Fish age, instead of weight and size, as a determining factor for time course differences in cortisol response to stress

2012 ◽  
Vol 107 (3) ◽  
pp. 397-400 ◽  
Author(s):  
Leonardo José Gil Barcellos ◽  
Luiz Carlos Kreutz ◽  
Gessi Koakoski ◽  
Thiago Acosta Oliveira ◽  
João Gabriel Santos da Rosa ◽  
...  
Keyword(s):  
Time Course ◽  
Cortisol Response ◽  
Response To Stress ◽  
Determining Factor

Divergent time course of cortisol response to stress in fish of different ages

2012 ◽  
Vol 106 (2) ◽  
pp. 129-132 ◽  
Author(s):  
Gessi Koakoski ◽  
Thiago Acosta Oliveira ◽  
João Gabriel Santos da Rosa ◽  
Michele Fagundes ◽  
Luiz Carlos Kreutz ◽  
...  
Keyword(s):  
Time Course ◽  
Cortisol Response ◽  
Different Ages ◽  
Response To Stress

scholarly journals Influence of sex and gonadal status of sheep on cortisol secretion in response to ACTH and on cortisol and LH secretion in response to stress: importance of different stressors

2002 ◽  
Vol 173 (1) ◽  
pp. 113-122 ◽  
Author(s):  
AI Turner ◽  
BJ Canny ◽  
RJ Hobbs ◽  
JD Bond ◽  
IJ Clarke ◽  
...  
Keyword(s):  
Sex Differences ◽  
Sex Difference ◽  
Restraint Stress ◽  
Cortisol Response ◽  
Blood Samples ◽  
Response To Stress ◽  
Lh Secretion ◽  
Gonadal Status ◽  
Major Mediator

There are sex differences in the response to stress and in the influence of stress on reproduction which may be due to gonadal steroids but the nature of these differences and the role of the gonads are not understood. We tested the hypotheses that sex and the presence/absence of gonads (gonadal status) will influence the cortisol response to injection of ACTH, insulin-induced hypoglycaemia and isolation/restraint stress, and that sex and gonadal status will influence the secretion of LH in response to isolation/restraint stress. Four groups of sheep were used in each of three experiments: gonad-intact rams, gonadectomised rams, gonad-intact ewes in the mid-luteal phase of the oestrous cycle and gonadectomised ewes. In Experiment 1 (n=4/group), jugular blood samples were collected every 10 min for 6 h; after 3 h, two animals in each group were injected (i.v.) with ACTH and the remaining two animals were injected (i.v.) with saline. Treatments were reversed 5 days later so that every animal received both treatments. Experiment 2 (n=4/group) used a similar schedule except that insulin was injected (i.v.) instead of ACTH. In Experiment 3 (n=5/group), blood samples were collected every 10 min for 16 h on a control day and again 2 weeks later when, after 8 h of sampling, all sheep were isolated and restrained for 8 h. Plasma cortisol was significantly (P<0.05) elevated following injection of ACTH or insulin and during isolation/restraint stress. There were no significant differences between the sexes in the cortisol response to ACTH. Rams had a greater (P<0.05) cortisol response to insulin-induced hypoglycaemia than ewes while ewes had a greater (P<0.05) cortisol response to isolation/restraint stress than rams. There was no effect of gonadal status on these parameters. Plasma LH was suppressed (P<0.05) in gonadectomised animals during isolation/restraint stress but was not affected in gonad-intact animals, and there were no differences between the sexes. Our results show that the sex that has the greater cortisol response to a stressor depends on the stressor imposed and that these sex differences are likely to be at the level of the hypothalamo-pituitary unit rather than at the adrenal gland. Since there was a sex difference in the cortisol response to isolation/restraint, the lack of a sex difference in the response of LH to this stress suggests that glucocorticoids are unlikely to be a major mediator of the stress-induced suppression of LH secretion.

scholarly journals Sex Differences in the Ovine Fetal Cortisol Response to Stress

2011 ◽  
Vol 69 (2) ◽  
pp. 118-122 ◽  
Author(s):  
Dino A Giussani ◽  
Andrew J W Fletcher ◽  
David S Gardner
Keyword(s):  
Sex Differences ◽  
Cortisol Response ◽  
Response To Stress ◽  
Ovine Fetal

scholarly journals Gallop Racing Shifts Mature mRNA towards Introns: Does Exercise-Induced Stress Enhance Genome Plasticity?

Genes ◽  
2020 ◽  
Vol 11 (4) ◽  
pp. 410
Author(s):  
Katia Cappelli ◽  
Samanta Mecocci ◽  
Silvia Gioiosa ◽  
Andrea Giontella ◽  
Maurizio Silvestrelli ◽  
...  
Keyword(s):  
Time Course ◽  
Mononuclear Cells ◽  
Peripheral Blood Mononuclear ◽  
Coding Regions ◽  
Transcription Modulation ◽  
Response To Stress ◽  
Differential Gene ◽  
Exercise Induced ◽  
Regulatory Functions ◽  
Genomic Repeats

Physical exercise is universally recognized as stressful. Among the “sport species”, the horse is probably the most appropriate model for investigating the genomic response to stress due to the homogeneity of its genetic background. The aim of this work is to dissect the whole transcription modulation in Peripheral Blood Mononuclear Cells (PBMCs) after exercise with a time course framework focusing on unexplored regions related to introns and intergenic portions. PBMCs NGS from five 3 year old Sardinian Anglo-Arab racehorses collected at rest and after a 2000 m race was performed. Apart from differential gene expression ascertainment between the two time points the complexity of transcription for alternative transcripts was identified. Interestingly, we noted a transcription shift from the coding to the non-coding regions. We further investigated the possible causes of this phenomenon focusing on genomic repeats, using a differential expression approach and finding a strong general up-regulation of repetitive elements such as LINE. Since their modulation is also associated with the “exonization”, the recruitment of repeats that act with regulatory functions, suggesting that there might be an active regulation of this transcriptional shift. Thanks to an innovative bioinformatic approach, our study could represent a model for the transcriptomic investigation of stress.

scholarly journals Adiposity and Cortisol Response to Stress in Indian Adolescents

2017 ◽  
Vol 55 (2) ◽  
pp. 125-130
Author(s):  
G. V. Krishnaveni ◽  
A. Jones ◽  
S. R. Veena ◽  
R. Somashekara ◽  
S. C. Karat ◽  
...  
Keyword(s):  
Cortisol Response ◽  
Indian Adolescents ◽  
Response To Stress

PARADOXICAL RESPONSE OF PLASMA CORTISOL TO PULSE INTRAVENOUS INJECTION OF SYNTHETIC CORTICOTROPHIN AND DIBUTYRYL CYCLIC ADENOSINE 3′,5′-MONOPHOSPHATE IN ADULT PANHYPOPITUITARISM

1973 ◽  
Vol 74 (2) ◽  
pp. 250-262 ◽  
Author(s):  
Alberto Angeli ◽  
Roberto Frajria ◽  
Giuseppe Boccuzzi ◽  
Daniela Bisbocci ◽  
Franco Ceresa
Keyword(s):  
Plasma Cortisol ◽  
Time Course ◽  
Normal Subjects ◽  
Specific Cell ◽  
Acute Administration ◽  
Cortisol Response ◽  
Experimental Conditions ◽  
Paradoxical Response ◽  
Early Peak ◽  
Membrane Bound

ABSTRACT 250 μg of synthetic β-1-24 corticotrophin and 10 mg/kg of dibutyryl cyclic adenosine 3′,5′-monophosphate (Db-cAMP) were iv pulse injected into six patients with adult panhypopituitarism. The plasma cortisol levels were determined as 11-OHCS at zero time and then at 2.5, 5, 7.5, 10, 15, 30, 60 and 180 min after the injection. The data were compared with those obtained under the same experimental conditions in groups of normal subjects. A paradoxical pattern of early plasma cortisol response after the two stimuli was found in the case of hypopituitarism in comparison with that observed in normal subjects, that is a higher response after Db-cAMP than after corticotrophin. This was dependent on a selective impairment of adrenal steroidogenic response to iv injection of corticotrophin, whereas the response to iv injection of Db-cAMP was normal. Moreover in hypopituitaric patients the time course of cortisol response after ACTH was clearly different from the normal. The plasma 11-OHCS levels never showed an early peak followed by a fall and a second subsequent rise but rose progressively after the injection to a plateau between 15 and 180 min. By contrast, after Db-cAMP the time course of the response was also similar to that observed in normal subjects. It is suggested that after chronic failure of ACTH the reduced cortisol response to iv acute administration of corticotrophin may also depend on a defect localized before the synthesis of intracellular cyclic AMP, i. e. in the binding between ACTH and the specific cell membrane bound receptor and/or in the inactivation of the membrane associated adenyl cyclase.

scholarly journals Long-term effects of maternal deprivation on the corticosterone response to stress in rats

1997 ◽  
Vol 273 (4) ◽  
pp. R1332-R1338 ◽  
Author(s):  
Deborah Suchecki ◽  
Sergio Tufik
Keyword(s):  
Time Course ◽  
Maternal Deprivation ◽  
Group Differences ◽  
Saline Injection ◽  
Long Term Effects ◽  
Male And Female ◽  
Response To Stress ◽  
Corticosterone Response ◽  
Adrenal Response

Twenty-four hours of maternal deprivation result in activation of the infant rat’s adrenocortical axis. In the present study we examined the long-term effects of maternal deprivation on the corticosterone (Cort) response to stress. Pups were maternally deprived (Dep) on postnatal day( PND) 11 and tested immediately ( PND 12) or returned to their mothers and tested at later ages. Testing consisted of a time course of the Cort response to a saline injection (5, 15, 30, and 60 min). At PND 12, the response of Dep pups was higher than that of nondeprived (non-Dep) pups. No group differences were observed at PND 16 and 22. On PND 30, Dep rats showed lower Cort levels than non-Dep pups at 0, 5, and 30 min after saline. At PND 60, non-Dep females showed higher Cort levels than males at 5, 15, and 30 min. This gender difference for Dep pups was observed only at 5 min. Male and female Dep animals presented lower Cort levels than non-Dep counterparts at 60 and 30 min after saline, respectively. These findings indicate that maternal deprivation effects on Cort secretion are long lasting. Dep rats showed a smaller adrenal response to stress at PND 30, whereas as adults the stress response was similar but the turnoff was different.

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