0.048), pet exposure (OR = 3.600; P = 0.012) and cesarean delivery (OR = 3.367; P = 0.019). CONCLUSION: Dermatophagoides pteronyssinus was the most frequent aeroallergen and cow’s milk was the most prevalent food allergen. There was a positive correlation between a positive skin prick test and several factors, such as a family history of atopic disease, maternal asthma, pet exposure and cesarean delivery.

scholarly journals Prevalence and associated factors of airway hyper- responsiveness in children with recurrent chronic cough

2016 ◽  
Vol 44 (5) ◽  
pp. 181 ◽  
Author(s):  
I Gusti Agung Ngurah Sugitha Adnyana ◽  
Putu Suwendra ◽  
Hendra Santoso
Keyword(s):  
Skin Prick Test ◽  
Passive Smoking ◽  
Chronic Cough ◽  
Associated Factors ◽  
Positive Skin Prick Test ◽  
Cross Sectional ◽  
Positive Skin ◽  
Cough Variant Asthma ◽  
Prick Test ◽  
History Of

Background Airway hyper-responsiveness (AH) is a common char-acteristic of asthma. Patient who has recurrent chronic cough withAH is commonly referred as “cough variant asthma”. Histamineprovocation test should be performed to determine whether a pa-tient has “cough variant asthma” or recurrent viral bronchitis.Objective To determine AH prevalence in children with recurrentchronic cough and factors associated with it.Methods A cross sectional study was conducted on 6-12 year-oldchildren with recurrent chronic cough at the Pediatrics OutpatientClinic, Sanglah Hospital Denpasar from September 2002 until June2003Results Twenty one out of 64 (33%) subjects suffering from recur-rent chronic cough without wheezing had AH. Associated factorssignificantly associated with AH were age, allergic rhinitis, pater-nal and maternal history of atopy, passive smoking, use of mos-quito-coil, positive skin prick test, and eosinophilia. Spearman cor-relation analysis between associated factors and AH showed thatpositive skin prick test and passive smoking were moderately cor-related with AH (r=0.56, p<0.0001; r=0.57, p<0.0001, respectively),whereas multivariate regression logistic analysis on associatedfactors found true associated factors, such as positive skin pricktest (p=0.01; OR=14.82), history of atopy in father (p=0.02;OR=22.75), and passive smoking (p=0.03; OR=11.97).Conclusions The prevalence of airway hyper-responsiveness inchildren with recurrent chronic cough without history of wheezingwas 33%. Independent associated factors of AH in recurrent chroniccough children are positive skin prick test, history of atopy in fa-ther, and passive smoking

Impact of Allergic Rhinitis on Voice in Children

ORL ◽  
2021 ◽  
pp. 1-6
Author(s):  
Serap Sahin Onder ◽  
Fatih Savran ◽  
Burak Karabulut ◽  
Mehmet Surmeli ◽  
Aysen Cetemen
Keyword(s):  
Allergic Rhinitis ◽  
Skin Prick Test ◽  
Fundamental Frequency ◽  
Diagnostic Process ◽  
Control Group ◽  
Positive Skin Prick Test ◽  
Voice Change ◽  
Positive Skin ◽  
Prick Test ◽  
Maximum Phonation Time

Introduction: The purpose of the present study was to determine the possible effect of allergic rhinitis (AR) on voice change in children with acoustic analysis and Turkish children’s voice handicap index-10 (TR-CVHI-10). Methods: This is a case-control study. Forty-one children with AR, and a positive skin prick test, as well as 39 children of controls who had produced a negative skin prick test and lacked a history of allergic disease, were selected for the study. Each assessment included recordings for the purposes of acoustic voice analysis (fundamental frequency [f0], jitter %, shimmer %, and harmonics-to-noise ratio (HNR)), and aerodynamic analysis (maximum phonation time (MPT) and s/z ratio). All participants completed TR-CVHI-10. Results: The mean TR-CVHI-10 score of the AR group was significantly higher than the control group (p = 0.013). No difference was observed between the AR and control groups in terms of jitter, shimmer, HNR, and MPT values and s/z ratio (p > 0.05). Conversely, the f0 value was more pronounced in controls (270.9 ± 60.3 Hz) than in the AR group (237.7 ± 54.3 Hz) (p = 0.012). Conclusion: The study’s results revealed that AR can have an effect on fundamental frequency and voice quality in children. The diagnostic process should include AR as a potential cause of voice disorders in children.

scholarly journals Is Atopy Related to Neuroticism, Stress, and Subjective Quality of Life?

2009 ◽  
Vol 60 (1) ◽  
pp. 99-107 ◽  
Author(s):  
Biserka Radošević-Vidaček ◽  
Adrijana Košćec ◽  
Marija Bakotić ◽  
Jelena Macan ◽  
Jasminka Bobić
Keyword(s):  
Quality Of Life ◽  
Skin Prick Test ◽  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Positive Skin Prick Test ◽  
Subjective Quality Of Life ◽  
Positive Skin ◽  
Prick Test

Is Atopy Related to Neuroticism, Stress, and Subjective Quality of Life?Different psychosocial characteristics have been associated with allergic disorders. The aim of this study was to examine whether atopic constitution and reports of allergic symptoms were related to personality trait of neuroticism, exposure to stressful life events and estimates of quality of life. Atopy was determined by skin prick test and reports of nasal and pulmonary allergy-related symptoms. Actively working individuals of both genders took part in the study (n=145, age range: 20 to 66 years). The participants were divided in three groups. The first group was composed of those with negative skin prick test and without symptoms (n=57), the second of those with positive skin prick test but without symptoms (n=28), and the third of those with positive skin prick test and symptoms (n=60). The groups did not differ significantly in neuroticism, exposure to stressful life events, or quality of life. Women reported more pronounced neuroticism and anxiety, higher exposure to stressful life events, and were less satisfied with their environment than men. In our sample of active workers we found no association of neuroticism, exposure to stressful life events, and quality of life with atopy and allergic symptoms.

Identification of patatin as a novel allergen for children with positive skin prick test responses to raw potato

1999 ◽  
Vol 103 (1) ◽  
pp. 165-171 ◽  
Author(s):  
Ulla Seppälä ◽  
Harri Alenius ◽  
Kristiina Turjanmaa ◽  
Timo Reunala ◽  
Timo Palosuo ◽  
...  
Keyword(s):  
Skin Prick Test ◽  
Positive Skin Prick Test ◽  
Positive Skin ◽  
Prick Test

scholarly journals Food allergies in children: a comparison of parental reports and skin prick test results

2018 ◽  
Vol 58 (2) ◽  
pp. 59-65
Author(s):  
Camilia Metadea Aji Savitri ◽  
Azwin Mengindra Putera Lubis ◽  
Gatot Soegiarto
Keyword(s):  
Skin Prick Test ◽  
Skin Prick Testing ◽  
Food Allergies ◽  
P Value ◽  
Positive Skin Prick Test ◽  
Test Results ◽  
Cross Sectional ◽  
Positive Skin ◽  
Prick Test ◽  
Parental Reports

Background Food allergy is common in children and its prevalence is generally on the rise. Imprecise parental reports about reactions to particular foods can lead to unnecessary restrictions. Since children have specific growth requirements, such nutritional restrictions may have disturbing effects on children’s growth and development.Objective To compare parental reports on food reactions to skin prick test results in their children.Method Retrospective, cross sectional study using patient’s medical record data during one-year study period. Data were analyzed manually and statistically, to assess the degree of agreement (Kappa’s coefficient) and significance (P).Results We collected data from 154 subjects aged 0-18 years. For every allergen assessed, parents reported more food reactions than positive skin prick test results. Allergy incidence were caused, in order, by cow’s milk and chicken (25.3%), eggs (22.1%), chocolate (20.1%), fruits (14.3%), seafood (13%), and saltwater fish (1.9%). Kappa coefficient are all poor (<0.2) and P value are all >0.05 except for chicken (P=0.02).Conclusion Most parents tend to overestimate which food cause reactions in their children, as reactions reported were not necessarily allergenic. Therefore, every patient experiencing allergy reactions should undergo skin prick testing to confirm the possibility of allergy.

Atopy and Quality of Life in Pediatric Chronic Rhinosinusitis

2019 ◽  
Vol 33 (5) ◽  
pp. 586-590 ◽  
Author(s):  
Anamika Anamika ◽  
Arunabha Chakravarti ◽  
Raj Kumar
Keyword(s):  
Quality Of Life ◽  
Skin Prick Test ◽  
Chronic Rhinosinusitis ◽  
Cross Sectional Study ◽  
Endoscopic Examination ◽  
Positive Skin Prick Test ◽  
Cross Sectional ◽  
Positive Skin ◽  
Prick Test

Background Atopy has been suggested in the development of chronic rhinosinusitis (CRS), as allergic rhinitis (AR) is common coexisting disease in pediatric and adult patients with CRS. The contribution of AR to CRS is less clear till date. Objectives The objectives of this study were to determine atopic profile of children with CRS and impact of atopic status on disease severity and quality of life. Methods One hundred ten patients, aged between 7 and 18 years of age, diagnosed with CRS based on history, detailed clinical examination including nasal endoscopic examination were included in this cross-sectional study. Scoring of CRS was done according to Lund Mackay Endoscopic Appearance Score. Patients underwent skin prick test against 65 common aeroallergens (1:10 w/v, 50% glycerinated) for evidence of atopy. SN-5 Sinus and Nasal Quality of Life Survey was used to assess the quality of life in the study subjects. Results Positive skin prick test to at least one of the common aeroallergens was present in 58 (52.7%) patients. Most common aeroallergen sensitivity was seen with insects in 48 (43.6%) patients. Patients of CRS with atopy had higher mean Lund Mackay endoscopic score and SN-5 score than nonatopic patients which was statistically significant. Conclusion In conclusion, we recommend that testing for aeroallergen sensitivity and assessment of quality of life should be included in the protocol for diagnosis and management of pediatric patients with CRS. Early diagnosis and treatment of allergy may halt the progression of CRS and also the development of asthma and other allergic multimorbid disorders.

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